TRANSLOCATION

MOLECULAR BASIS OF ANTIBIOTIC TRANSLOCATION

 Coordinatore JACOBS UNIVERSITY BREMEN GGMBH 

 Organization address address: Campus Ring 1
city: BREMEN
postcode: 28759

contact info
Titolo: Mr.
Nome: Ronald
Cognome: Kieschnick
Email: send email
Telefono: +49 421 2004515

 Nazionalità Coordinatore Germany [DE]
 Totale costo 3˙304˙341 €
 EC contributo 3˙304˙341 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-2013-ITN
 Funding Scheme MC-ITN
 Anno di inizio 2013
 Periodo (anno-mese-giorno) 2013-09-01   -   2017-08-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    JACOBS UNIVERSITY BREMEN GGMBH

 Organization address address: Campus Ring 1
city: BREMEN
postcode: 28759

contact info
Titolo: Mr.
Nome: Ronald
Cognome: Kieschnick
Email: send email
Telefono: +49 421 2004515

DE (BREMEN) coordinator 625˙640.18
2    UNIVERSITA DEGLI STUDI DI CAGLIARI

 Organization address address: VIA UNIVERSITA 40
city: CAGLIARI
postcode: 9124

contact info
Titolo: Prof.
Nome: Luciano
Cognome: Colombo
Email: send email
Telefono: 390707000000
Fax: 39070510171

IT (CAGLIARI) participant 663˙400.72
3    THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS

 Organization address address: NORTH STREET 66 COLLEGE GATE
city: ST ANDREWS FIFE
postcode: KY16 9AJ

contact info
Titolo: Ms.
Nome: Trish
Cognome: Starrs
Email: send email
Telefono: +44 0 1334467286
Fax: +44 0 1334462217

UK (ST ANDREWS FIFE) participant 285˙056.64
4    UNIVERSITY OF NEWCASTLE UPON TYNE

 Organization address address: Kensington Terrace 6
city: NEWCASTLE UPON TYNE
postcode: NE1 7RU

contact info
Titolo: Dr.
Nome: Amanda
Cognome: Gregory
Email: send email
Telefono: +44 191 282 4514
Fax: +44 191 282 4524

UK (NEWCASTLE UPON TYNE) participant 285˙056.64
5    BioVersys AG

 Organization address address: Hochbergerstrasse 60c
city: Basel
postcode: 4057

contact info
Titolo: Dr.
Nome: Marc
Cognome: Gitzinger
Email: send email
Telefono: +41 61 6332250
Fax: +41 61 6332259

CH (Basel) participant 261˙515.76
6    UNIVERSITAET BASEL

 Organization address address: Petersplatz 1
city: BASEL
postcode: 4003

contact info
Titolo: Prof.
Nome: Dirk
Cognome: Bumann
Email: send email
Telefono: +41 61 267 23 82
Fax: +41 61 267 21 18

CH (BASEL) participant 261˙515.76
7    UNIVERSITE D'AIX MARSEILLE

 Organization address address: Boulevard Charles Livon 58
city: Marseille
postcode: 13284

contact info
Titolo: Ms.
Nome: Celine
Cognome: Damon
Email: send email
Telefono: 33491998595
Fax: 33491998599

FR (Marseille) participant 255˙948.66
8    FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V

 Organization address address: Hansastrasse 27C
city: MUENCHEN
postcode: 80686

contact info
Titolo: Mr.
Nome: Michael
Cognome: Prestele
Email: send email
Telefono: +49 8912052738

DE (MUENCHEN) participant 222˙068.88
9    JOHANN WOLFGANG GOETHE UNIVERSITAET FRANKFURT AM MAIN

 Organization address address: GRUNEBURGPLATZ 1
city: FRANKFURT AM MAIN
postcode: 60323

contact info
Titolo: Prof.
Nome: Martin
Cognome: Pos
Email: send email
Telefono: +069 798 29251
Fax: +069 798 29201

DE (FRANKFURT AM MAIN) participant 222˙068.88
10    Nanion Technologies GmbH

 Organization address address: GABRIELENSTRASSE 9
city: MUNCHEN
postcode: 80636

contact info
Titolo: Dr.
Nome: Niels
Cognome: Fertig
Email: send email
Telefono: +089 2189 97972
Fax: +089 2189 97960

DE (MUNCHEN) participant 222˙068.88
11    EUROPEAN SCREENINGPORT GMBH

 Organization address address: SCHNACKENBURGALLEE 114
city: HAMBURG
postcode: 22525

contact info
Titolo: Dr.
Nome: Philip
Cognome: Gribbon
Email: send email
Telefono: +49 403037640
Fax: 4940300000000

DE (HAMBURG) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

screening    pharmaceutical    influx    antibiotic    antibiotics    antibacterial    resistant    drug    bacteria    faculty    moreover    efflux    companies    boarder    cellular   

 Obiettivo del progetto (Objective)

'Multidrug resistant bacteria are now ubiquitous in both hospitals and the larger community. Drug-resistant pathogens are becoming increasingly pervasive, for example, the resurrection of tuberculosis provides one ominous example highlighting the risk associated with evolved drug resistance. Moreover, many pharmaceutical companies abandoned this field and no truly novel active antibacterial compounds are currently in clinical trials. Obviously we need new antibacterial molecules and maybe, novel strategies to develop antibiotics. The novel aspect here is to use state-in-the art techniques to quantify rate limiting steps of individual components involved antibiotic penetration and to validate them at the cellular level. Such a system biology approach identifies bottlenecks of existing antibiotics and might suggest novel antibiotic therapy. In Gram-negative bacteria, where influx and efflux systems located in the Outer Membrane represent a physical bottleneck for any antibiotic to reach a potential target. The aim is to investigate the molecular and cellular mechanisms at the basis of the influx and efflux processes and to teach scientists with different scientific background to go beyond the classical faculty boarder. Bringing nanotechnology, physics, chemistry, computer modeling, pharmacology, microbiology together will facilitate the transfer of expertise acquired within the network in both academic and industry. To achieve these goals we propose a training program allowing young researcher to collaborate across traditional faculty boarder. Three partners from the private sector will actively participate, the first one is a SME developing unique nanodevices allowing high-throughput drug screening in the field of electrophysiology, the second one is engaged in developing novel antibiotics and the third one is working on drug screening and characterization. Moreover three global pharmaceutical companies will accept students for secondments.'

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HTSCS IN PLACENTA (2014)

Origin and lineage specification of trophoblast cells in early human placenta

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AMBER (2013)

Advanced Multidisciplinary Training in Molecular Bacteriology

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MIMYCS (2010)

"MIMYCS, A framework for simulating maize kernels mycotoxin contamination in Europe"

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