INDOX

Optimized oxidoreductases for medium and large scale industrial biotransformations

 Coordinatore AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS 

 Organization address address: CALLE SERRANO 117
city: MADRID
postcode: 28006

contact info
Titolo: Ms.
Nome: María ángeles
Cognome: López Vázquez
Email: send email
Telefono: +34 915681462
Fax: +34 915681573

 Nazionalità Coordinatore Spain [ES]
 Totale costo 11˙196˙317 €
 EC contributo 7˙825˙824 €
 Programma FP7-KBBE
Specific Programme "Cooperation": Food, Agriculture and Biotechnology
 Code Call FP7-KBBE-2013-7-single-stage
 Funding Scheme CP-TP
 Anno di inizio 2013
 Periodo (anno-mese-giorno) 2013-11-01   -   2016-10-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS

 Organization address address: CALLE SERRANO 117
city: MADRID
postcode: 28006

contact info
Titolo: Ms.
Nome: María ángeles
Cognome: López Vázquez
Email: send email
Telefono: +34 915681462
Fax: +34 915681573

ES (MADRID) coordinator 2˙048˙325.00
2    TECHNISCHE UNIVERSITEIT DELFT

 Organization address address: Stevinweg 1
city: DELFT
postcode: 2628 CN

contact info
Titolo: Dr.
Nome: Frank
Cognome: Hollmann
Email: send email
Telefono: +31 152781957

NL (DELFT) participant 592˙075.00
3    WAGENINGEN UNIVERSITY

 Organization address address: DROEVENDAALSESTEEG 4
city: WAGENINGEN
postcode: 6708 PB

contact info
Titolo: Mr.
Nome: Tom
Cognome: Bessems
Email: send email
Telefono: +31 317484478

NL (WAGENINGEN) participant 575˙993.00
4    TECHNISCHE UNIVERSITAET DRESDEN

 Organization address address: HELMHOLTZSTRASSE 10
city: DRESDEN
postcode: 1069

contact info
Titolo: Mr.
Nome: Sven
Cognome: Kreigenfeld
Email: send email
Telefono: 4935150000000

DE (DRESDEN) participant 572˙700.00
5    NOVOZYMES A/S

 Organization address address: Krogshoejvej 36
city: BAGSVAERD
postcode: 2880

contact info
Titolo: Dr.
Nome: Henrik
Cognome: Lund
Email: send email
Telefono: +45 44468502

DK (BAGSVAERD) participant 516˙921.00
6    INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE

 Organization address address: Rue De L'Universite 147
city: PARIS CEDEX 07
postcode: 75338

contact info
Titolo: Mrs.
Nome: Sylvie
Cognome: Modeste
Email: send email
Telefono: +33 4 32722067
Fax: +33 4 32722072

FR (PARIS CEDEX 07) participant 496˙677.00
7    UNIVERSITAET FUER BODENKULTUR WIEN

 Organization address address: Gregor Mendel Strasse 33
city: WIEN
postcode: 1180

contact info
Titolo: Dr.
Nome: Roland
Cognome: Ludwig
Email: send email
Telefono: +431 476546149
Fax: +43 1476546199

AT (WIEN) participant 481˙582.00
8    BIOPOLIS SL

 Organization address address: CALLE CATEDRATICO AGUSTIN ESCARDINO 9
city: PATERNA VALENCIA
postcode: 46980

contact info
Titolo: Dr.
Nome: Marta
Cognome: Tortajada
Email: send email
Telefono: +34 963160299
Fax: +34 963160367

ES (PATERNA VALENCIA) participant 407˙404.00
9    ANAXOMICS BIOTECH, S.L.

 Organization address address: CALLE BALMES (PISO 4 - PTA 2A) 89
city: Barcelona
postcode: 8008

contact info
Titolo: Ms.
Nome: Vesna
Cognome: Radovanovic
Email: send email
Telefono: 34934516717

ES (Barcelona) participant 349˙200.00
10    JENABIOS GMBH: UMWELTBIOTECHNOLOGIEN & SERVICELEISTUNGEN

 Organization address address: Orlaweg 2
city: Jena
postcode: 7743

contact info
Titolo: Dr.
Nome: Katrin
Cognome: Scheibner
Email: send email
Telefono: +49 0357385957

DE (Jena) participant 348˙600.00
11    UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II.

 Organization address address: Corso Umberto I 40
city: NAPOLI
postcode: 80138

contact info
Titolo: Prof.
Nome: Giovanni
Cognome: Sannia
Email: send email
Telefono: +39 081674310
Fax: +39 081 674313

IT (NAPOLI) participant 333˙600.00
12    Setas Kimya Sanayi AS

 Organization address address: Karanfil sok 1.levent 18
city: Istanbul
postcode: 34330

contact info
Titolo: Dr.
Nome: Rezzan
Cognome: Karaaslan
Email: send email
Telefono: +90 2827581823

TR (Istanbul) participant 333˙265.00
13    CHIRACON GMBH

 Organization address address: BIOTECHNOLOGIEPARK TGZ 1
city: LUCKENWALDE
postcode: 14943

contact info
Titolo: Dr.
Nome: Ralf
Cognome: Zuhse
Email: send email
Telefono: +49 3371 681322
Fax: +49 3371 681295

DE (LUCKENWALDE) participant 319˙000.00
14    CLEA TECHNOLOGIES BV

 Organization address address: DELFTECHPARK 34
city: DELFT
postcode: 2628 HX

contact info
Titolo: Mr.
Nome: Ivo
Cognome: Van Der Laan
Email: send email
Telefono: +31 157600305

NL (DELFT) participant 250˙536.00
15    CHEMINOVA AS

 Organization address address: HARBOOREVEJ 78
city: HARBOORE
postcode: 7673

contact info
Titolo: Mr.
Nome: Ib
Cognome: Winckelmann
Email: send email
Telefono: +45 96909658

DK (HARBOORE) participant 199˙946.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

oxidation    reactions    enzymatic    industry    optimized    industrial    chemical    efficiency    optimization    indox    companies    biocatalysts    intermediates    oxidoreductases   

 Obiettivo del progetto (Objective)

The INDOX proposal on industrial oxidoreductases aims to provide relevant industrial case stories to demonstrate the efficacy of optimized biocatalysts on targeted reactions, and to establish the processes scalability, sustainability and cost-efficiency versus chemical conversion processes. The chemical industry (specialties excluded) is not yet embracing enzymatic oxidation reactions to a significant extent primarily due to lack of biocatalysts with the required selectivity, availability and compatibility with the rigorous process conditions. Selected industrial oxidation and oxyfunctionalization target reactions form the basis for the INDOX screening and optimization of new biocatalysts, including: i) Intermediates for agrochemicals/APIs; ii) Polymer precursors and functionalized polymers; and iii) Intermediates for dye-stuffs. The project flow comprises: i) Recovery of selective biocatalysts from the groups of heme-peroxidases/peroxygenases, flavo-oxidases and copper-oxidoreductases from fungal genomes and other sources; ii) Improvement of their oxidative activity and stability by protein engineering (using rational design, directed evolution and hybrid approaches combined with computational calculations) to fulfill the operational and catalytic conditions required by the chemical industry; and iii) Optimization of reaction conditions and reactor configurations (including immobilization technologies and new enzymatic cascade reactions). Finally the cost efficiency compared to chemical processing will be evaluated. The INDOX approach is supported by a highly-specialized consortium of SMEs, large companies and research/academic institutions. Production of the new optimized biocatalysts and their introduction into the chemical market will take advantage from the participation of the world-leading company in the sector of industrial enzymes, together with several chemical companies willing to implement the new medium- and large-scale biotransformation processes.

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