PNEUMONP

Nanotherapeutics to Treat Antibiotic Resistant Gram-Negative Pneumonia Infections

 Coordinatore FUNDACION CIDETEC 

 Organization address address: Parque Tecnologico de Miramon, Paseo Miramon 196
city: DONOSTIA - SAN SEBASTIAN
postcode: 20009

contact info
Titolo: Mr.
Nome: Jon
Cognome: Lacunza
Email: send email
Telefono: +34 943309022

 Nazionalità Coordinatore Spain [ES]
 Sito del progetto http://www.pneumonp.eu
 Totale costo 7˙529˙775 €
 EC contributo 5˙682˙351 €
 Programma FP7-NMP
Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies
 Code Call FP7-NMP-2013-LARGE-7
 Funding Scheme CP-IP
 Anno di inizio 2014
 Periodo (anno-mese-giorno) 2014-01-01   -   2017-12-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    FUNDACION CIDETEC

 Organization address address: Parque Tecnologico de Miramon, Paseo Miramon 196
city: DONOSTIA - SAN SEBASTIAN
postcode: 20009

contact info
Titolo: Mr.
Nome: Jon
Cognome: Lacunza
Email: send email
Telefono: +34 943309022

ES (DONOSTIA - SAN SEBASTIAN) coordinator 896˙660.00
2    ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM

 Organization address address: 's Gravendijkwal 230
city: ROTTERDAM
postcode: 3015CE

contact info
Titolo: Dr.
Nome: John
Cognome: Hays
Email: send email
Telefono: +31 107032177

NL (ROTTERDAM) participant 886˙960.40
3    UNIVERSITEIT UTRECHT

 Organization address address: Heidelberglaan 8
city: UTRECHT
postcode: 3584 CS

contact info
Titolo: Mr.
Nome: Martin
Cognome: De Geest
Email: send email
Telefono: +31 302532206

NL (UTRECHT) participant 516˙185.75
4    ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES

 Organization address address: PASEO MIRAMON PARQUE TECNOLOGICO DE SAN SEBASTIAN EDIFICIO EMPRESARIAL C 182
city: SAN SEBASTIAN
postcode: 20009

contact info
Titolo: Mr.
Nome: Alfonso
Cognome: Egaña
Email: send email
Telefono: 34943005300
Fax: 34943005301

ES (SAN SEBASTIAN) participant 499˙873.20
5    SETLANCE SRL

 Organization address address: VIA FIORENTINA 1 1
city: SIENA
postcode: 53100

contact info
Titolo: Dr.
Nome: Chiara
Cognome: Falciani
Email: send email
Telefono: 393393000000

IT (SIENA) participant 496˙893.20
6    FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V

 Organization address address: Hansastrasse 27C
city: MUENCHEN
postcode: 80686

contact info
Titolo: Ms.
Nome: Andrea
Cognome: Zeumann
Email: send email
Telefono: +49 89 1205 2723
Fax: +49 89 1205 7534

DE (MUENCHEN) participant 487˙281.66
7    PATHOFINDER BV

 Organization address address: RANDWYCKSINGEL 45 45
city: MAASTRICHT
postcode: 6229 EG

contact info
Titolo: Dr.
Nome: Guus
Cognome: Simons
Email: send email
Telefono: +31 433030400

NL (MAASTRICHT) participant 468˙893.20
8    INGENIATRICS TECNOLOGIAS S.L.

 Organization address address: CALLE CAMINO MOZARABE 41 PARQUE INDUSTRIAL PARQUE PLATA CAMAS
city: SEVILLA
postcode: 41900

contact info
Titolo: Ms.
Nome: Diana Beatriz
Cognome: Gomez Guerra
Email: send email
Telefono: +34 954081214

ES (SEVILLA) participant 468˙543.60
9    ADENIUM BIOTECH APS

 Organization address address: OLE MAALOESVEJ 3
city: KOBENHAVN
postcode: 2200

contact info
Titolo: Dr.
Nome: Peter
Cognome: Nordkild
Email: send email
Telefono: +45 25471646

DK (KOBENHAVN) participant 435˙200.00
10    EUROPEAN RESEARCH AND PROJECT OFFICE GMBH

 Organization address address: Science Park 1, Stuhlsatzenhausweg 69
city: SAARBRUECKEN
postcode: 66123

contact info
Titolo: Ms.
Nome: Corinna
Cognome: Hahn
Email: send email
Telefono: +49 68195923362
Fax: +49 68195923370

DE (SAARBRUECKEN) participant 342˙340.00
11    UMAPS COMMUNICATION SARL

 Organization address address: AVENUE DE LA RESISTANCE 104 112
city: MONTREUIL
postcode: 93100

contact info
Titolo: Mr.
Nome: Stéphane
Cognome: Nai Im Tholander
Email: send email
Telefono: +33 141729119

FR (MONTREUIL) participant 183˙520.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

combined    antibiotics    types    resistant    antimicrobial    kit    treatment    diagnostic    gram    caused    pulmonary    drug    bacteria    bacterial    pneumonp    therapy    infection    lungs    inhalable    negative    antibiotic    ncs    pneumonia    infections    lung    people   

 Obiettivo del progetto (Objective)

'The main objective of PneumoNP is the development of a theragnostic system for the treatment of lung Gram-negative bacterial infections. As a proof of concept PneumoNP will focus the attention on Klebsiella pneumoniae caused infections. A diagnostic kit will be developed to enable a rapid and precise identification of the bacteria strain causing the infection and avoid the use of wide spectrum antibiotics. For the treatment a nanotherapeutic based inhalable antibiotic will be developed. The therapeutic nanosystem will be based on a nanocarrier combined with an antimicrobial peptide. 3 different types of NCs will be tested with 2 AMPs to be able to obtain a novel effective inhalable antimicrobial NS. Nanotherapeutics offers many advantages in pulmonary drug-delivery, due to the huge surface area available in the lungs and their potential to achieve uniform distribution of drug dose among the alveoli. To improve this delivery to the lungs an aerosol system will also be developed. Due to the characteristics related to pulmonary delivery of NCs, topical and systemic bioavailabilities are envisaged. A diagnostic kit will be generated to monitor the efficacy and efficiency of the therapy. Once this treatment is proved to be effective, it could then be applied to any Gram-negative lung bacterial infection. The number of antibiotic resistant bacteria strains is increasing rapidly, new types of therapy are urgently required to avoid the use of standard antibiotics. Gram-negative bacteria that cause pneumonia are one of the main sources of nosocomial infections, mainly in people with a weakened immune system. Apart from pneumonia they can cause bacteremia and other infections. Early detection of the infection source combined with the development of appropriate and effective NSs to treat multi-drug resistant (MDR) bacteria caused infections will definitely radically improve the healing process of patients and avoid complications for people in hospital.'

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