CARDIORISK

The mechanisms of cardiovascular risks after low radiation doses

 Coordinatore KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN 

 Organization address address: ISMANINGER STRASSE 22
city: MUENCHEN
postcode: 81675

contact info
Titolo: Ms.
Nome: Claudia
Cognome: Speiser
Email: send email
Telefono: +49 89 28810416
Fax: +49 89 288104916

 Nazionalità Coordinatore Germany [DE]
 Sito del progetto http://www.cardiorisk.eu/
 Totale costo 6˙701˙454 €
 EC contributo 2˙859˙897 €
 Programma FP7-EURATOM-FISSION
EURATOM: Nuclear fission and radiation protection
 Code Call FP7-Fission-2007
 Funding Scheme CP
 Anno di inizio 2008
 Periodo (anno-mese-giorno) 2008-02-01   -   2011-06-30

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN

 Organization address address: ISMANINGER STRASSE 22
city: MUENCHEN
postcode: 81675

contact info
Titolo: Ms.
Nome: Claudia
Cognome: Speiser
Email: send email
Telefono: +49 89 28810416
Fax: +49 89 288104916

DE (MUENCHEN) coordinator 0.00
2    GABO:MI GESELLSCHAFT FUR ABLAUFORGANISATION:MILLIARIUM MBH & CO KG GAB O

 Organization address address: Oskar-von-Miller-Ring 29
city: MUENCHEN
postcode: 80333

contact info
Titolo: Ms.
Nome: Birgit
Cognome: Fuchs
Email: send email
Telefono: +4989288104 0
Fax: +4989288104 20

DE (MUENCHEN) participant 0.00
3    HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH

 Organization address address: Ingolstaedter Landstrasse 1
city: MUENCHEN
postcode: 85764

contact info
Titolo: Dr.
Nome: Juergen
Cognome: Ertel
Email: send email
Telefono: +49 89 3187 3022
Fax: +49 89 3187 2212

DE (MUENCHEN) participant 0.00
4    INSTITUT DE RADIOPROTECTION ET DE SURETE NUCLEAIRE

 Organization address address: Avenue de la Division Leclerc 31
city: FONTENAY AUX ROSES
postcode: 92260

contact info
Titolo: Dr.
Nome: Marie-Catherine
Cognome: Vozenin-Brotons
Email: send email
Telefono: 33142114283
Fax: 33142115236

FR (FONTENAY AUX ROSES) participant 0.00
5    MARIA SKLODOWSKA-CURIE MEMORIAL CANCER CENTER

 Organization address address: "Ul.W.K. Roentgena, 5"
city: WARZAWA
postcode: 2781

contact info
Titolo: Prof.
Nome: Piotr
Cognome: Widlak
Email: send email
Telefono: 48322789672
Fax: 48322313512

PL (WARZAWA) participant 0.00
6    QUEEN'S UNIVERSITY BELFAST

 Organization address address: University Road
city: BELFAST
postcode: BT7 1NN

contact info
Titolo: Ms.
Nome: Colleen
Cognome: Spence
Email: send email
Telefono: 442891000000
Fax: 442891000000

UK (BELFAST) participant 0.00
7    SATEILYTURVAKESKUS

 Organization address address: Laippatie 4
city: HELSINKI
postcode: 881

contact info
Titolo: Ms.
Nome: Jaana
Cognome: Mannonen
Email: send email
Telefono: 358976000000
Fax: 358976000000

FI (HELSINKI) participant 0.00
8    STICHTING HET NEDERLANDS KANKER INSTITUUT

 Organization address address: PLESMANLAAN 121
city: AMSTERDAM
postcode: 1066 CX

contact info
Titolo: Dr.
Nome: Henri
Cognome: Van Luenen
Email: send email
Telefono: 31205122097
Fax: 3131210000000

NL (AMSTERDAM) participant 0.00
9    TECHNISCHE UNIVERSITAET DRESDEN

 Organization address address: HELMHOLTZSTRASSE 10
city: DRESDEN
postcode: 1069

contact info
Titolo: Prof.
Nome: Wolfgang
Cognome: Dörr
Email: send email
Telefono: 493515000000
Fax: 493515000000

DE (DRESDEN) participant 0.00
10    THE UNIVERSITY OF SHEFFIELD

 Organization address address: FIRTH COURT WESTERN BANK
city: SHEFFIELD
postcode: S10 2TN

contact info
Titolo: Ms.
Nome: Gill
Cognome: Wells
Email: send email
Telefono: 44114221434
Fax: 441142000000

UK (SHEFFIELD) participant 0.00
11    UNIVERSITAET LEIPZIG

 Organization address address: RITTERSTRASSE 26
city: LEIPZIG
postcode: 4109

contact info
Titolo: Mr.
Nome: Ulrich
Cognome: Roessler
Email: send email
Telefono: 493420000000
Fax: 493420000000

DE (LEIPZIG) participant 0.00
12    UNIVERSITAET ROSTOCK

 Organization address address: UNIVERSITATSPLATZ 1
city: ROSTOCK
postcode: 18051

contact info
Titolo: Ms.
Nome: Margitta
Cognome: Paucker
Email: send email
Telefono: 493815000000
Fax: 493815000000

DE (ROSTOCK) participant 0.00
13    UNIVERSITEIT MAASTRICHT

 Organization address address: Minderbroedersberg 4-6
city: MAASTRICHT
postcode: 6200 MD

contact info
Titolo: Mr.
Nome: Rob
Cognome: Van Der Zander
Email: send email
Telefono: 31433881647
Fax: 31433670916

NL (MAASTRICHT) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

arteries    induced    vivo    pathogenesis    disease    cardiovascular    cardiac    function    alteration    radiation    atherosclerotic    perfusion    lesions    exposure    moderate    doses    heart    addition    molecular   

 Obiettivo del progetto (Objective)

'Recent epidemiologic evidence suggests that moderate and low radiation doses to the heart may result in a moderate, but significant increase in cardiovascular mortality. So far, the pathogenesis of radiation induced heart disease has not been studied in detail. Pathohistologic studies suggest that microvascular damage plays a crucial role in the development of radiation induced cardiovascular disease. In addition, radiation may increase atherosclerotic lesions in the coronary arteries. The aim of this collaborative research project is to elucidate the pathogenesis of early and late alteration in the microcirculation of the heart and of atherosclerotic lesions in arteries after exposure to low radiation doses in comparison to high radiation doses. A major goal will be the investigation of early molecular, proinflammatory and prothrombotic changes as well as perfusion alteration, cardiac cell integrity and immunologic influences. To achieve this goal, in vivo as well as ex vivo and in vitro studies will be performed. A central component of the project will be the local irradiation of the heart with subsequent isolation of cardiomyocytes and cardiac endothelial cells to provide all participating groups with the same biological material for further study. In addition, structural, morphological and molecular studies will be complemented by functional assays and imaging methods.'

Introduzione (Teaser)

Understanding the impact of radiation on cardiac function is vital for taking appropriate precautions to minimise exposure. The CARDIORISK initiative investigated the pathogenic mechanisms following radiation that affect myocardial perfusion and vascularisation, stress response and cardiac function.

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