SYSINBIO

Systems Biology as a Driver for Industrial Biotechnology

 Coordinatore CHALMERS TEKNISKA HOEGSKOLA AB 

 Organization address address: -
city: GOETEBORG
postcode: 41296

contact info
Titolo: Ms.
Nome: Karin
Cognome: Westerlund
Email: send email
Telefono: -7723195
Fax: -161958

 Nazionalità Coordinatore Sweden [SE]
 Sito del progetto http://www.sysbio.se/SYSINBIO
 Totale costo 1˙485˙204 €
 EC contributo 996˙545 €
 Programma FP7-KBBE
Specific Programme "Cooperation": Food, Agriculture and Biotechnology
 Code Call FP7-KBBE-2007-1
 Funding Scheme CSA-CA
 Anno di inizio 2008
 Periodo (anno-mese-giorno) 2008-12-01   -   2011-11-30

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    CHALMERS TEKNISKA HOEGSKOLA AB

 Organization address address: -
city: GOETEBORG
postcode: 41296

contact info
Titolo: Ms.
Nome: Karin
Cognome: Westerlund
Email: send email
Telefono: -7723195
Fax: -161958

SE (GOETEBORG) coordinator 0.00
2    BASF SE

 Organization address address: CARL BOSCH STRASSE 38
city: LUDWIGSHAFEN AM RHEIN
postcode: 67056

contact info
Titolo: Dr.
Nome: Hartwig
Cognome: Schroeder
Email: send email
Telefono: -6043174
Fax: -6053380

DE (LUDWIGSHAFEN AM RHEIN) participant 0.00
3    BOGAZICI UNIVERSITESI

 Organization address address: BEBEK
city: ISTANBUL
postcode: 34342

contact info
Titolo: Prof.
Nome: Betul
Cognome: Kirdar
Email: send email
Telefono: -3597248
Fax: -2872582

TR (ISTANBUL) participant 0.00
4    CHR. HANSEN A/S

 Organization address address: Boege Alle 10-12
city: HOERSHOLM
postcode: 2970

contact info
Titolo: Dr.
Nome: Hans
Cognome: Van Den Brink
Email: send email
Telefono: -45748410
Fax: -45748949

DK (HOERSHOLM) participant 0.00
5    DANMARKS TEKNISKE UNIVERSITET

 Organization address address: Anker Engelundsvej 1, Building 101A
city: KONGENS LYNGBY
postcode: 2800

contact info
Titolo: Ms.
Nome: Trine
Cognome: Bro
Email: send email
Telefono: -7175
Fax: -8691

DK (KONGENS LYNGBY) participant 0.00
6    DSM FOOD SPECIALTIES BV

 Organization address address: ALEXANDER FLEMINGLAAN 1
city: DELFT
postcode: 2613 AX

contact info
Titolo: Dr.
Nome: Herman
Cognome: Pel
Email: send email
Telefono: -2792687
Fax: -2792474

NL (DELFT) participant 0.00
7    ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE

 Organization address address: BATIMENT CE 3316 STATION 1
city: LAUSANNE
postcode: 1015

contact info
Titolo: Prof.
Nome: Vassily
Cognome: Hatzimanikatis
Email: send email
Telefono: -6939850
Fax: -6939855

CH (LAUSANNE) participant 0.00
8    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZURICH

 Organization address address: Raemistrasse 101
city: ZUERICH
postcode: 8092

contact info
Titolo: Dr.
Nome: Matthias
Cognome: Heinemann
Email: send email
Telefono: -6326369
Fax: -6331054

CH (ZUERICH) participant 0.00
9    EVONIK DEGUSSA GmbH

 Organization address address: Rellinghauser Str. 1-11
city: Essen
postcode: 45128

contact info
Titolo: Dr.
Nome: Ralf
Cognome: Takors
Email: send email
Telefono: -7118451
Fax: -7118664

DE (Essen) participant 0.00
10    FLUXOME SCIENCES A/S

 Organization address address: GYMNASIEVEJ 5
city: STENLOSE
postcode: 3660

contact info
Titolo: Dr.
Nome: Jochen
Cognome: Förster
Email: send email
Telefono: -88708376
Fax: -88708358

DK (STENLOSE) participant 0.00
11    LUNDS UNIVERSITET

 Organization address address: Paradisgatan 5c
city: LUND
postcode: 22100

contact info
Titolo: Prof.
Nome: Olov
Cognome: Sterner
Email: send email
Telefono: -2228213
Fax: -2220340

SE (LUND) participant 0.00
12    METABOLIC EXPLORER SA

 Organization address address: BIOPOLE CLERMONT LIMAGNE
city: SAINT BEAUZIRE
postcode: 63360

contact info
Titolo: Mr.
Nome: Paul
Cognome: Michalet
Email: send email
Telefono: -73334275
Fax: -73334272

FR (SAINT BEAUZIRE) participant 0.00
13    NOVOZYMES A/S

 Organization address address: Krogshoejvej 36
city: BAGSVAERD
postcode: 2880

contact info
Titolo: Dr.
Nome: Carsten
Cognome: Hjort
Email: send email
Telefono: -44426211
Fax: -44980201

DK (BAGSVAERD) participant 0.00
14    STIFTELSEN FRAUNHOFER-CHALMERS CENTRUM FOR INDUSTRIMATEMATIK

 Organization address address: Chalmers Science Park
city: GOETEBORG
postcode: 41288

contact info
Titolo: Dr.
Nome: Mats
Cognome: Jirstrand
Email: send email
Telefono: -7724235
Fax: -7724245

SE (GOETEBORG) participant 0.00
15    TECHNISCHE UNIVERSITEIT DELFT

 Organization address address: Stevinweg 1
city: DELFT
postcode: 2628 CN

contact info
Titolo: Mr.
Nome: Rogier Willem
Cognome: Van Loghem
Email: send email
Telefono: -2789679
Fax: -2784285

NL (DELFT) participant 0.00
16    TEKNOLOGIAN TUTKIMUSKESKUS VTT

 Organization address address: TEKNIIKANTIE 4 A
city: ESPOO
postcode: 02044 VTT

contact info
Titolo: Prof.
Nome: Merja
Cognome: Penttilä
Email: send email
Telefono: +35820722 4504
Fax: 358207000000

FI (ESPOO) participant 0.00
17    UNIVERSIDADE DO MINHO

 Organization address address: Largo do Paco
city: BRAGA
postcode: 4704553

contact info
Titolo: Dr.
Nome: Adriana
Cognome: Carvalho
Email: send email
Telefono: -604402
Fax: -676074

PT (BRAGA) participant 0.00
18    UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA

 Organization address address: PIAZZA DELL'ATENEO NUOVO 1
city: MILANO
postcode: IT-20126

contact info
Titolo: Dr.
Nome: Anastasia
Cognome: Sguera
Email: send email
Telefono: -64483716
Fax: -64483532

IT (MILANO) participant 0.00
19    UNIVERSITAET DES SAARLANDES

 Organization address address: CAMPUS
city: SAARBRUECKEN
postcode: 66041

contact info
Titolo: Ms.
Nome: Mareike
Cognome: Schmitt
Email: send email
Telefono: -95923998
Fax: -95924002

DE (SAARBRUECKEN) participant 0.00
20    UNIVERSITAET SIEGEN

 Organization address address: HERRENGARTEN 3
city: SIEGEN
postcode: 57072

contact info
Titolo: Dr.
Nome: Iris
Cognome: Körver
Email: send email
Telefono: -7405068
Fax: -7405183

DE (SIEGEN) participant 0.00
21    UNIVERSITAET STUTTGART

 Organization address address: Keplerstrasse 7
city: STUTTGART
postcode: 70174

contact info
Titolo: Prof.
Nome: Matthias
Cognome: Reuss
Email: send email
Telefono: xx711-685-64573
Fax: xx-711-685-65164

DE (STUTTGART) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

recent    enhanced    coordinate    genetic    years    appropriate    sysinbio    model    education    biology    models    cell    silico    perform    industry    tools    database    industrial    science    industrially    metabolic    fluxomics    modifications    biotechnology    simulation    factories    mathematical    analytical    cells    metabolomics    identification    training    engineering    ones   

 Obiettivo del progetto (Objective)

'Metabolic engineering is an applied science focusing on developing new cell factories or improving existing ones. Metabolic engineering is an enabling science, and distinguishes itself from applied genetic engineering by the use of advanced analytical tools for identification of appropriate targets for genetic modifications and the use of mathematical models to perform in silico design of optimized cell factories. In recent years, there has been increasing focus on using mathematical models for design. SYSIBIO will coordinate European activities in the field of model driven metabolic engineering and also coordination of activities on other technologies required for state of the art metabolic engineering, e.g. metabolomics and fluxomics. The coordination of activities will involve establishing a database containing metabolic models for different industrially important microorganisms. The database will also contain different simulation tools required for use of these models to identify metabolic engineering targets and use of these models for analysis of omics data. SYSINBIO will also coordinate the further development of techniques required for metabolic engineering, such as metabolomics, fluxomics and identification of mutations in evolved strains. Furthermore, an important part of SYSINBIO will be coordination of education and training in the field of metabolic engineering in Europe.'

Introduzione (Teaser)

One day soon metabolic engineering could revolutionise the chemical industry. To push Europe to the forefront of the technology, an EU-funded project is coordinating research activities.

Descrizione progetto (Article)

Metabolic engineering is the practice of optimising genetic and regulatory processes within cells to increase the cells' production of a certain substance. It is an applied science focusing on either developing new cell factories or improving existing ones. It uses advanced analytical tools to identify appropriate targets for genetic modifications and mathematical models to perform in silico design of optimised cell factories used in industrial biotechnology.

With the focus on using mathematical models for design increasing in recent years, the EU-funded 'Systems biology as a driver for industrial biotechnology' (Sysinbio) project is now coordinating European efforts. Sysinbio's lead role in Europe's model-driven metabolic engineering activities has led to the creation of the BioMet ToolBox database. This contains metabolic models for different, industrially important micro-organisms and various simulation tools.

Sysinbio is currently developing new and better mathematical models of metabolism that can be used for metabolic engineering. Activities on both stoichiometric (of reactants) models and kinetic (energy produced by motion) models have already been coordinated.

So far, the project team has shown that coordination of the development of more reliable and standardised microbial models has enhanced model predictions. This has enabled the application of simulation and optimisation algorithms that can identify gene modifications that can increase the production yields of target compounds.

Another important part of Sysinbio has been the coordination of education and training in the field of metabolic engineering in Europe. This has resulted in support for students participating at key conferences and the organisation of various dedicated courses on systems biology.

The project results are expected to have a significant long-term impact on improving the competiveness of European industrial biotechnology. Benefits will include improved dialogue between academia and industry, better training for researchers, and the provision of enhanced standards and methods for use in industrial biotechnology.

Altri progetti dello stesso programma (FP7-KBBE)

FISHPOPTRACE (2008)

Fish Population Structure and Traceability

Read More  

ANIMPOL (2010)

Biotechnological conversion of carbon containing wastes for eco-efficient production of high added value products

Read More  

ISA-PACK (2012)

"A Flexible Sustainable Active and Intelligent Packaging Technology Platform Enabling Enhanced Shelf Life, Quality and Safety of Fresh Food Produce"

Read More