EIMID-IAPP

European Initiative for basic research in Microbiology and Infectious Diseases - IAPP

 Coordinatore GLAXOSMITHKLINE VACCINES SRL 

 Organization address address: Via Fiorentina 1
city: SIENA
postcode: 53100

contact info
Titolo: Dr.
Nome: John Laird
Cognome: Telford
Email: send email
Telefono: +39 0577 243470
Fax: +39 0577 243564

 Nazionalità Coordinatore Italy [IT]
 Totale costo 2˙172˙806 €
 EC contributo 2˙172˙806 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-2007-3-1-IAPP
 Funding Scheme MC-IAPP
 Anno di inizio 2008
 Periodo (anno-mese-giorno) 2008-12-01   -   2012-11-30

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    GLAXOSMITHKLINE VACCINES SRL

 Organization address address: Via Fiorentina 1
city: SIENA
postcode: 53100

contact info
Titolo: Dr.
Nome: John Laird
Cognome: Telford
Email: send email
Telefono: +39 0577 243470
Fax: +39 0577 243564

IT (SIENA) coordinator 0.00
2    IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE

 Organization address address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD
city: LONDON
postcode: SW7 2AZ

contact info
Titolo: Mr.
Nome: Michael
Cognome: Robinson
Email: send email
Telefono: +44 207 594 3866
Fax: +44 207 594 3868

UK (LONDON) participant 0.00
3    INSTITUT PASTEUR

 Organization address address: RUE DU DOCTEUR ROUX 25-28
city: PARIS CEDEX 15
postcode: 75724

contact info
Titolo: Prof.
Nome: Philippe
Cognome: Sansonetti
Email: send email
Telefono: +33 1 4568 8342
Fax: +33 1 4568 8953

FR (PARIS CEDEX 15) participant 0.00
4    KAROLINSKA INSTITUTET

 Organization address address: Nobels Vag 5
city: STOCKHOLM
postcode: 17177

contact info
Titolo: Dr.
Nome: Christina
Cognome: Bergehed-Bonnevier
Email: send email
Telefono: +46 8 524 871 40
Fax: +46 8 302566

SE (STOCKHOLM) participant 0.00
5    MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.

 Organization address address: Hofgartenstrasse 8
city: MUENCHEN
postcode: 80539

contact info
Titolo: Prof.
Nome: Thomas
Cognome: Meyer
Email: send email
Telefono: +49 30 28460 400
Fax: +49 30 28460 401

DE (MUENCHEN) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

years    virulence    informal    industrial    academia    researcher    vaccines    drug    infectious    iapp    emphasis    steering    efficient    acquire    infections    series    mucosal    seconded    diseases    proteins    affecting    infection    complementary    eimid    constant    technologies    vaccine    bacterial    therapeutic    basic    levels    academic    exchange    scientists    surfaces    therapies    microbiology    industry    versa    transfer    area    doctoral    annual    vice    survival    meetings    expertise    yielded   

 Obiettivo del progetto (Objective)

'The EIMID-IAPP training programme is part of the European Initiative for Basic Research in Microbiology and Infectious Diseases (EIMID), created in 2003 by scientists of five European centres of excellence (the Max Planck Institute for Infection Biology in Berlin, the CMMI at Imperial College in London, the Institut Pasteur in Paris, the Karolinska Institutet in Stockholm; and the vaccine company Novartis in Siena). By building a strong coalition among these institutes, EIMID aims at setting the basis for a future no-wall European Institute of Microbiology and Infectious Diseases, as part of the European Research Area (ERA). EIMID-IAPP aims at implementing the Industry-Academia cooperation through an integrated programme of exchange of young researchers between the industrial partner and the four academic institutions. The goal of the collaborative project is the development of Novel Therapeutic Approaches against Infectious Diseases, with particular emphasis to drug-based and vaccine-based therapies for bacterial infections affecting mucosal surfaces. Four researchers will be seconded from the industrial partner to the four academic institutions and vice-versa. Each secondment will be for two years (with a six month intermission for intermediate knowledge transfer to the mother institution), and the seconded staff between two institutions will investigate complementary aspects of the same project sub-area. Each institution will also recruit an experienced researcher for two years, to acquire new expertise and technologies necessary to the project development. A series of informal discussions, and annual general meetings, will allow constant exchange of information and efficient project steering. This activity of Industry-Academia exchange fulfils the EIMID goals of 1) harmonising European research programmes, so as to achieve a critical mass on relevant topics. 2) fostering exchange of scientists, particularly at the doctoral and post-doctoral levels.'

Introduzione (Teaser)

With the fast-spreading nature of infectious diseases, it has become an EU imperative to encourage more in-depth research and novel approaches to vaccines.

Descrizione progetto (Article)

The EU-funded 'European initiative for basic research in microbiology and infectious diseases' (EIMID-IAPP) programme aimed to promote the development of novel therapeutic approaches against infectious diseases. This was undertaken with particular emphasis on drug-based and vaccine-based therapies for bacterial infections affecting mucosal surfaces.

In order to gain fresh insight, four researchers were transferred from the project's industrial partners to its academic partners and vice versa. Each transfer yielded thorough investigations and complementary research.

Each academic institution also recruited an experienced researcher for two years in order to acquire new expertise and technologies necessary for project development. A series of informal discussions and annual general meetings also allowed for a constant exchange of information and efficient project steering.

The scientific work-plan was divided into two areas. The first concentrated on discovering key antigens that are essential for infection. The second focused on identifying key bacterial genes essential for survival, growth, colonisation and virulence expression in vivo.

One topic examined during the project was gene regulation in Shigella. The objective was to understand the mechanisms governing survival and virulence in the lower intestine. Several proteins that control the transport of proteins to the bacterial surface were shown to be affected by low oxygen levels.

http://www.eimid.org/projects/iapp/index.html (EIMID-IAPP) has yielded a number of insights into how mucosal pathogens cause disease, which could aid in the development or improvement of drugs and vaccines. Furthermore, the close interactions between academia and industry have led to lasting collaborations that should strengthen the field of microbiology in Europe.

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