MALSIG

Signalling in life cycle stages of malaria parasites

 Coordinatore  

 Organization address address: 101 Rue de Tolbiac
city: PARIS
postcode: 75654

contact info
Titolo: Ms.
Nome: Rofigua
Cognome: Hakem
Email: send email
Telefono: +33 3 20 29 93 73
Fax: +33 3 20 49 01 38

 Nazionalità Coordinatore Non specificata
 Totale costo 4˙078˙878 €
 EC contributo 3˙000˙000 €
 Programma FP7-HEALTH
Specific Programme "Cooperation": Health
 Code Call FP7-HEALTH-200
 Anno di inizio 2009
 Periodo (anno-mese-giorno) 2009-02-01   -   2012-07-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)

 Organization address address: 101 Rue de Tolbiac
city: PARIS
postcode: 75654

contact info
Titolo: Ms.
Nome: Rofigua
Cognome: Hakem
Email: send email
Telefono: +33 3 20 29 93 73
Fax: +33 3 20 49 01 38

FR (PARIS) coordinator 472˙000.00
2    MEDICAL RESEARCH COUNCIL

 Organization address address: NORTH STAR AVENUE POLARIS HOUSE
city: SWINDON
postcode: SN2 1FL

contact info
Titolo: Ms.
Nome: Michele
Cognome: Marron
Email: send email
Telefono: +44 20 88162275
Fax: +44 20 889064477

UK (SWINDON) participant 332˙000.00
3    UNIVERSITY OF GLASGOW

 Organization address address: University Avenue
city: GLASGOW
postcode: G12 8QQ

contact info
Titolo: Mr.
Nome: Joe
Cognome: Galloway
Email: send email
Telefono: +44 141 330 3884
Fax: +44 141 330 5611

UK (GLASGOW) participant 332˙000.00
4    INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY

 Organization address address: PADRICIANO 99
city: TRIESTE
postcode: 34149

contact info
Titolo: Dr.
Nome: Chetan
Cognome: Chitnis
Email: send email
Telefono: +91 11 26742895
Fax: +91 11 267742895

IT (TRIESTE) participant 180˙000.00
5    BERNHARD-NOCHT-INSTITUT FUER TROPENMEDIZIN

 Organization address address: BERNHARD NOCHT STRASSE 74
city: HAMBURG
postcode: 20359

contact info
Titolo: Dr.
Nome: Volker Theo
Cognome: Heussler
Email: send email
Telefono: 4942818485
Fax: 4942818512

DE (HAMBURG) participant 166˙000.00
6    GENOME RESEARCH LIMITED

 Organization address address: THE GIBBS BUILDING, EUSTON ROAD 215
city: LONDON
postcode: NW1 2BE

contact info
Titolo: Ms.
Nome: Elisabeth
Cognome: Muller
Email: send email
Telefono: +44 1223 494969
Fax: +44 1223 494919

UK (LONDON) participant 166˙000.00
7    ISTITUTO SUPERIORE DI SANITA

 Organization address address: Viale Regina Elena 299
city: ROMA
postcode: 161

contact info
Titolo: Ms.
Nome: Rosa Maria
Cognome: Martoccia
Email: send email
Telefono: +39 06 49902688
Fax: +39 06 49903007

IT (ROMA) participant 166˙000.00
8    JULIUS-MAXIMILIANS UNIVERSITAET WUERZBURG

 Organization address address: SANDERRING 2
city: WUERZBURG
postcode: 97070

contact info
Nome: Christian
Cognome: Gloggengiesser
Email: send email
Telefono: +49 931 312294
Fax: +49 931 317180

DE (WUERZBURG) participant 166˙000.00
9    LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE

 Organization address address: KEPPEL STREET
city: LONDON
postcode: WC1E7HT

contact info
Titolo: Ms.
Nome: Penny
Cognome: Ireland
Email: send email
Telefono: +44 0 20 79272678
Fax: +44 0 20 75805636

UK (LONDON) participant 166˙000.00
10    ST GEORGE'S HOSPITAL MEDICAL SCHOOL

 Organization address address: Cranmer Terrace
city: LONDON
postcode: SW17 0RE

contact info
Titolo: Ms.
Nome: Susan
Cognome: Mcpheat
Email: send email
Telefono: +44 208 266 6818
Fax: +44 208 725 3426

UK (LONDON) participant 166˙000.00
11    STICHTING BIOMEDICAL PRIMATE RESEARCH CENTER

 Organization address address: LANGE KLEIWEG 161
city: RIJSWIJK ZH
postcode: 2288 GJ

contact info
Titolo: Mr.
Nome: Willem
Cognome: Slingerland
Email: send email
Telefono: +31 15 284 2500
Fax: +31 15 284 2600

NL (RIJSWIJK ZH) participant 166˙000.00
12    STICHTING KATHOLIEKE UNIVERSITEIT

 Organization address address: GEERT GROOTEPLEIN NOORD 9
city: NIJMEGEN
postcode: 6525 EZ

contact info
Titolo: Mr.
Nome: Peter
Cognome: Van Woensel
Email: send email
Telefono: +31 243610759
Fax: +31 243619395

NL (NIJMEGEN) participant 166˙000.00
13    INDIAN INSTITUTE OF SCIENCE

 Organization address address: CROSS MALLESHWARAM 18
city: BANGALORE
postcode: 560012

contact info
Titolo: Prof.
Nome: Utpal
Cognome: Tatu
Email: send email
Telefono: 9945567901

IN (BANGALORE) participant 90˙000.00
14    JAWAHARLAL NEHRU UNIVERSITY

 Organization address address: New Mehrouli Road
city: NEW DELHI
postcode: 110 067

contact info
Titolo: Dr.
Nome: Suman
Cognome: Dhar
Email: send email
Telefono: +91 11 26742572
Fax: +91 11 26741781

IN (NEW DELHI) participant 90˙000.00
15    NATIONAL INSTITUTE OF IMMUNOLOGY SOCIETY

 Organization address address: ARUNA ASAF ALI MARG
city: NEW DELHI
postcode: 110067

contact info
Titolo: Prof.
Nome: Avadhesha
Cognome: Surolia
Email: send email
Telefono: +91 11 26717102
Fax: +91 11 26717104

IN (NEW DELHI) participant 90˙000.00
16    INSTITUT PASTEUR

 Organization address address: RUE DU DOCTEUR ROUX 25-28
city: PARIS CEDEX 15
postcode: 75724

contact info
Titolo: Dr.
Nome: Nadia
Cognome: Khelef
Email: send email
Telefono: +33 1 40 61 33 78
Fax: +33 1 40 61 39 40

FR (PARIS CEDEX 15) participant 86˙000.00
17    UNIVERSITAETSKLINIKUM HEIDELBERG

 Organization address address: IM NEUENHEIMER FELD 672
city: HEIDELBERG
postcode: 69120

contact info
Titolo: Mr.
Nome: Thorsten
Cognome: Brietz
Email: send email
Telefono: 0049 6221 567086
Fax: 0049 6221 565460

DE (HEIDELBERG) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

proliferation    life    indian    pathways    infection    invasion    cycle    parasites    signal    transduction    signalling    transmission    biology    malaria    india    parasite   

 Obiettivo del progetto (Objective)

'Malaria is a major public health problem in the developing world and is endemic in many regions of India. The development of novel strategies for malaria control requires a better understanding of the biology of malaria parasites. Our project aims at bringing a significant contribution to this field, through dissecting the signalling pathways that regulate essential processes in the life cycle of malaria parasites. The proposed research will merge two lines of investigation that have thus far been conducted largely independently from each other, namely: (i) the characterisation of components of signal transduction pathways (protein kinases, nucleotide cyclases, calcium signalling mediators) in malaria parasites; (ii) the study of specific biological processes during the life cycle of malaria parasites. Merging these two fields of malaria research will ensure a high level of complementarity and synergy within the consortium. Specific workpackages will be centred on understanding signalling-dependent regulation in the following processes and stage transition within the life cycle of malaria parasites: • erythrocyte infection (invasion, parasite proliferation) • sexual development (gametocytogenesis, gametogenesis, transmission to the mosquito vector) • hepatocyte infection (invasion, parasite proliferation, egress) • membrane dynamics (trafficking, transporters) Approaches will include proteomics, reverse genetics, structural biology, and the use of animal models of malaria. The consortium is constituted of EU and Indian partners with a proven track record either in research into one of the developmental stages/processes described above, or in signal transduction in malaria parasites. The project will significantly strenghten EU-India cooperation in this highly relevant topic.'

Introduzione (Teaser)

European and Indian researchers teamed up to study the signalling pathways necessary for the survival and transmission of the malaria-causing parasite (Plasmodium falciparum). Some of the molecules detected could potentially serve as future targets for therapeutic intervention.

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