OBELIX

OBesogenic Endocrine disrupting chemicals: LInking prenatal eXposure to the development of obesity later in life

 Coordinatore STICHTING VU-VUMC 

 Organization address address: DE BOELELAAN 1105
city: AMSTERDAM
postcode: 1081 HV

contact info
Titolo: Dr.
Nome: Yvonne
Cognome: Kops
Email: send email
Telefono: +31 20 5987304
Fax: +31 20 5989950

 Nazionalità Coordinatore Netherlands [NL]
 Sito del progetto http://www.theobelixproject.org
 Totale costo 3˙918˙991 €
 EC contributo 2˙999˙692 €
 Programma FP7-KBBE
Specific Programme "Cooperation": Food, Agriculture and Biotechnology
 Code Call FP7-KBBE-2008-2B
 Funding Scheme CP-FP
 Anno di inizio 2009
 Periodo (anno-mese-giorno) 2009-05-01   -   2013-11-30

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    STICHTING VU-VUMC

 Organization address address: DE BOELELAAN 1105
city: AMSTERDAM
postcode: 1081 HV

contact info
Titolo: Dr.
Nome: Yvonne
Cognome: Kops
Email: send email
Telefono: +31 20 5987304
Fax: +31 20 5989950

NL (AMSTERDAM) coordinator 980˙064.00
2    RIJKSINSTITUUT VOOR VOLKSGEZONDHEIDEN MILIEU*NATIONAL INSTITUTEFOR PUBLIC HEALTH AND THE ENVIRONMENTEN

 Organization address address: Antonie Van Leeuwenhoeklaan 9
city: BILTHOVEN
postcode: 3721 MA

contact info
Titolo: Mr.
Nome: Remco
Cognome: Van Den Dikkenberg
Email: send email
Telefono: +31 30 274 2681
Fax: +31 30 274 4446

NL (BILTHOVEN) participant 808˙460.00
3    VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.

 Organization address address: Boeretang 200
city: MOL
postcode: 2400

contact info
Titolo: Prof.
Nome: Greet
Cognome: Schoeters
Email: send email
Telefono: 3214335200

BE (MOL) participant 616˙895.00
4    NASJONALT FOLKEHELSEINSTITUTT

 Organization address address: Lovisenberggata 8
city: OSLO
postcode: 403

contact info
Titolo: Mr.
Nome: Frederik
Cognome: Froen
Email: send email
Telefono: +47 21 07 7000
Fax: +47 21 07 78252

NO (OSLO) participant 264˙138.00
5    SLOVENSKA ZDRAVOTNICKA UNIVERZITA V BRATISLAVE

 Organization address address: LIMBOVA 12
city: BRATISLAVA
postcode: 83303

contact info
Titolo: Ms.
Nome: Milan
Cognome: Cagan
Email: send email
Telefono: +421 2 5930650
Fax: +421 2 5930652

SK (BRATISLAVA) participant 200˙000.00
6    INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE

 Organization address address: Rue De L'Universite 147
city: PARIS CEDEX 07
postcode: 75338

contact info
Titolo: Mr.
Nome: Jean-Jacques
Cognome: Petitdidier
Email: send email
Telefono: +33 142759276
Fax: +33 144087276

FR (PARIS CEDEX 07) participant 101˙047.00
7    STICHTING ECOBABY

 Organization address address: Hollandstraat 6
city: Loenersloot
postcode: 3634 AT

contact info
Titolo: Dr.
Nome: Aart
Cognome: Blom
Email: send email
Telefono: +31 20 6797938
Fax: +31 294 291373

NL (Loenersloot) participant 29˙088.00
8    VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG

 Organization address address: De Boelelaan 1105
city: AMSTERDAM
postcode: 1081 HV

contact info
Titolo: Ms.
Nome: Margot
Cognome: Rijerse
Email: send email
Telefono: +31 20 59 89 561
Fax: +31 20 59 89 553

NL (AMSTERDAM) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

classes    hazard    related    health    food    contaminant    prenatal    data    obesity    exposure    obesogenic    models    life    edcs    perform    risk    obelix    later    mechanisms    inducers    effect    childhood   

 Obiettivo del progetto (Objective)

'The incidence of childhood obesity has reached ‘epidemic’ proportions globally and there is an urgent need to increase our understanding of the impact of food contaminants on obesity development. The OBELIX project will examine the hypothesis that prenatal exposure to endocrine disrupting compounds (EDCs) in food plays a role in the development of obesity later in life. OBELIX proposes a multidisciplinary approach that combines epidemiology, neonatology, endocrinology, toxicology, analytical chemistry and risk assessment to address the objectives of the project: 1) To assess prenatal exposure in humans to major classes of EDCs in food identified as potential inducers of obesity (i.e. dioxins, non- and dioxin-like polychlorinated biphenyls, brominated flame retardants, phthalates and perfluorinated alkyl acids) using mother-child cohorts from four European regions with different food contaminant exposure patterns; 2) To relate early life exposure to EDCs with clinical markers, novel biomarkers and health effect data related to obesity; 3) To perform hazard characterization of in utero exposure to EDCs for the development of obesity later in life, using dose-response analysis in a rodent model; 4) To determine mechanisms of action of obesogenic EDCs on developmental programming with genomics and epigenetic analysis in in vivo and in vitro models; and, 5) to perform risk assessment of prenatal exposure to obesogenic EDCs in food, by integrating maternal exposure through food, contaminant exposure and health effect data in children, and hazard data. The outcomes of OBELIX are of particular relevance to the Work Programme, as the proposed project will generate new knowledge about prenatal exposure to major classes of EDCs in food that are potential inducers of obesity and related metabolic diseases later in life. It will also contribute new knowledge about effects of early exposure to EDCs on human health, including causality in animal models and possible mechanisms.'

Introduzione (Teaser)

A growing body of evidence points to the possibility that the origins of childhood obesity may be present before birth. A European research project explored the prenatal factors behind this relatively new phenomenon.

Altri progetti dello stesso programma (FP7-KBBE)

FERTIPLUS (2011)

FERTIPLUS Reducing mineral fertilisers and agro-chemicals by recycling treated organic waste as compost and bio-char products

Read More  

TERIFIQ (2012)

"Combining Technologies to achieve significant binary Reductions in Sodium, Fat and Sugar content in everyday foods whilst optimising their nutritional Quality"

Read More  

ADVANZ (2012)

ADVANZ - Advocacy for the fight against Neglected Zoonotic Diseases

Read More