INFRAVEC

Research capacity for the implementation of genetic control of mosquitoes

 Coordinatore IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE 

 Organization address address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD
city: LONDON
postcode: SW7 2AZ

contact info
Titolo: Ms.
Nome: Brooke
Cognome: Alasya
Email: send email
Telefono: +44 207 594 1181
Fax: +44 207 594 1418

 Nazionalità Coordinatore United Kingdom [UK]
 Totale costo 10˙782˙699 €
 EC contributo 8˙499˙618 €
 Programma FP7-INFRASTRUCTURES
Specific Programme "Capacities": Research infrastructures
 Code Call FP7-INFRASTRUCTURES-2008-1
 Funding Scheme CP-CSA-Infra
 Anno di inizio 2009
 Periodo (anno-mese-giorno) 2009-09-01   -   2014-02-28

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE

 Organization address address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD
city: LONDON
postcode: SW7 2AZ

contact info
Titolo: Ms.
Nome: Brooke
Cognome: Alasya
Email: send email
Telefono: +44 207 594 1181
Fax: +44 207 594 1418

UK (LONDON) coordinator 2˙488˙550.00
2    UNIVERSITA DEGLI STUDI DI PERUGIA

 Organization address address: PIAZZA DELL' UNIVERSITA 1
city: PERUGIA
postcode: 6123

contact info
Titolo: Prof.
Nome: Rosario
Cognome: Donato
Email: send email
Telefono: +39 07 55857400
Fax: +39 07 55857400

IT (PERUGIA) participant 1˙072˙677.44
3    ISTITUTO SUPERIORE DI RICERCA E FORMAZIONE SUI MATERIALI SPECIALI PERTECNOLOGIE AVANZATE SCRL IN BREVE ISRIM S.CONS. A R.L.

 Organization address address: LOCALITA PENTIMA BASSA 21
city: Terni
postcode: 5100

contact info
Titolo: Dr.
Nome: Daniela
Cognome: Rossi
Email: send email
Telefono: +39 0744 547801
Fax: +39 0744 470174

IT (Terni) participant 507˙788.30
4    CENTRO AGRICOLTURA E AMBIENTE GIORGIO NICOLI SRL

 Organization address address: VIA ARGINI NORD 3351
city: CREVALCORE
postcode: 40014

contact info
Titolo: Dr.
Nome: Romeo
Cognome: Bellini
Email: send email
Telefono: 39051873436
Fax: 390517000000

IT (CREVALCORE) participant 451˙149.87
5    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

 Organization address address: Rue Michel -Ange 3
city: PARIS
postcode: 75794

contact info
Titolo: Ms.
Nome: Christine
Cognome: Brunel
Email: send email
Telefono: 33388106050
Fax: 33388108615

FR (PARIS) participant 360˙237.99
6    INSTITUT PASTEUR

 Organization address address: RUE DU DOCTEUR ROUX 25-28
city: PARIS CEDEX 15
postcode: 75724

contact info
Titolo: Dr.
Nome: Marie-Laure
Cognome: Rosso
Email: send email
Telefono: +33 1 4438 9526
Fax: +33 1 4061 3940

FR (PARIS CEDEX 15) participant 301˙769.60
7    UNIVERSITY OF KEELE

 Organization address address: KEELE UNIVERSITY FINANCE DPT
city: KEELE
postcode: ST5 5BG

contact info
Titolo: Ms.
Nome: Ann M.
Cognome: Diskin
Email: send email
Telefono: +44 1782 734463
Fax: +44 1782 733740

UK (KEELE) participant 287˙942.50
8    EUROPEAN MOLECULAR BIOLOGY LABORATORY

 Organization address address: Meyerhofstrasse 1
city: HEIDELBERG
postcode: 69117

contact info
Titolo: Ms.
Nome: Barbara
Cognome: Baron
Email: send email
Telefono: 441223000000
Fax: 441223000000

DE (HEIDELBERG) participant 223˙377.00
9    UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA

 Organization address address: Piazzale Aldo Moro 5
city: ROMA
postcode: 185

contact info
Titolo: Dr.
Nome: Aldo
Cognome: Liccardi
Email: send email
Telefono: +39 06 49914992
Fax: +39 06 4991 4986

IT (ROMA) participant 184˙928.82
10    INSTITUTO DE HIGIENE E MEDICINA TROPICAL

 Organization address address: Rua da Junqueira 100
city: LISBOA
postcode: 1349-008

contact info
Titolo: Dr.
Nome: Carla Cristina
Cognome: Gonçalves Firmo Ribeiro Bras
Email: send email
Telefono: 351214000000
Fax: 351214000000

PT (LISBOA) participant 179˙900.00
11    Oxitec Limited

 Organization address address: Miton park 71
city: Oxford
postcode: OX14 4RX

contact info
Titolo: Ms.
Nome: Ann
Cognome: Kramer
Email: send email
Telefono: +44 1235 433545
Fax: +44 1235 861138

UK (Oxford) participant 178˙630.00
12    FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS

 Organization address address: N PLASTIRA STR 100
city: HERAKLION
postcode: 70013

contact info
Titolo: Ms.
Nome: Zizi
Cognome: Papatheodorou
Email: send email
Telefono: 302810000000
Fax: 302810000000

EL (HERAKLION) participant 152˙656.00
13    LIVERPOOL SCHOOL OF TROPICAL MEDICINE

 Organization address address: Pembroke Place
city: LIVERPOOL
postcode: L35QA

contact info
Titolo: Mr.
Nome: Einion
Cognome: Holland
Email: send email
Telefono: +44 151 7053167
Fax: +44 151 7053363

UK (LIVERPOOL) participant 150˙760.00
14    ISTITUTO SUPERIORE DI SANITA

 Organization address address: Viale Regina Elena 299
city: ROMA
postcode: 161

contact info
Titolo: Dr.
Nome: Rosa Maria
Cognome: Martoccia
Email: send email
Telefono: +39 06 49902688
Fax: +39 06 49903007

IT (ROMA) participant 142˙600.00
15    WAGENINGEN UNIVERSITY

 Organization address address: DROEVENDAALSESTEEG 4
city: WAGENINGEN
postcode: 6708 PB

contact info
Titolo: Prof.
Nome: Rudie
Cognome: Jullens
Email: send email
Telefono: +31 317 484652
Fax: +31 317 484821

NL (WAGENINGEN) participant 138˙000.00
16    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD

 Organization address address: University Offices, Wellington Square
city: OXFORD
postcode: OX1 2JD

contact info
Titolo: Ms.
Nome: Toni
Cognome: Wheeler
Email: send email
Telefono: +44 1865 281328
Fax: +44 1865 310447

UK (OXFORD) participant 135˙970.00
17    Nome Ente NON disponibile

 Organization address address: Rue du Centre Pasteur 2007
city: Yaounde

contact info
Titolo: Mr.
Nome: Fulgence
Cognome: Likassi-Bokamba
Email: send email
Telefono: +237 2223 2232
Fax: +237 2223 0061

CM (Yaounde) participant 124˙450.00
18    INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT

 Organization address address: Boulevard de Dunkerque - CS 90009 44
city: MARSEILLE
postcode: 13572

contact info
Titolo: Ms.
Nome: Ariel
Cognome: Crozon
Email: send email
Telefono: +33 491 999456
Fax: +33 491 999456

FR (MARSEILLE) participant 121˙370.00
19    International Centre of Insect Physiology and Ecology

 Organization address address: "Off Thika Road, Duduville Campus"
city: Nairobi
postcode: 100

contact info
Titolo: Prof.
Nome: Christian
Cognome: Borgemeister
Email: send email
Telefono: 254209000000
Fax: 254209000000

KE (Nairobi) participant 119˙995.00
20    MINISTERE DE LA SANTE

 Organization address city: 7003 Ouagadougou 03

contact info
Titolo: Mr.
Nome: Karim
Cognome: Ouedraogo
Email: send email
Telefono: 22650324695
Fax: 22650310477

BF (7003 Ouagadougou 03) participant 117˙619.00
21    CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE ET TECHNOLOGIQUE*INSTITUT DE RECHERCHE EN SCIENCES DE LA SANTE

 Organization address address: B P 7047
city: OUAGADOUGOU
postcode: 3

contact info
Titolo: Mr.
Nome: P. François
Cognome: Kiendrebeogo
Email: send email
Telefono: +226 20974868
Fax: +226 20974868

BF (OUAGADOUGOU) participant 110˙000.00
22    UNIVERSITA DEGLI STUDI DI PAVIA

 Organization address address: STRADA NUOVA 65
city: PAVIA
postcode: 27100

contact info
Titolo: Dr.
Nome: Sofia
Cognome: Baggini
Email: send email
Telefono: +39 0382 984227
Fax: +39 0382 986906

IT (PAVIA) participant 108˙270.00
23    AGRICULTURAL UNIVERSITY OF ATHENS

 Organization address address: Iera Odos 75
city: ATHENS
postcode: 11855

contact info
Titolo: Prof.
Nome: Eleftheria
Cognome: Panopoulou
Email: send email
Telefono: 302105000000

EL (ATHENS) participant 107˙642.40
24    INSTITUT PASTEUR DE DAKAR

 Organization address address: Avenue Pasteur 36
city: DAKAR
postcode: DAKAR

contact info
Titolo: Dr.
Nome: Philippe
Cognome: Mauclere
Email: send email
Telefono: +221 33 8399201
Fax: +221 33 8399210

SN (DAKAR) participant 100˙450.00
25    STICHTING KATHOLIEKE UNIVERSITEIT

 Organization address address: GEERT GROOTEPLEIN NOORD 9
city: NIJMEGEN
postcode: 6525 EZ

contact info
Titolo: Dr.
Nome: Annemieke
Cognome: Annemieke Jansens
Email: send email
Telefono: +31 24 3614357
Fax: +31 24 3540216

NL (NIJMEGEN) participant 98˙849.60
26    UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II.

 Organization address address: Corso Umberto I 40
city: NAPOLI
postcode: 80138

contact info
Titolo: Dr.
Nome: Federico
Cognome: Turano
Email: send email
Telefono: +39 081 679228
Fax: +39 081 679233

IT (NAPOLI) participant 95˙401.18
27    UNIVERSITY OF GLASGOW

 Organization address address: University Avenue
city: GLASGOW
postcode: G12 8QQ

contact info
Titolo: Mr.
Nome: Joe
Cognome: Galloway
Email: send email
Telefono: +44 141 3303884
Fax: +44 141 3303218

UK (GLASGOW) participant 95˙190.00
28    UNIVERSITAETSKLINIKUM HEIDELBERG

 Organization address address: IM NEUENHEIMER FELD 672
city: HEIDELBERG
postcode: 69120

contact info
Titolo: Mr.
Nome: Thorsten
Cognome: Brietz
Email: send email
Telefono: +49 6221 567086
Fax: +49 6221 565460

DE (HEIDELBERG) participant 93˙999.60
29    UNIVERSITA DEGLI STUDI DI CAMERINO

 Organization address address: PIAZZA CAVOUR 19F
city: CAMERINO
postcode: 62032

contact info
Titolo: Mr.
Nome: Ermanno
Cognome: Pieroni
Email: send email
Telefono: +39 0737 402171
Fax: +39 0737 402846

IT (CAMERINO) participant 86˙704.00
30    MED BIOTECH LABORATORIES

 Organization address address: "Lugwana Close, Myenga Tank Hill By-Pass"
city: KAMPALA
postcode: 256

contact info
Titolo: Dr.
Nome: Bernard
Cognome: Kanoi
Email: send email
Telefono: +256 782 334853
Fax: +256 41 510 408

UG (KAMPALA) participant 82˙740.00
31    STOCKHOLMS UNIVERSITET

 Organization address address: Universitetsvaegen 10
city: STOCKHOLM
postcode: 10691

contact info
Titolo: Ms.
Nome: Ulla
Cognome: Jungmarker
Email: send email
Telefono: +46 816 2257
Fax: +46 816 4315

SE (STOCKHOLM) participant 80˙000.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

disease    climate    genetically    malaria    anopheles    effort    capacity    mosquitos    vector    gambiae    struggling    release    diseases    capability    infravec    rearing    genetics    albopictus    vectors    aedes    facilities    populations    health    offers    viral    insecticide    threat    trade    modified    mainly    biology    posed    expertise    spread    facility    transgenic    spreading    infrastructure    ae    genes    mosquitoes    considerably    public    gm    genetic    made    confined    tourism    mosquito    international   

 Obiettivo del progetto (Objective)

Mosquitoes transmit a variety of infectious diseases that cause a tremendous burden to public health. Due to climate changes and to the increase in international trade and tourism the threats posed by mosquitoes are increasingly affecting large parts of Europe, causing understandable concerns among the populations of many Member States. Control methods, mainly based on insecticide usage, are struggling to cope with the challenges posed by the biology and ecology of mosquito vectors. INFRAVEC aims at bridging the gap between the recent advances in transgenic technology and its implementation as a novel powerful approach for vector control. To this aim, a large European Infrastructure will be established, in which the coordination of efforts, expertise and facilities provided by the individual research groups and institutions will bolster and considerably expand the overall research capabilities of the research community. INFRAVEC will operate, through a number of Networking, Joint Research, Transnational and Service activities, towards the objective of considerably strengthening research capability in Europe by sharing knowledge, resources and technology. INFRAVEC will mainly focus on Anopheles gambiae, the major vector of malaria, and Aedes albopictus, a viral disease vector that is rapidly spreading through Europe. Four Infrastructure facilities will be integrated in the project: 1) the Genetically Modified mosquito laboratory of Imperial College London; 2) the Mosquito Mass-rearing facility at the Centro Agricoltura ed Ambiente (with the support of the International Atomic Energy Agency); 3) the Bioinformatics facility at EMBLEBI, UK; and 4) the Mosquito Confined Release facility at ISRIM. INFRAVEC will provide a formidable research capability to external users and facilitate the performance of five research projects aimed at utilizing basic knowledge of mosquito genetics and biology in an unprecedented effort to develop novel opportunities for mosquito control.

Descrizione progetto (Article)

With climate change and increasing international trade and tourism, the threat of mosquito-carried disease is spreading. Conventional control methods employing insecticide use are struggling to meet the challenge.

The ability to target specific essential mosquito genes, and to introduce genes from one species into another using transgenic technology will possibly allow to control vector spread at genetic level. The EU-funded project 'Research capacity for the implementation of genetic control of mosquitoes' (INFRAVEC) is integrating mosquito genetics expertise with unique mosquito rearing and confined release infrastructures and offers researchers across Europe access to these cutting-edge research facilities. The consortium consists of 31 academic and industrial laboratories.

The multi-center facility offers to create and make available a comprehensive mosquito line repository facility for both genetically modified (GM) and field-derived mosquitoes. In addition, researchers acquired a custom-made, high-throughput, fully automated sorting instrument that allows to discriminate between genetically divergent mosquito larvae.

The two mosquito vectors provided for under this research infrastructure are Anopheles gambiae, the major vector of malaria, and Aedes albopictus, a vector carrying viral diseases that continues to spread. Genetic research resources for Ae. Albopictus are currently quite limited, but are being expanded under this project.

During this reporting period, a large effort was devoted to generating the required genetic databases. Investigators also made important progress towards understanding and genetically manipulating vectorial capacity, reproduction and immunity as routes to minimise their spread.

Researchers are also comparing the population structure of Ae. albopictus in its native habitat with those populations that have recently colonised Europe in order to identify genetic changes that may be associated with the spread of the new populations. Controlled release of GM mosquitoes is the ultimate goal. To that end, a small, 'semi-field' experimental set-up is currently being developed, a so-called confined release facility, that allows e.g. including studying the viability, competitiveness and safety of genetically modified mosquitos.

Mosquito-borne diseases are on the rise and spreading across the globe due to a combination of global climate change and increased trade and tourism. INFRAVEC brings together experts in mosquito biology, genetics, epidemiology, genetic engineering and more, to boost research to confront the spread of disease-carrying mosquitos that pose a great threat to public health.

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