ENPRA

RISK ASSESSMENT OF ENGINEERED NANOPARTICLES

 Coordinatore INSTITUTE OF OCCUPATIONAL MEDICINE 

 Organization address address: Research Avenue North, Riccarton 45
city: EDINBURGH
postcode: EH14 4AP

contact info
Titolo: Ms.
Nome: Susy
Cognome: Scarisbrick
Email: send email
Telefono: +44 131 449 8065
Fax: +44 131 449 8084

 Nazionalità Coordinatore United Kingdom [UK]
 Sito del progetto http://www.enpra.eu
 Totale costo 5˙269˙000 €
 EC contributo 3˙700˙000 €
 Programma FP7-NMP
Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies
 Code Call FP7-NMP-2008-SMALL-2
 Funding Scheme CP-FP
 Anno di inizio 2009
 Periodo (anno-mese-giorno) 2009-05-01   -   2012-10-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    INSTITUTE OF OCCUPATIONAL MEDICINE

 Organization address address: Research Avenue North, Riccarton 45
city: EDINBURGH
postcode: EH14 4AP

contact info
Titolo: Ms.
Nome: Susy
Cognome: Scarisbrick
Email: send email
Telefono: +44 131 449 8065
Fax: +44 131 449 8084

UK (EDINBURGH) coordinator 400˙680.00
2    RIJKSINSTITUUT VOOR VOLKSGEZONDHEIDEN MILIEU*NATIONAL INSTITUTEFOR PUBLIC HEALTH AND THE ENVIRONMENTEN

 Organization address address: Antonie Van Leeuwenhoeklaan 9
city: BILTHOVEN
postcode: 3721 MA

contact info
Titolo: Dr.
Nome: Thedo
Cognome: Blijdenstein
Email: send email
Telefono: +31 30 2743066
Fax: +31 30 2744452

NL (BILTHOVEN) participant 351˙402.00
3    HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH

 Organization address address: Ingolstaedter Landstrasse 1
city: MUENCHEN
postcode: 85764

contact info
Titolo: Dr.
Nome: Ertel
Cognome: Juergen
Email: send email
Telefono: +49 89 3187 3022
Fax: +49 89 3187 3866

DE (MUENCHEN) participant 290˙333.00
4    UNIVERSITA CA' FOSCARI VENEZIA

 Organization address address: DORSODURO 3246
city: VENEZIA
postcode: 30123

contact info
Titolo: Ms.
Nome: Stefania
Cognome: Quaderni
Email: send email
Telefono: +39 041 234 8548
Fax: +39 041 234 8940

IT (VENEZIA) participant 286˙025.00
5    JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION

 Organization address address: Rue de la Loi 200
city: BRUSSELS
postcode: 1049

contact info
Titolo: Mr.
Nome: Clemens
Cognome: Wittwehr
Email: send email
Telefono: +39 0332789828
Fax: +39 0332789828

BE (BRUSSELS) participant 281˙757.00
6    DET NATIONALE FORSKNINGSCENTER FORARBEJDSMILJO

 Organization address address: LERSO PARKALLE 105
city: KOBENHAVN
postcode: 2100

contact info
Titolo: Mr.
Nome: Arne Bjerre
Cognome: Harbo
Email: send email
Telefono: 4539155200
Fax: 4539165201

DK (KOBENHAVN) participant 271˙300.00
7    VRIJE UNIVERSITEIT BRUSSEL

 Organization address address: PLEINLAAN 2
city: BRUSSEL
postcode: 1050

contact info
Titolo: Ms.
Nome: Martina
Cognome: Follet
Email: send email
Telefono: 3226292210
Fax: 3226293640

BE (BRUSSEL) participant 260˙559.00
8    THE UNIVERSITY OF EDINBURGH

 Organization address address: OLD COLLEGE, SOUTH BRIDGE
city: EDINBURGH
postcode: EH8 9YL

contact info
Titolo: Ms.
Nome: Noble
Cognome: Angela
Email: send email
Telefono: 441317000000
Fax: 441317000000

UK (EDINBURGH) participant 217˙810.00
9    UNIVERSITE PARIS DIDEROT - PARIS 7

 Organization address address: RUE THOMAS MANN 5
city: PARIS
postcode: 75205

contact info
Titolo: Ms.
Nome: Muriel
Cognome: Maurice
Email: send email
Telefono: +33 157275548
Fax: +33 157275547

FR (PARIS) participant 200˙726.00
10    INSTITUT FUR UMWELTMEDIZINISCHE FORSCHUNG AN DER HEINRICH-HEINE-UNIVERSITAT DUSSELDORF GMBH

 Organization address address: AUF M HENNEKAMP 50
city: DUESSELDORF
postcode: 40225

contact info
Titolo: Mr.
Nome: Michael
Cognome: Hovelmann
Email: send email
Telefono: +49 211 3389 380
Fax: +49 211 3389 388

DE (DUESSELDORF) participant 194˙889.00
11    KATHOLIEKE UNIVERSITEIT LEUVEN

 Organization address address: Oude Markt 13
city: LEUVEN
postcode: 3000

contact info
Titolo: Ms.
Nome: Rabia
Cognome: Ozkan
Email: send email
Telefono: +32 16 329976
Fax: +32 16 326515

BE (LEUVEN) participant 194˙889.00
12 KOBENHAVNS UNIVERSITET DK participant 194˙889.00
13    UNIVERSITE CATHOLIQUE DE LOUVAIN

 Organization address address: Place De L'Universite 1
city: LOUVAIN LA NEUVE
postcode: 1348

contact info
Titolo: Ms.
Nome: Cecile
Cognome: Sibille
Email: send email
Telefono: 3210472833
Fax: 3210473803

BE (LOUVAIN LA NEUVE) participant 194˙889.00
14    COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

 Organization address address: RUE LEBLANC 25
city: PARIS 15
postcode: 75015

contact info
Titolo: Mr.
Nome: Xavier
Cognome: Lemoine
Email: send email
Telefono: +33 438782593
Fax: +33 438782626

FR (PARIS 15) participant 168˙298.00
15    HERIOT-WATT UNIVERSITY

 Organization address address: Riccarton
city: EDINBURGH
postcode: EH14 4AS

contact info
Titolo: Dr.
Nome: Eva
Cognome: Olszewska-Day
Email: send email
Telefono: +44 131 4513073
Fax: +44 131 4513193

UK (EDINBURGH) participant 153˙186.00
16    EDINBURGH NAPIER UNIVERSITY

 Organization address address: COLINTON ROAD 219
city: EDINBURGH
postcode: EH14 1DJ

contact info
Titolo: Ms.
Nome: Colette
Cognome: Pemberton
Email: send email
Telefono: +44 131 455 6009
Fax: +44 131 455 6552

UK (EDINBURGH) participant 38˙368.00
17    DUKE UNIVERSITY

 Organization address address: BLACKWELL ST SUITE 920 324
city: DURHAM
postcode: 27701

contact info
Titolo: Ms.
Nome: Mary
Cognome: Johnson
Email: send email
Telefono: +1919688 5851
Fax: +1 919 684 8377

US (DURHAM) participant 0.00
18    UNIVERSITY OF ROCHESTER

 Organization address address: "ELMWOOD AVENUE, BOX EHSC 601"
city: ROCHESTER NY
postcode: 14642

contact info
Titolo: Dr.
Nome: Jane
Cognome: Tolbert
Email: send email
Telefono: +1 585 275 4210
Fax: +1 585 275 9492

US (ROCHESTER NY) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

exposure    vii    universities    animal    vitro    us    enp    models    risk    scientists    vivo    nanotoxicology    health    validate   

 Obiettivo del progetto (Objective)

'Engineered Nanoparticles (ENP) are increasingly produced for use in a wide range of industrial and consumer products. Yet it is known that exposure to some types of particles can cause severe health effects. Therefore it is essential to ascertain whether exposure to ENP can lead to possible health risks for workers and consumers. We have formed a consortium of well-known scientists from European Universities and Research Institutes, with over 100 publications in the field of Nanotoxicology. Our aim is to develop an approach for the Risk Assessment of ENP (ENPRA). Our objectives are: (i) to obtain a bank of commercial ENP with contrasting physico-chemical characteristics and measure them; (ii) to investigate the toxic effects of ENP on 5 (pulmonary, hepatic, renal, cardiovascular and developmental) target systems and 5 endpoints (oxidative stress, inflammation; immuno-toxicity; fibrogenecity; genotoxicity) using in vitro animal/human models; (iii) to validate the in vitro findings with a small set of carefully chosen in vivo animal experiments; (iv) to construct mathematical models to extrapolate the exposure-dose-response relationship from in vitro to in vivo and to humans; (v) to use QSAR like models to identify the key ENP characteristics driving the adverse effects; (vi) to implement a risk assessment of ENP using the Weight-of-Evidence approach; (vii) to disseminate our findings to potential stakeholders. To harmonise the research activities between our EU group and the US, we have established links with scientists from US Universities (Duke, Rochester) and Government Agencies (NIH/NIEHS, NIOSH and EPA) with on-going research in Nanotoxicology. Our objectives here are (vii) to share information and agree on experimental protocols; (viii) to avoid duplication of work; (ix) to further validate the findings of this proposed study.'

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