MEM-S

Bottom-up design and fabrication of industrial bio-inorganic nano-porous membranes with novel functionalities based on principles of protein self-assembly and biomineralization

 Coordinatore UNIVERSITATSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAT MAINZ 

 Organization address address: Langenbeckstrasse 1
city: Mainz
postcode: 55131

contact info
Titolo: Prof.
Nome: Werner E.G.
Cognome: Müller
Email: send email
Telefono: +49 6131 3925910
Fax: +49 6131 3925243

 Nazionalità Coordinatore Germany [DE]
 Sito del progetto http://www.eu-mem-s.de
 Totale costo 3˙649˙407 €
 EC contributo 2˙816˙819 €
 Programma FP7-KBBE
Specific Programme "Cooperation": Food, Agriculture and Biotechnology
 Code Call FP7-KBBE-2009-3
 Funding Scheme CP-FP
 Anno di inizio 2010
 Periodo (anno-mese-giorno) 2010-01-01   -   2012-12-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    UNIVERSITATSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAT MAINZ

 Organization address address: Langenbeckstrasse 1
city: Mainz
postcode: 55131

contact info
Titolo: Prof.
Nome: Werner E.G.
Cognome: Müller
Email: send email
Telefono: +49 6131 3925910
Fax: +49 6131 3925243

DE (Mainz) coordinator 630˙634.00
2    UNIVERSITAET FUER BODENKULTUR WIEN

 Organization address address: Gregor Mendel Strasse 33
city: WIEN
postcode: 1180

contact info
Titolo: Prof.
Nome: Uwe B.
Cognome: Sleytr
Email: send email
Telefono: +43 1 47654 2201
Fax: +43 1 47891 12

AT (WIEN) participant 555˙180.00
3    WAGENINGEN UNIVERSITY

 Organization address address: DROEVENDAALSESTEEG 4
city: WAGENINGEN
postcode: 6708 PB

contact info
Titolo: Mr.
Nome: Jos
Cognome: Teunissen
Email: send email
Telefono: +31 317 485313
Fax: +31 317 484612

NL (WAGENINGEN) participant 309˙400.00
4    LIONIX BV

 Organization address address: HENGELOSESTRAAT 500
city: ENSCHEDE
postcode: 7521 AN

contact info
Titolo: Mr.
Nome: Henk
Cognome: Leeuwis
Email: send email
Telefono: +31 53 489 3827
Fax: +31 53 489 3601

NL (ENSCHEDE) participant 302˙685.00
5    AQUAMARIJN MICRO FILTRATION BV

 Organization address address: BERKELKADE 11
city: ZUTPHEN
postcode: 7201JE

contact info
Titolo: Prof.
Nome: Cees J.M.
Cognome: Van Rijn
Email: send email
Telefono: -520295
Fax: -8823257

NL (ZUTPHEN) participant 270˙600.00
6    IWW RHEINISCH WESTFALISCHES INSTITUT FUR WASSERFORSCHUNG GEMEINNUTZIGE GMBH

 Organization address address: MORITZSTRASSE 26
city: MULHEIM AN DER RUHR
postcode: 45476

contact info
Titolo: Mr.
Nome: Klaus-Dieter
Cognome: Neumann
Email: send email
Telefono: +49 208 40303 500
Fax: +49 208 40303 80

DE (MULHEIM AN DER RUHR) participant 252˙600.00
7    UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6

 Organization address address: Place Jussieu 4
city: PARIS
postcode: 75252

contact info
Titolo: Dr.
Nome: Elena
Cognome: Billi-Rizza
Email: send email
Telefono: +33 1 44275517
Fax: +33 1 44274769

FR (PARIS) participant 250˙000.00
8    NanotecMARIN GmbH

 Organization address address: Duesbergweg 6
city: Mainz
postcode: D 55099

contact info
Titolo: Ms.
Nome: Jasmine
Cognome: Grams
Email: send email
Telefono: +49 6966 127713
Fax: +49 6966 127712

DE (Mainz) participant 245˙720.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

industrial    food    functionalized    technologies    drug    biology    enzymes    silica    layer    sensors    functionalities    membranes    bio    biomolecules    nano    discovery    protein    porous    silicatein    technique    proteins    formed    molecular    inorganic   

 Obiettivo del progetto (Objective)

'There is strong interest in the development of novel functionalized membranes which can be used as microsieves, as a component of integrated analytical systems, in food processing, drug discovery and diagnostic applications. This project is based on a combination of three break-through technologies, developed by the applicants in the past, with high impact for nano(bio)technological application: (i) the S-layer technology allowing the construction of nanoporous protein lattices, (ii) the biocatalytic formation of inorganic materials by silicatein, a group of unique enzymes capable to catalyze the formation of porous silica from soluble precursors, and (iii) the sol-gel technique for encapsulation (immobilization) of biomolecules serving as biocatalyst or as a component of sensors. The goal of this project is to design and fabricate - based on molecular biology inspired approaches - nano-porous bio-inorganic membranes with novel functionalities for industrial application. These membranes will be formed by S-layer proteins, which are able to assemble to highly ordered structures of defined pore-size, and recombinant silicateins or silicatein fusion proteins. The hydrated silica glass layer formed by silicatein will be used to encase biocatalysts (enzymes) or antibodies against small molecules as sample prep- or sensor components of integrated systems. The innovative type of the functionalized membranes developed in this project thus exploits two principles: (i) protein self-assembly and - and this has not been done before - (ii) enzymatic (silicatein-mediated) deposition of inorganic material used for reinforcement of the membranes as well as for encasing biomolecules, providing the membranes with new functionalities. The new technique will be exploited by three research-based SMEs and the enduser involved in the project, in microfluidics based sample processing and micro-array development, in industrial nanosieves, as well as in sensors in drinking water systems.'

Introduzione (Teaser)

Combining nanotechnology with molecular biology has enabled the development of several breakthrough technologies for wide-ranging industrial applications in food processing, drug discovery and diagnosis. For the first time ever, EU-funded scientists developed bio-functionalised protein membranes for an extensive host of industrial applications.

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PHARMASEA (2012)

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POLYMODE (2009)

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