HICONTCELLSCREEN

Development of systems for high content screening of live cells

Coordinatore	TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY    more  Organization address address: TECHNION CITY - SENATE BUILDING city: HAIFA postcode: 32000 contact info Titolo: Mr. Nome: Mark Cognome: Davison Email: send email Telefono: -8293886 Fax: -8231990
Nazionalità Coordinatore	Israel [IL]
Totale costo	50˙000 €
EC contributo	50˙000 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2009-RG
Funding Scheme	MC-IRG
Anno di inizio	0
Periodo (anno-mese-giorno)	0000-00-00   -   0000-00-00

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY  Organization address address: TECHNION CITY - SENATE BUILDING city: HAIFA postcode: 32000 contact info Titolo: Mr. Nome: Mark Cognome: Davison Email: send email Telefono: -8293886 Fax: -8231990	IL (HAIFA)	coordinator	50˙000.00

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 Obiettivo del progetto (Objective)

'Light microscopy has many applications in the life and health sciences. These applications include drug screening, in vitro fertilization, medical diagnostics and basic research in cell and systems biology [ref]. Many of these applications require the imaging of multiple samples over extended periods of times using a methodology that is often referred to as High Content Screening (HCS). Systems for performing HCS do exist, however thes systems generally provide a solution for a limited range of problems. Consequently there are many systems for which no suitable HCS technology is available. The first system involves a culture of primary naïve T-cells in conjunction with antigen presenting dendritic cells (APCs), which is used for studying the biology of T-cell activation. The second system involves nvolves the culture of primary rat neurons transfected to express fluorescently labelled synapse markers on Multi-Electrode Arrays (MEAs) dishes. This system is being used to study the connection between neural network structure and the electric activity of the network. We propose to develop novel software and hardware technology that will enable efficient research using these systems.'