TIMET

Linking the clock to metabolism

 Coordinatore THE UNIVERSITY OF EDINBURGH 

 Organization address address: OLD COLLEGE, SOUTH BRIDGE
city: EDINBURGH
postcode: EH8 9YL

contact info
Titolo: Ms.
Nome: Angela
Cognome: Noble
Email: send email
Telefono: +44 131 650 9024
Fax: +44 131 650 9023

 Nazionalità Coordinatore United Kingdom [UK]
 Totale costo 7˙652˙635 €
 EC contributo 5˙844˙329 €
 Programma FP7-KBBE
Specific Programme "Cooperation": Food, Agriculture and Biotechnology
 Code Call FP7-KBBE-2009-3
 Funding Scheme CP-IP
 Anno di inizio 2010
 Periodo (anno-mese-giorno) 2010-03-01   -   2015-02-28

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF EDINBURGH

 Organization address address: OLD COLLEGE, SOUTH BRIDGE
city: EDINBURGH
postcode: EH8 9YL

contact info
Titolo: Ms.
Nome: Angela
Cognome: Noble
Email: send email
Telefono: +44 131 650 9024
Fax: +44 131 650 9023

UK (EDINBURGH) coordinator 1˙039˙394.00
2    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZURICH

 Organization address address: Raemistrasse 101
city: ZUERICH
postcode: 8092

contact info
Titolo: Dr.
Nome: Wilhelm
Cognome: Gruissem
Email: send email
Telefono: +41 44 632 0857
Fax: +41 44 632 1079

CH (ZUERICH) participant 1˙639˙208.00
3    MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.

 Organization address address: Hofgartenstrasse 8
city: MUENCHEN
postcode: 80539

contact info
Titolo: Mr.
Nome: Lothar
Cognome: Grube
Email: send email
Telefono: +49 331 567 8400
Fax: +49 331 567 8408

DE (MUENCHEN) participant 1˙459˙000.00
4    JOHN INNES CENTRE

 Organization address address: "Norwich Research Park, Colney"
city: NORWICH
postcode: NR4 7UH

contact info
Titolo: Dr.
Nome: Mary
Cognome: Anderson
Email: send email
Telefono: +44 1603 450244
Fax: +44 1603 450045

UK (NORWICH) participant 599˙000.00
5    Nome Ente NON disponibile

 Organization address address: Jordi Girona 18
city: BARCELONA
postcode: 8034

contact info
Titolo: Ms.
Nome: Lali
Cognome: Sanz
Email: send email
Telefono: +34 934 006 146
Fax: +34 932 045 904

ES (BARCELONA) participant 508˙250.00
6    THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN

 Organization address address: KING'S COLLEGE REGENT WALK
city: ABERDEEN
postcode: AB24 3FX

contact info
Titolo: Dr.
Nome: Elizabeth
Cognome: Rattray
Email: send email
Telefono: +44 1224 274369
Fax: +44 1224 272319

UK (ABERDEEN) participant 303˙647.00
7    UNIVERSITY OF GLASGOW

 Organization address address: University Avenue
city: GLASGOW
postcode: G12 8QQ

contact info
Titolo: Mr.
Nome: Joe
Cognome: Galloway
Email: send email
Telefono: +44 141 330 3884

UK (GLASGOW) participant 287˙512.20
8    THE SCOTTISH CROP RESEARCH INSTITUTE

 Organization address address: "ERROL ROAD, INVERGOWRIE"
city: DUNDEE
postcode: DD2 5DA

contact info
Titolo: Dr.
Nome: Neil
Cognome: Hattersley
Email: send email
Telefono: +44 1382 562 731
Fax: +44 1382 568 503

UK (DUNDEE) participant 4˙739.98
9    THE JAMES HUTTON INSTITUTE

 Organization address address: ERROL ROAD INVERGOWRIE
city: DUNDEE
postcode: DD2 5DA

contact info
Titolo: Mrs.
Nome: Karen
Cognome: Robb
Email: send email
Telefono: +44 1382 56 8769
Fax: +44 844 928 5429

UK (DUNDEE) participant 3˙577.82

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

rate    models    starvation    plants    reserves    degradation    transcriptional    function    biology    post    starch    day    synthesis    productivity    translational    clock    night    emergent    metabolic    gene    metabolism    data    plant   

 Obiettivo del progetto (Objective)

'Optimal plant growth requires the orchestration of carbon metabolism over the day-night cycle, to avoid periods of starvation at night. Metabolism and growth at night are fueled by carbohydrates released by degradation of starch, synthesised from photosynthesis in the preceding day. Starch synthesis and degradation are regulated such that starch reserves are almost but not quite exhausted at the end of the night, in both long and short nights. We have recently found that this robust regulation is a function of the circadian clock, an endogenous timer that allows plants to anticipate and prepare for daily changes in their environment, and a paradigm for Systems Biology. The clock controls the rate of starch degradation at night, so that reserves last until the anticipated dawn. Starvation and growth arrest are avoided. This important discovery opens the way to new levels of understanding of the control of plant growth and productivity. TiMet assembles world leaders in experimental and theoretical plant Systems Biology to understand the regulatory interactions between the clock gene circuit and metabolism, and their emergent effects on growth and productivity. In addition to starch metabolism, we will study isoprenoid synthesis, an essential metabolic process linking starch metabolism to growth and development. Jointly-conducted experiments will use responses to day-length and light-quality regimes that perturb clock function, and a large set of mutants deficient in clock or central metabolic functions. High throughput technologies will enable study of transcriptional, post-transcriptional, translational and post-translational events, providing a depth of analysis hitherto unattained for either the clock or metabolism in plants. Innovative data mining and modelling platforms will underpin new, mechanistic models of each subsystem, will integrate them for the first time, and test the emergent effects of this dynamic system on plant growth rate and productivity.'

Introduzione (Teaser)

Researchers have collated a wide array of data on plant metabolism and the biological rhythms that govern this process. Using this data, they have built new and updated models of gene expression in plants.

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