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EuroMix SIGNED

EuroMix

Total Cost €

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EC-Contrib. €

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Partnership

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Project "EuroMix" data sheet

The following table provides information about the project.

Coordinator
RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU 

Organization address
address: Antonie Van Leeuwenhoeklaan 9
city: BILTHOVEN
postcode: 3721 MA
website: www.rivm.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Project website https://www.euromixproject.eu
 Total cost 8˙821˙295 €
 EC max contribution 7˙999˙097 € (91%)
 Programme 1. H2020-EU.3.2. (SOCIETAL CHALLENGES - Food security, sustainable agriculture and forestry, marine, maritime and inland water research, and the bioeconomy)
 Code Call H2020-SFS-2014-2
 Funding Scheme RIA
 Starting year 2015
 Duration (year-month-day) from 2015-05-15   to  2019-05-14

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU NL (BILTHOVEN) coordinator 1˙024˙699.00
2    STICHTING WAGENINGEN RESEARCH NL (WAGENINGEN) participant 1˙186˙874.00
3    BUNDESINSTITUT FUER RISIKOBEWERTUNG DE (BERLIN) participant 797˙875.00
4    UNIVERSITA DEGLI STUDI DI MILANO IT (MILANO) participant 592˙538.00
5    FOLKEHELSEINSTITUTTET NO (OSLO) participant 497˙738.00
6    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 484˙702.00
7    AGENCE NATIONALE DE LA SECURITE SANITAIRE DE L ALIMENTATION DE L ENVIRONNEMENT ET DU TRAVAIL FR (MAISONS ALFORT) participant 449˙286.00
8    UNIVERSITAT ROVIRA I VIRGILI ES (TARRAGONA) participant 425˙720.00
9    FERA SCIENCE LIMITED UK (LONDON) participant 371˙039.00
10    UNIVERSITEIT GENT BE (GENT) participant 348˙958.00
11    INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT FR (PARIS CEDEX 07) participant 348˙341.00
12    MATIS OHF IS (REYKJAVIK) participant 313˙681.00
13    INSTITUT NATIONAL DE L ENVIRONNEMENT ET DES RISQUES INERIS FR (VERNEUIL EN HALATTE) participant 298˙144.00
14    IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE UK (LONDON) participant 297˙500.00
15    BENAKI PHYTOPATHOLOGICAL INSTITUTE EL (ATHINA) participant 249˙633.00
16    STATNI ZDRAVOTNI USTAV CZ (PRAHA 10) participant 75˙093.00
17    DANMARKS TEKNISKE UNIVERSITET DK (KGS LYNGBY) participant 74˙982.00
18    NACIONALNI INSTITUT ZA JAVNO ZDRAVJE SI (LJUBLJANA) participant 50˙313.00
19    Ministry of Health of the Republic of Cyprus CY (Nicosia) participant 50˙000.00
20    EUROPEAN FRESH PRODUCE ASSOCIATION AISBL BE (BRUXELLES) participant 48˙750.00
21    HEALTH AND SAFETY EXECUTIVE UK (BOOTLE MERSEYSIDE) participant 13˙229.00
22    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH CH (ZUERICH) participant 0.00
23    THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS UK (LONDON) participant 0.00

Map

 Project objective

Euromix aim to develop an experimentally verified, tiered strategy for the risk assessment of mixtures of multiple chemicals derived from multiple sources across different life stages. The project takes account of the gender dimension and balances the risk of chemicals present in foods against the benefits of those foods. Important concepts for this new strategy are prioritisation criteria for chemicals based on their exposure and hazard characteristics and evaluation of the role of mode of action in grouping chemicals into cumulative assessment groups. In-silico and in-vitro tools will be developed and verified against in-vivo experiments, with focus on four selected endpoints (liver, hormones, development and immunology) to provide a full proof-of-principle. The EuroMix project will result in an innovative platform of bioassays for mixture testing and refined categorisation of chemicals in cumulative assessment groups. New hazard and exposure models will be embedded in a model toolbox, made available for stakeholders through an openly accessible web-based platform. Access to the web-based tools will be facilitated by training. Criteria will be set and guidance will be written on how to use and implement the tiered test strategy. Dissemination and harmonisation of the approach within EU, Codex Alimentarius, and WHO will be achieved by involving a.o. WHO and US-EPA in the project and by the participation of experts playing a key role in helping establish international food safety policies. It is expected that the new mechanism-based strategy, the bioassay platform, the openly accessible web-based model toolbox, and clear guidance on a tiered hazard and exposure test and risk assessment strategy will boost innovation in the public and private sector, provide a sound scientific basis for managing risks to public health from chemical mixtures, ultimately reduce the use of laboratory animals, and support the global discussion of risk assessment policies for mixtures.

 Deliverables

List of deliverables.
Specific recommendations regarding implementation of a mechanism-based test strategy for liver, developmental and endocrine for OECD Documents, reports 2020-04-22 09:35:07
Report on the comparative outcome of using new mechanism-based testing and consequences for animal testing and uncertainties in risk assessment Documents, reports 2020-04-22 09:35:07
Report of WHO consultation workshop and feasibility study Documents, reports 2020-04-22 09:35:07
Minutes of meetings with External Advisory Board Documents, reports 2020-04-22 09:35:07
Scientific paper ready for submission describing the PB-PK/D model approach Documents, reports 2020-04-22 09:35:07
Scientific article ready for publication describing the method to identify mixtures Documents, reports 2020-04-22 09:35:06
Report with recommendation for OECD and other international organisations Documents, reports 2020-04-22 09:35:07
Scientific article describing the PB-PK model for combined exposures Documents, reports 2020-04-22 09:35:06
Scientific paper ready for submission describing biomarker study Documents, reports 2020-04-22 09:35:07
Final version of EuroMix model toolbox including hazard and PB-PK/D models Other 2020-04-22 09:35:07
PB-PK/D modelling for the index compound of the chosen endpoints Other 2020-04-22 09:35:06
Minutes of meetings with Scientific Advisory Board Documents, reports 2020-04-22 09:35:07
Scientific article ready for submission describing the results of the in vitro testing of mixtures Documents, reports 2020-04-22 09:35:07
Report on stakeholder workshop 1 Documents, reports 2020-04-22 09:35:07
Report describing the methodology and results of the refine and retain approach Documents, reports 2020-04-22 09:35:07
Demonstration tool cumulative exposure assessment Demonstrators, pilots, prototypes 2020-04-22 09:35:06
Scientific paper ready for submission on models and software for QIVIVE and AOP Documents, reports 2020-04-22 09:35:07
Scientific article ready for submission describing the in vitro testing strategy for immune toxicity Documents, reports 2020-04-22 09:35:06
Validation of the aggregated model and comparison with USA software Documents, reports 2020-04-22 09:35:07
Scientific article ready for submission describing the case study for aggregated exposure assessment Documents, reports 2020-04-22 09:35:06
Report on stakeholder workshop 2 Documents, reports 2020-04-22 09:35:07
Guidance on the use of the new strategy for tiered testing and assessment Documents, reports 2020-04-22 09:35:07
Plan for the dissemination and exploitation of the results from EuroMix Documents, reports 2020-04-22 09:35:07
Scientific article ready for publication balancing risk of mixtures against benefits Documents, reports 2020-04-22 09:35:07
Proceedings and training material from first training session for stakeholders Demonstrators, pilots, prototypes 2020-04-22 09:35:07
Scientific article ready for publication describing the in vivo studies Documents, reports 2020-04-22 09:35:06
Scientific paper ready for submission on the EuroMix toolbox and software Documents, reports 2020-04-22 09:35:07
The use of QSAR and TTC approaches to prioritise chemicals for mixtures Documents, reports 2020-04-22 09:35:07
Scientific article ready for submission describing the in vitro testing strategy for developmental/endocrine toxicity Documents, reports 2020-04-22 09:35:07
Minutes of meetings discussing harmonisation between Europe, EPA and WHO Documents, reports 2020-04-22 09:35:07
Proceedings and training material from second training session for stakeholders Demonstrators, pilots, prototypes 2020-04-22 09:35:07
Scientific article rady for submission on cumulative assessment of mixtures of several chemical classes Documents, reports 2020-04-22 09:35:07
Report on the needs and attitudes of stakeholders to the test strategy Documents, reports 2020-04-22 09:35:07
Position paper on gaps to be filled in existing legislation Documents, reports 2020-04-22 09:35:04
Demonstration prototype of EuroMix model toolbox (module priority setting). Demonstrators, pilots, prototypes 2020-04-22 09:35:04
Informative posters and booklets/brochures Websites, patent fillings, videos etc. 2020-04-22 09:35:04
CAG-specific PCR arrays Other 2020-04-22 09:35:04
Pan for managing and releasing open data Open Research Data Pilot 2020-04-22 09:35:04
Report usefulness of the TTC concept for risk assessment of mixtures Documents, reports 2020-04-22 09:35:04
Gender Plan Documents, reports 2020-04-22 09:35:04
Report describing cumulative assessment groups for a broad range of chemicals, based on information extracted from (literature) databases Documents, reports 2020-04-22 09:35:04
Report on the use of in-silico methods for the prioritisation of mixtures thereof Documents, reports 2020-04-22 09:35:04
Website for EuroMix project Websites, patent fillings, videos etc. 2020-04-22 09:35:04
Scientific article ready for submission describing the in vitro testing strategy for liver toxicity Documents, reports 2020-04-22 09:35:04

Take a look to the deliverables list in detail:  detailed list of EuroMix deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Marc C. Kennedy, David G. Garthwaite, Waldo J. de Boer, Johannes W. Kruisselbrink
Modelling aggregate exposure to pesticides from dietary and crop spray sources in UK residents
published pages: 9892-9907, ISSN: 0944-1344, DOI: 10.1007/s11356-019-04440-7
Environmental Science and Pollution Research 26/10 2020-04-22
2018 Charles Laroche, Manoj Aggarwal, Hans Bender, Paul Benndorf, Barbara Birk, Jonathan Crozier, Gianni Dal Negro, Federica De Gaetano, Christian Desaintes, Iain Gardner, Bruno Hubesch, Amaia Irizar, David John, Vikas Kumar, Alfonso Lostia, Irene Manou, Mario Monshouwer, Boris P. Müller, Alicia Paini, Kirsty Reid, Timothy Rowan, Magdalini Sachana, Katrin Schutte, Catrina Stirling, Rob Taalman, Leon v
Finding synergies for 3Rs – Toxicokinetics and read-across: Report from an EPAA partners\' Forum
published pages: 5-21, ISSN: 0273-2300, DOI: 10.1016/j.yrtph.2018.08.006
Regulatory Toxicology and Pharmacology 99 2020-04-22
2016 van der Voet, H; de Boer, W; Kruisselbrink, J; van Lenthe, M; Crépet, A; Kennedy, M; Sprong, C; van Klaveren, J
Deliverable 6.1 - Demonstration prototype of the EuroMix model toolbox
published pages: , ISSN: , DOI: 10.5281/zenodo.1066087
1 2020-04-22
2016 van Klaveren, J; Sprong, C; Jongenelen, J; Husøy, T; Dirven, H; Peijnenburg, A
Deliverable 1.2 - Data management plan
published pages: , ISSN: , DOI: 10.5281/zenodo.1064629
1 2020-04-22
2016 Gunnlaugsdóttir, H; Jensen, S; Gylfadóttir, K; van Klaveren, J; Sporing, C; Hart, A; Nadal, M; Torrente, M; Garcia, T
Deliverable 10.2 - Informative poster and booklet/brochure
published pages: , ISSN: , DOI: 10.5281/zenodo.1066863
1 2020-04-22
2016 Rotter, S; Beronius, A; Hanberg, A; Zilliacus, J; Nikolopoulou, D; Machera, K; Solecki, R
Deliverable 9.1 - Report on mixtures and implementation strategy in Europe – Assessment of chemical mixtures under consideration of current and future regulatory requirements and scientific approaches
published pages: , ISSN: , DOI: 10.5281/zenodo.1067585
1 2020-04-22
2016 Kyriakopoulou, K; Nikolopoulou, D; Machera, K; Peijnenburg, A; Louca‐ Christodoulou, D; Hadjiloizou, P; Beronius, A; Håkansson, H; Hanberg, A; Eberini, I; Rorije, E
Deliverable 2.1 - Report describing cumulative assessment groups for a broad range of chemicals, based on information extracted from (literature) databases
published pages: , ISSN: , DOI: 10.5281/zenodo.1065327
1 2020-04-22
2016 van Klaveren, J; Sprong, C
Deliverable 1.1 – Gender Plan
published pages: , ISSN: , DOI: 10.5281/zenodo.1064620
1 2020-04-22
2018 Kennedy, Marc; Hart, Andrew; Roelofs, Victoria; Roelofs, Willem
Elicitation Tool 3
published pages: , ISSN: , DOI: 10.5281/zenodo.1243619
2020-04-22
2018 Elena Menegola, Francesca Metruccio, Maria Battistoni, Francesca Di Renzo, Angelo Moretto
Concentration-response analysis of data obtained in mouse foetuses exposed in utero at E8 to azole antifungals (cyproconazole and triadimefon) alone or in mixture
published pages: 21, ISSN: 0890-6238, DOI: 10.1016/j.reprotox.2018.06.080
Reproductive Toxicology 80 2020-04-22
2016 Gunnlaugsdóttir, H; Jensen, S; van Klaveren, J; Zilliacus, J; Durinck, S
Deliverable 10.3 - Plan for the dissemination and exploitation of the results from EuroMix
published pages: , ISSN: , DOI: 10.5281/zenodo.1066887
1 2020-04-22
2017 Sharon Compeer
Effects of chemical mixtures on the development of the head skeleton of zebrafish embryos and on sexual development of the zebrafish
published pages: , ISSN: , DOI:
2020-04-22
2016 Remco van der Kris
Skeletal malformations in zebrafish embryos to assess mixture effects
published pages: , ISSN: , DOI:
2020-04-22
2017 Ananditya Nugraha
Analysis of Head Skeletal Malformation in Zebrafish Embryos for Chemical Mixture Assessment: phenotype and Mode of Action
published pages: , ISSN: , DOI:
2020-04-22
2018 N. González, E. Schreiber, M. Torrente, V. Kumar, J.L. Domingo, M.M. Gómez
Assessment of reproductive toxicity of male rats through maternal exposure to dienestrol
published pages: S133, ISSN: 0378-4274, DOI: 10.1016/j.toxlet.2018.06.701
Toxicology Letters 295 2020-04-22
2018 S. Rotter, A. Beronius, A. R. Boobis, A. Hanberg, J. van Klaveren, M. Luijten, K. Machera, D. Nikolopoulou, H. van der Voet, J. Zilliacus, R. Solecki
Overview on legislation and scientific approaches for risk assessment of combined exposure to multiple chemicals: the potential EuroMix contribution
published pages: 796-814, ISSN: 1040-8444, DOI: 10.1080/10408444.2018.1541964
Critical Reviews in Toxicology 48/9 2020-04-22
2019 Francesca Di Renzo, Francesca Metruccio, Maria Battistoni, Angelo Moretto, Elena Menegola
Relative potency ranking of azoles altering craniofacial morphogenesis in rats: An in vitro data modelling approach
published pages: 553-560, ISSN: 0278-6915, DOI: 10.1016/j.fct.2018.12.004
Food and Chemical Toxicology 123 2020-04-22
2018 Claudia Luckert, Albert Braeuning, Georges de Sousa, Sigrid Durinck, Efrosini S. Katsanou, Parthena Konstantinidou, Kyriaki Machera, Emanuela S. Milani, Ad A. C. M. Peijnenburg, Roger Rahmani, Andreja Rajkovic, Deborah Rijkers, Anastasia Spyropoulou, Marianna Stamou, Geert Stoopen, Shana Sturla, Bernd Wollscheid, Nathalie Zucchini-Pascal, Alfonso Lampen
Adverse Outcome Pathway-Driven Analysis of Liver Steatosis in Vitro : A Case Study with Cyproconazole
published pages: 784-798, ISSN: 0893-228X, DOI: 10.1021/acs.chemrestox.8b00112
Chemical Research in Toxicology 31/8 2020-04-22
2019 Amélie Crépet, Marie Vanacker, Corinne Sprong, Waldo de Boer, Urska Blaznik, Marc Kennedy, Chris Anagnostopoulos, Despo Louca Christodoulou, Jiří Ruprich, Irena Rehurkova, José Luis Domingo, Bodil Hamborg Jensen, Francesca Metruccio, Angelo Moretto, Liesbeth Jacxsens, Pieter Spanoghe, David Senaeve, Hilko van der Voet, Jacob van Klaveren
Selecting mixtures on the basis of dietary exposure and hazard data: application to pesticide exposure in the European population in relation to steatosis
published pages: 291-306, ISSN: 1438-4639, DOI: 10.1016/j.ijheh.2018.12.002
International Journal of Hygiene and Environmental Health 222/2 2020-04-22
2016 Jeroen Meijer
A method to evaluate skeletal malformations in zebrafish embryos (in view of mixture toxicity assessment)
published pages: , ISSN: , DOI:
2020-04-22
2019 Maria Battistoni, Francesca Di Renzo, Elena Menegola, Frederic Yves Bois
Quantitative AOP based teratogenicity prediction for mixtures of azole fungicides
published pages: 72-81, ISSN: 2468-1113, DOI: 10.1016/j.comtox.2019.03.004
Computational Toxicology 11 2020-04-22
2018 M. Battistoni, F. Di Renzo, F. Metruccio, A. Moretto, E. Menegola
Relative potency ranking of azoles altering cranio-facial morphogenesis in rat: an in vitro data modelling approach
published pages: S193, ISSN: 0378-4274, DOI: 10.1016/j.toxlet.2018.06.868
Toxicology Letters 295 2020-04-22
2018 R.P. Sharma, M. Schuhmacher, V. Kumar
PBPK/PD coupled HPG SB model to analyze the reproductive toxicity of EDs: Case study on mixture effects of DEHP and TCDD
published pages: S249, ISSN: 0378-4274, DOI: 10.1016/j.toxlet.2018.06.1023
Toxicology Letters 295 2020-04-22
2016 Anke Boersma
The effect of mixtures on the development of the zebrafish
published pages: , ISSN: , DOI:
2020-04-22
2018 Raju Prasad Sharma, Marta Schuhmacher, Vikas Kumar
Development of a human physiologically based pharmacokinetic (PBPK) model for phthalate (DEHP) and its metabolites: A bottom up modeling approach
published pages: 152-162, ISSN: 0378-4274, DOI: 10.1016/j.toxlet.2018.06.1217
Toxicology Letters 296 2020-04-22
2018 Jan-Jaap Sirks
Mode of action definition in the context of mixture effects on skeletal development in zebrafish embryos
published pages: , ISSN: , DOI:
2020-04-22
2015 Gunnlaugsdóttir, H; Jensen, S
Deliverable 10.1 – Website for EuroMix project
published pages: , ISSN: , DOI: 10.5281/zenodo.1066786
1 2020-04-22
2019 Paul van Ommeren
Application of the dose addition model in complex mixture risk assessment
published pages: , ISSN: , DOI:
2020-04-22
2019 Carina Sujan
Gene expression patterns in zebrafish as an endpoint for the development of craniofacial aberrations caused by (environmental) pollutants
published pages: , ISSN: , DOI:
2020-04-22
2018 Vivianne Veenma
Analysis of the Mode of Action of chemicals inducing head skeletal malformations in zebrafish embryos
published pages: , ISSN: , DOI:
2020-04-22
2019 Karrer, Cecile
Consumer Exposure to Bisphenolic Compounds: Advancing Exposure and Pharmacokinetic Modeling
published pages: , ISSN: , DOI: 10.3929/ethz-b-000336637
2020-04-22
2019 Karrer, Cecile; von Goetz, Natalie; Hungerbühler, Konrad; Bokkers, Bas; Delmaar, Christiaan
PACEM. Shiny beta version 0.9.
published pages: , ISSN: , DOI:
2020-04-22
2018 Yvonne C. M. Staal, Jeroen Meijer, Remco J. C. van der Kris, Annamaria C. de Bruijn, Anke Y. Boersma, Eric R. Gremmer, Edwin P. Zwart, Piet K. Beekhof, Wout Slob, Leo T. M. van der Ven
Head skeleton malformations in zebrafish (Danio rerio) to assess adverse effects of mixtures of compounds
published pages: 3549-3564, ISSN: 0340-5761, DOI: 10.1007/s00204-018-2320-y
Archives of Toxicology 92/12 2020-04-22
2017 Raju Prasad Sharma, Marta Schuhmacher, Vikas Kumar
Developing integrated PBPK/PD coupled mechanistic pathway model (miRNA-BDNF): An approach towards system toxicology
published pages: 79-91, ISSN: 0378-4274, DOI: 10.1016/j.toxlet.2017.08.003
Toxicology Letters 280 2020-04-22
2018 Monica Andreassen, Hege Hjertholm, Hubert Dirven and Trine Husøy
Real-Life Exposure to Mixtures of Chemicals in the Euromix Human Biomonitoring Study: Results from Repeated 24-Hour Diaries Reporting the Use of Personal Care Products
published pages: Society of Toxic, ISSN: , DOI:
Toxicologist Database Toxicologist Database 2020-04-22
2016 Thomas Roiss
PBPK Modelling of BPA & BPF
published pages: , ISSN: , DOI:
2020-04-22
2016 Nicole Cramer
Physiologically based pharmacokinetic modelling of Bisphenol A in humans
published pages: , ISSN: , DOI:
2020-04-22
2016 Sharma, R. P., Schuhmacher. M. Kumar V.,
Developing PBPK/PD model to characterize the mixture effect of TCDD and DEHP altering estradiol kinetic in ovary via crosstalk mechanism
published pages: , ISSN: , DOI:
2020-04-22
2018 Charles Laroche, Manoj Aggarwal, Hans Bender, Paul Benndorf, Barbara Birk, Jonathan Crozier, Gianni Dal Negro, Federica De Gaetano, Christian Desaintes, Iain Gardner, Bruno Hubesch, Amaia Irizar, David John, Vikas Kumar, Alfonso Lostia, Irene Manou, Mario Monshouwer, Boris P. Müller, Alicia Paini, Kirsty Reid, Timothy Rowan, Magdalini Sachana, Katrin Schutte, Catrina Stirling, Rob Taalman, Leon van Aerts, Renate Weissenhorn, Ursula G. Sauer
Finding synergies for 3Rs – Toxicokinetics and read-across: Report from an EPAA partners\' Forum
published pages: 5-21, ISSN: 0273-2300, DOI: 10.1016/j.yrtph.2018.08.006
Regulatory Toxicology and Pharmacology 99 2020-04-22
2018 Monica Andreassen, Cecile Karrer, Natalie von Goetz, Amrit K. Sakhi, Hubert Dirven and Trine Husøy
S01.04.07. Verification of Aggregated Exposure to Bisphenols from Diet and Cosmetics - The Human Biomonitoring Study from the EU Project Euromix
published pages: , ISSN: , DOI:
2020-04-22
2016 Yaping Cai
Exposure assessments of bisphenol S and F
published pages: , ISSN: , DOI:
2020-04-22
2017 Patrick Fitzgerald
Aggregate and cumulative exposure assessment of the endocrine disrupting chemicals 4-nonylphenol and bis(2-ethylhexyl)-phthalate
published pages: , ISSN: , DOI:
2020-04-22
2018 H. Dirven, M. Andreassen, C. Karrer, N. von Goetz, A.K. Sakhi, T. Husøy
Case study: Exposure to mixtures of chemicals in a human study and verification of aggregated exposure models with real-life data
published pages: S2, ISSN: 0378-4274, DOI: 10.1016/j.toxlet.2018.06.011
Toxicology Letters 295 2020-04-22
2017 Frederic Y. Bois, Nazanin Golbamaki-Bakhtyari, Simona Kovarich, Cleo Tebby, Henry A. Gabb, Emmanuel Lemazurier
High-Throughput Analysis of Ovarian Cycle Disruption by Mixtures of Aromatase Inhibitors
published pages: 77012, ISSN: 0091-6765, DOI: 10.1289/ehp742
Environmental Health Perspectives 125/7 2020-04-22
2018 Zhehui Chen
Review on Cumulative Risk Assessments of Endocrine Disrupting Chemicals
published pages: , ISSN: , DOI:
2020-04-22
2017 Raju Prasad Sharma, Marta Schuhmacher, Vikas Kumar
Development and validation of PBPK model for DEHP and its metabolites: Application to cohort and case–control studies
published pages: S284, ISSN: 0378-4274, DOI: 10.1016/j.toxlet.2017.07.796
Toxicology Letters 280 2020-04-22
2016 Klara Hauser
Chemical-induced steatosis in an in vitro human liver cell model
published pages: 1-36, ISSN: , DOI:
Bachelor’s Thesis ETH Zurich, Department D-HEST 2020-04-22
2016 Pascale Folini
Cellular and molecular correlates of cyproconazole-induced steatosis and inflammation in an in vitro model of human liver cells
published pages: 1-98, ISSN: , DOI:
Master’s Thesis ETH Zurich, Department D-HEST 2020-04-22
2017 Raju Prasad Sharma, Marta Schuhmacher, Vikas Kumar
Review on crosstalk and common mechanisms of endocrine disruptors: Scaffolding to improve PBPK/PD model of EDC mixture
published pages: 1-14, ISSN: 0160-4120, DOI: 10.1016/j.envint.2016.09.016
Environment International 99 2020-04-22

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The information about "EUROMIX" are provided by the European Opendata Portal: CORDIS opendata.

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