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EuroMix SIGNED

EuroMix

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

EuroMix project word cloud

Explore the words cloud of the EuroMix project. It provides you a very rough idea of what is the project "EuroMix" about.

scientific mixtures policies openly liver prioritisation groups innovation tiered boost participation multiple life full strategy sound experiments training verified accessible toolbox ultimately proof cumulative mechanism evaluation chemical hazard model foods dimension endpoints web silico hormones mode safety risks balances playing laboratory animals health vivo chemicals experts exposure facilitated risk private epa helping alimentarius international food euromix criteria written harmonisation models bioassay tools bioassays gender categorisation guidance vitro benefits mixture takes sources platform clear made stages basis global codex grouping stakeholders experimentally action immunology public innovative reduce refined

Project "EuroMix" data sheet

The following table provides information about the project.

Coordinator	RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU Organization address address: Antonie Van Leeuwenhoeklaan 9 city: BILTHOVEN postcode: 3721 MA website: www.rivm.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Netherlands [NL]
Project website	https://www.euromixproject.eu
Total cost	8˙821˙295 €
EC max contribution	7˙999˙097 € (91%)
Programme	1. H2020-EU.3.2. (SOCIETAL CHALLENGES - Food security, sustainable agriculture and forestry, marine, maritime and inland water research, and the bioeconomy)
Code Call	H2020-SFS-2014-2
Funding Scheme	RIA
Starting year	2015
Duration (year-month-day)	from 2015-05-15 to 2019-05-14

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU Organization address address: Antonie Van Leeuwenhoeklaan 9 city: BILTHOVEN postcode: 3721 MA website: www.rivm.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (BILTHOVEN)	coordinator	1˙024˙699.00
2	STICHTING WAGENINGEN RESEARCH STICHTING WAGENINGEN RESEARCH Organization address address: DROEVENDAALSESTEEG 4 city: WAGENINGEN postcode: 6708 PB website: http://www.wageningenur.nl/nl.htm contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (WAGENINGEN)	participant	1˙186˙874.00
3	BUNDESINSTITUT FUER RISIKOBEWERTUNG BUNDESINSTITUT FUER RISIKOBEWERTUNG Organization address address: MAX DOHRN STRASSE 8-10 city: BERLIN postcode: 10589 website: www.bfr.bund.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (BERLIN)	participant	797˙875.00
4	UNIVERSITA DEGLI STUDI DI MILANO UNIVERSITA DEGLI STUDI DI MILANO Organization address address: Via Festa Del Perdono 7 city: MILANO postcode: 20122 website: www.unimi.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (MILANO)	participant	592˙538.00
5	FOLKEHELSEINSTITUTTET FOLKEHELSEINSTITUTTET Organization address address: LOVISENBERGGATA 8 city: OSLO postcode: 456 website: www.fhi.no contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NO (OSLO)	participant	497˙738.00
6	KAROLINSKA INSTITUTET KAROLINSKA INSTITUTET Organization address address: Nobels Vag 5 city: STOCKHOLM postcode: 17177 website: www.ki.se contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (STOCKHOLM)	participant	484˙702.00
7	AGENCE NATIONALE DE LA SECURITE SANITAIRE DE L ALIMENTATION DE L ENVIRONNEMENT ET DU TRAVAIL AGENCE NATIONALE DE LA SECURITE SANITAIRE DE L ALIMENTATION DE L ENVIRONNEMENT ET DU TRAVAIL Organization address address: 14 RUE PIERRE ET MARIE CURIE city: MAISONS ALFORT postcode: 94700 website: www.anses.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (MAISONS ALFORT)	participant	449˙286.00
8	UNIVERSITAT ROVIRA I VIRGILI UNIVERSITAT ROVIRA I VIRGILI Organization address address: CARRER DE ESCORXADOR city: TARRAGONA postcode: 43003 website: http://www.urv.cat contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (TARRAGONA)	participant	425˙720.00
9	FERA SCIENCE LIMITED FERA SCIENCE LIMITED Organization address address: 30 BERNERS STREET city: LONDON postcode: W1T 3LR website: www.fera.co.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	371˙039.00
10	UNIVERSITEIT GENT UNIVERSITEIT GENT Organization address address: SINT PIETERSNIEUWSTRAAT 25 city: GENT postcode: 9000 website: http://www.ugent.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (GENT)	participant	348˙958.00
11	INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT Organization address address: Rue De L'Universite 147 city: PARIS CEDEX 07 postcode: 75338 website: www.inra.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS CEDEX 07)	participant	348˙341.00
12	MATIS OHF MATIS OHF Organization address address: VINLANDSLEID 12 city: REYKJAVIK postcode: 113 website: www.matis.is contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IS (REYKJAVIK)	participant	313˙681.00
13	INSTITUT NATIONAL DE L ENVIRONNEMENT ET DES RISQUES INERIS INSTITUT NATIONAL DE L ENVIRONNEMENT ET DES RISQUES INERIS Organization address address: Parc Technologique Alata city: VERNEUIL EN HALATTE postcode: 60550 website: www.ineris.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (VERNEUIL EN HALATTE)	participant	298˙144.00
14	IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE Organization address address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD city: LONDON postcode: SW7 2AZ website: http://www.imperial.ac.uk/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	297˙500.00
15	BENAKI PHYTOPATHOLOGICAL INSTITUTE BENAKI PHYTOPATHOLOGICAL INSTITUTE Organization address address: Stefanou Delta street 8 city: ATHINA postcode: 14561 website: www.bpi.gr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (ATHINA)	participant	249˙633.00
16	STATNI ZDRAVOTNI USTAV STATNI ZDRAVOTNI USTAV Organization address address: Srobarova 48 city: PRAHA 10 postcode: 10042 website: www.szu.cz contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CZ (PRAHA 10)	participant	75˙093.00
17	DANMARKS TEKNISKE UNIVERSITET DANMARKS TEKNISKE UNIVERSITET Organization address address: ANKER ENGELUNDSVEJ 1 BYGNING 101 A city: KGS LYNGBY postcode: 2800 website: www.dtu.dk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DK (KGS LYNGBY)	participant	74˙982.00
18	NACIONALNI INSTITUT ZA JAVNO ZDRAVJE NACIONALNI INSTITUT ZA JAVNO ZDRAVJE Organization address address: TRUBARJEVA CESTA 2 city: LJUBLJANA postcode: 1000 website: www.nijz.si contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SI (LJUBLJANA)	participant	50˙313.00
19	Ministry of Health of the Republic of Cyprus Ministry of Health of the Republic of Cyprus Organization address address: 1 Prodromou Street & 17 Chilonos Street 1 & 17 city: Nicosia postcode: 1448 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CY (Nicosia)	participant	50˙000.00
20	EUROPEAN FRESH PRODUCE ASSOCIATION AISBL EUROPEAN FRESH PRODUCE ASSOCIATION AISBL Organization address address: RUE DE TREVES 49-51 city: BRUXELLES postcode: 1040 website: www.freshfel.org contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (BRUXELLES)	participant	48˙750.00
21	HEALTH AND SAFETY EXECUTIVE HEALTH AND SAFETY EXECUTIVE Organization address address: MERTON ROAD, REDGRAVE COURT city: BOOTLE MERSEYSIDE postcode: L20 7HS website: http://www.hse.gov.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (BOOTLE MERSEYSIDE)	participant	13˙229.00
22	EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH Organization address address: Raemistrasse 101 city: ZUERICH postcode: 8092 website: https://www.ethz.ch/de.html contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (ZUERICH)	participant	0.00
23	THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS Organization address address: Area 1A, Nobel House, Smith Square 17 city: LONDON postcode: SW1P 3JR website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	0.00

Map

Project objective

Euromix aim to develop an experimentally verified, tiered strategy for the risk assessment of mixtures of multiple chemicals derived from multiple sources across different life stages. The project takes account of the gender dimension and balances the risk of chemicals present in foods against the benefits of those foods. Important concepts for this new strategy are prioritisation criteria for chemicals based on their exposure and hazard characteristics and evaluation of the role of mode of action in grouping chemicals into cumulative assessment groups. In-silico and in-vitro tools will be developed and verified against in-vivo experiments, with focus on four selected endpoints (liver, hormones, development and immunology) to provide a full proof-of-principle. The EuroMix project will result in an innovative platform of bioassays for mixture testing and refined categorisation of chemicals in cumulative assessment groups. New hazard and exposure models will be embedded in a model toolbox, made available for stakeholders through an openly accessible web-based platform. Access to the web-based tools will be facilitated by training. Criteria will be set and guidance will be written on how to use and implement the tiered test strategy. Dissemination and harmonisation of the approach within EU, Codex Alimentarius, and WHO will be achieved by involving a.o. WHO and US-EPA in the project and by the participation of experts playing a key role in helping establish international food safety policies. It is expected that the new mechanism-based strategy, the bioassay platform, the openly accessible web-based model toolbox, and clear guidance on a tiered hazard and exposure test and risk assessment strategy will boost innovation in the public and private sector, provide a sound scientific basis for managing risks to public health from chemical mixtures, ultimately reduce the use of laboratory animals, and support the global discussion of risk assessment policies for mixtures.

Deliverables

List of deliverables.
Specific recommendations regarding implementation of a mechanism-based test strategy for liver, developmental and endocrine for OECD	Documents, reports	2020-04-22 09:35:07
Report on the comparative outcome of using new mechanism-based testing and consequences for animal testing and uncertainties in risk assessment	Documents, reports	2020-04-22 09:35:07
Report of WHO consultation workshop and feasibility study	Documents, reports	2020-04-22 09:35:07
Minutes of meetings with External Advisory Board	Documents, reports	2020-04-22 09:35:07
Scientific paper ready for submission describing the PB-PK/D model approach	Documents, reports	2020-04-22 09:35:07
Scientific article ready for publication describing the method to identify mixtures	Documents, reports	2020-04-22 09:35:06
Report with recommendation for OECD and other international organisations	Documents, reports	2020-04-22 09:35:07
Scientific article describing the PB-PK model for combined exposures	Documents, reports	2020-04-22 09:35:06
Scientific paper ready for submission describing biomarker study	Documents, reports	2020-04-22 09:35:07
Final version of EuroMix model toolbox including hazard and PB-PK/D models	Other	2020-04-22 09:35:07
PB-PK/D modelling for the index compound of the chosen endpoints	Other	2020-04-22 09:35:06
Minutes of meetings with Scientific Advisory Board	Documents, reports	2020-04-22 09:35:07
Scientific article ready for submission describing the results of the in vitro testing of mixtures	Documents, reports	2020-04-22 09:35:07
Report on stakeholder workshop 1	Documents, reports	2020-04-22 09:35:07
Report describing the methodology and results of the refine and retain approach	Documents, reports	2020-04-22 09:35:07
Demonstration tool cumulative exposure assessment	Demonstrators, pilots, prototypes	2020-04-22 09:35:06
Scientific paper ready for submission on models and software for QIVIVE and AOP	Documents, reports	2020-04-22 09:35:07
Scientific article ready for submission describing the in vitro testing strategy for immune toxicity	Documents, reports	2020-04-22 09:35:06
Validation of the aggregated model and comparison with USA software	Documents, reports	2020-04-22 09:35:07
Scientific article ready for submission describing the case study for aggregated exposure assessment	Documents, reports	2020-04-22 09:35:06
Report on stakeholder workshop 2	Documents, reports	2020-04-22 09:35:07
Guidance on the use of the new strategy for tiered testing and assessment	Documents, reports	2020-04-22 09:35:07
Plan for the dissemination and exploitation of the results from EuroMix	Documents, reports	2020-04-22 09:35:07
Scientific article ready for publication balancing risk of mixtures against benefits	Documents, reports	2020-04-22 09:35:07
Proceedings and training material from first training session for stakeholders	Demonstrators, pilots, prototypes	2020-04-22 09:35:07
Scientific article ready for publication describing the in vivo studies	Documents, reports	2020-04-22 09:35:06
Scientific paper ready for submission on the EuroMix toolbox and software	Documents, reports	2020-04-22 09:35:07
The use of QSAR and TTC approaches to prioritise chemicals for mixtures	Documents, reports	2020-04-22 09:35:07
Scientific article ready for submission describing the in vitro testing strategy for developmental/endocrine toxicity	Documents, reports	2020-04-22 09:35:07
Minutes of meetings discussing harmonisation between Europe, EPA and WHO	Documents, reports	2020-04-22 09:35:07
Proceedings and training material from second training session for stakeholders	Demonstrators, pilots, prototypes	2020-04-22 09:35:07
Scientific article rady for submission on cumulative assessment of mixtures of several chemical classes	Documents, reports	2020-04-22 09:35:07
Report on the needs and attitudes of stakeholders to the test strategy	Documents, reports	2020-04-22 09:35:07
Position paper on gaps to be filled in existing legislation	Documents, reports	2020-04-22 09:35:04
Demonstration prototype of EuroMix model toolbox (module priority setting).	Demonstrators, pilots, prototypes	2020-04-22 09:35:04
Informative posters and booklets/brochures	Websites, patent fillings, videos etc.	2020-04-22 09:35:04
CAG-specific PCR arrays	Other	2020-04-22 09:35:04
Pan for managing and releasing open data	Open Research Data Pilot	2020-04-22 09:35:04
Report usefulness of the TTC concept for risk assessment of mixtures	Documents, reports	2020-04-22 09:35:04
Gender Plan	Documents, reports	2020-04-22 09:35:04
Report describing cumulative assessment groups for a broad range of chemicals, based on information extracted from (literature) databases	Documents, reports	2020-04-22 09:35:04
Report on the use of in-silico methods for the prioritisation of mixtures thereof	Documents, reports	2020-04-22 09:35:04
Website for EuroMix project	Websites, patent fillings, videos etc.	2020-04-22 09:35:04
Scientific article ready for submission describing the in vitro testing strategy for liver toxicity	Documents, reports	2020-04-22 09:35:04

Take a look to the deliverables list in detail: detailed list of EuroMix deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	Marc C. Kennedy, David G. Garthwaite, Waldo J. de Boer, Johannes W. Kruisselbrink Modelling aggregate exposure to pesticides from dietary and crop spray sources in UK residents published pages: 9892-9907, ISSN: 0944-1344, DOI: 10.1007/s11356-019-04440-7	Environmental Science and Pollution Research 26/10	2020-04-22
2018	Charles Laroche, Manoj Aggarwal, Hans Bender, Paul Benndorf, Barbara Birk, Jonathan Crozier, Gianni Dal Negro, Federica De Gaetano, Christian Desaintes, Iain Gardner, Bruno Hubesch, Amaia Irizar, David John, Vikas Kumar, Alfonso Lostia, Irene Manou, Mario Monshouwer, Boris P. MÃ¼ller, Alicia Paini, Kirsty Reid, Timothy Rowan, Magdalini Sachana, Katrin Schutte, Catrina Stirling, Rob Taalman, Leon v Finding synergies for 3Rs â€“ Toxicokinetics and read-across: Report from an EPAA partners\' Forum published pages: 5-21, ISSN: 0273-2300, DOI: 10.1016/j.yrtph.2018.08.006	Regulatory Toxicology and Pharmacology 99	2020-04-22
2016	van der Voet, H; de Boer, W; Kruisselbrink, J; van Lenthe, M; CrÃ©pet, A; Kennedy, M; Sprong, C; van Klaveren, J Deliverable 6.1 - Demonstration prototype of the EuroMix model toolbox published pages: , ISSN: , DOI: 10.5281/zenodo.1066087	1	2020-04-22
2016	van Klaveren, J; Sprong, C; Jongenelen, J; HusÃ¸y, T; Dirven, H; Peijnenburg, A Deliverable 1.2 - Data management plan published pages: , ISSN: , DOI: 10.5281/zenodo.1064629	1	2020-04-22
2016	GunnlaugsdÃ³ttir, H; Jensen, S; GylfadÃ³ttir, K; van Klaveren, J; Sporing, C; Hart, A; Nadal, M; Torrente, M; Garcia, T Deliverable 10.2 - Informative poster and booklet/brochure published pages: , ISSN: , DOI: 10.5281/zenodo.1066863	1	2020-04-22
2016	Rotter, S; Beronius, A; Hanberg, A; Zilliacus, J; Nikolopoulou, D; Machera, K; Solecki, R Deliverable 9.1 - Report on mixtures and implementation strategy in Europe â€“ Assessment of chemical mixtures under consideration of current and future regulatory requirements and scientific approaches published pages: , ISSN: , DOI: 10.5281/zenodo.1067585	1	2020-04-22
2016	Kyriakopoulou, K; Nikolopoulou, D; Machera, K; Peijnenburg, A; Loucaâ€ Christodoulou, D; Hadjiloizou, P; Beronius, A; HÃ¥kansson, H; Hanberg, A; Eberini, I; Rorije, E Deliverable 2.1 - Report describing cumulative assessment groups for a broad range of chemicals, based on information extracted from (literature) databases published pages: , ISSN: , DOI: 10.5281/zenodo.1065327	1	2020-04-22
2016	van Klaveren, J; Sprong, C Deliverable 1.1 â€“ Gender Plan published pages: , ISSN: , DOI: 10.5281/zenodo.1064620	1	2020-04-22
2018	Kennedy, Marc; Hart, Andrew; Roelofs, Victoria; Roelofs, Willem Elicitation Tool 3 published pages: , ISSN: , DOI: 10.5281/zenodo.1243619		2020-04-22
2018	Elena Menegola, Francesca Metruccio, Maria Battistoni, Francesca Di Renzo, Angelo Moretto Concentration-response analysis of data obtained in mouse foetuses exposed in utero at E8 to azole antifungals (cyproconazole and triadimefon) alone or in mixture published pages: 21, ISSN: 0890-6238, DOI: 10.1016/j.reprotox.2018.06.080	Reproductive Toxicology 80	2020-04-22
2016	GunnlaugsdÃ³ttir, H; Jensen, S; van Klaveren, J; Zilliacus, J; Durinck, S Deliverable 10.3 - Plan for the dissemination and exploitation of the results from EuroMix published pages: , ISSN: , DOI: 10.5281/zenodo.1066887	1	2020-04-22
2017	Sharon Compeer Effects of chemical mixtures on the development of the head skeleton of zebrafish embryos and on sexual development of the zebrafish published pages: , ISSN: , DOI:		2020-04-22
2016	Remco van der Kris Skeletal malformations in zebrafish embryos to assess mixture effects published pages: , ISSN: , DOI:		2020-04-22
2017	Ananditya Nugraha Analysis of Head Skeletal Malformation in Zebrafish Embryos for Chemical Mixture Assessment: phenotype and Mode of Action published pages: , ISSN: , DOI:		2020-04-22
2018	N. GonzÃ¡lez, E. Schreiber, M. Torrente, V. Kumar, J.L. Domingo, M.M. GÃ³mez Assessment of reproductive toxicity of male rats through maternal exposure to dienestrol published pages: S133, ISSN: 0378-4274, DOI: 10.1016/j.toxlet.2018.06.701	Toxicology Letters 295	2020-04-22
2018	S. Rotter, A. Beronius, A. R. Boobis, A. Hanberg, J. van Klaveren, M. Luijten, K. Machera, D. Nikolopoulou, H. van der Voet, J. Zilliacus, R. Solecki Overview on legislation and scientific approaches for risk assessment of combined exposure to multiple chemicals: the potential EuroMix contribution published pages: 796-814, ISSN: 1040-8444, DOI: 10.1080/10408444.2018.1541964	Critical Reviews in Toxicology 48/9	2020-04-22
2019	Francesca Di Renzo, Francesca Metruccio, Maria Battistoni, Angelo Moretto, Elena Menegola Relative potency ranking of azoles altering craniofacial morphogenesis in rats: An in vitro data modelling approach published pages: 553-560, ISSN: 0278-6915, DOI: 10.1016/j.fct.2018.12.004	Food and Chemical Toxicology 123	2020-04-22
2018	Claudia Luckert, Albert Braeuning, Georges de Sousa, Sigrid Durinck, Efrosini S. Katsanou, Parthena Konstantinidou, Kyriaki Machera, Emanuela S. Milani, Ad A. C. M. Peijnenburg, Roger Rahmani, Andreja Rajkovic, Deborah Rijkers, Anastasia Spyropoulou, Marianna Stamou, Geert Stoopen, Shana Sturla, Bernd Wollscheid, Nathalie Zucchini-Pascal, Alfonso Lampen Adverse Outcome Pathway-Driven Analysis of Liver Steatosis in Vitro : A Case Study with Cyproconazole published pages: 784-798, ISSN: 0893-228X, DOI: 10.1021/acs.chemrestox.8b00112	Chemical Research in Toxicology 31/8	2020-04-22
2019	AmÃ©lie CrÃ©pet, Marie Vanacker, Corinne Sprong, Waldo de Boer, Urska Blaznik, Marc Kennedy, Chris Anagnostopoulos, Despo Louca Christodoulou, JiÅ™Ã Ruprich, Irena Rehurkova, JosÃ© Luis Domingo, Bodil Hamborg Jensen, Francesca Metruccio, Angelo Moretto, Liesbeth Jacxsens, Pieter Spanoghe, David Senaeve, Hilko van der Voet, Jacob van Klaveren Selecting mixtures on the basis of dietary exposure and hazard data: application to pesticide exposure in the European population in relation to steatosis published pages: 291-306, ISSN: 1438-4639, DOI: 10.1016/j.ijheh.2018.12.002	International Journal of Hygiene and Environmental Health 222/2	2020-04-22
2016	Jeroen Meijer A method to evaluate skeletal malformations in zebrafish embryos (in view of mixture toxicity assessment) published pages: , ISSN: , DOI:		2020-04-22
2019	Maria Battistoni, Francesca Di Renzo, Elena Menegola, Frederic Yves Bois Quantitative AOP based teratogenicity prediction for mixtures of azole fungicides published pages: 72-81, ISSN: 2468-1113, DOI: 10.1016/j.comtox.2019.03.004	Computational Toxicology 11	2020-04-22
2018	M. Battistoni, F. Di Renzo, F. Metruccio, A. Moretto, E. Menegola Relative potency ranking of azoles altering cranio-facial morphogenesis in rat: an in vitro data modelling approach published pages: S193, ISSN: 0378-4274, DOI: 10.1016/j.toxlet.2018.06.868	Toxicology Letters 295	2020-04-22
2018	R.P. Sharma, M. Schuhmacher, V. Kumar PBPK/PD coupled HPG SB model to analyze the reproductive toxicity of EDs: Case study on mixture effects of DEHP and TCDD published pages: S249, ISSN: 0378-4274, DOI: 10.1016/j.toxlet.2018.06.1023	Toxicology Letters 295	2020-04-22
2016	Anke Boersma The effect of mixtures on the development of the zebrafish published pages: , ISSN: , DOI:		2020-04-22
2018	Raju Prasad Sharma, Marta Schuhmacher, Vikas Kumar Development of a human physiologically based pharmacokinetic (PBPK) model for phthalate (DEHP) and its metabolites: A bottom up modeling approach published pages: 152-162, ISSN: 0378-4274, DOI: 10.1016/j.toxlet.2018.06.1217	Toxicology Letters 296	2020-04-22
2018	Jan-Jaap Sirks Mode of action definition in the context of mixture effects on skeletal development in zebrafish embryos published pages: , ISSN: , DOI:		2020-04-22
2015	GunnlaugsdÃ³ttir, H; Jensen, S Deliverable 10.1 â€“ Website for EuroMix project published pages: , ISSN: , DOI: 10.5281/zenodo.1066786	1	2020-04-22
2019	Paul van Ommeren Application of the dose addition model in complex mixture risk assessment published pages: , ISSN: , DOI:		2020-04-22
2019	Carina Sujan Gene expression patterns in zebrafish as an endpoint for the development of craniofacial aberrations caused by (environmental) pollutants published pages: , ISSN: , DOI:		2020-04-22
2018	Vivianne Veenma Analysis of the Mode of Action of chemicals inducing head skeletal malformations in zebrafish embryos published pages: , ISSN: , DOI:		2020-04-22
2019	Karrer, Cecile Consumer Exposure to Bisphenolic Compounds: Advancing Exposure and Pharmacokinetic Modeling published pages: , ISSN: , DOI: 10.3929/ethz-b-000336637		2020-04-22
2019	Karrer, Cecile; von Goetz, Natalie; HungerbÃ¼hler, Konrad; Bokkers, Bas; Delmaar, Christiaan PACEM. Shiny beta version 0.9. published pages: , ISSN: , DOI:		2020-04-22
2018	Yvonne C. M. Staal, Jeroen Meijer, Remco J. C. van der Kris, Annamaria C. de Bruijn, Anke Y. Boersma, Eric R. Gremmer, Edwin P. Zwart, Piet K. Beekhof, Wout Slob, Leo T. M. van der Ven Head skeleton malformations in zebrafish (Danio rerio) to assess adverse effects of mixtures of compounds published pages: 3549-3564, ISSN: 0340-5761, DOI: 10.1007/s00204-018-2320-y	Archives of Toxicology 92/12	2020-04-22
2017	Raju Prasad Sharma, Marta Schuhmacher, Vikas Kumar Developing integrated PBPK/PD coupled mechanistic pathway model (miRNA-BDNF): An approach towards system toxicology published pages: 79-91, ISSN: 0378-4274, DOI: 10.1016/j.toxlet.2017.08.003	Toxicology Letters 280	2020-04-22
2018	Monica Andreassen, Hege Hjertholm, Hubert Dirven and Trine HusÃ¸y Real-Life Exposure to Mixtures of Chemicals in the Euromix Human Biomonitoring Study: Results from Repeated 24-Hour Diaries Reporting the Use of Personal Care Products published pages: Society of Toxic, ISSN: , DOI:	Toxicologist Database Toxicologist Database	2020-04-22
2016	Thomas Roiss PBPK Modelling of BPA & BPF published pages: , ISSN: , DOI:		2020-04-22
2016	Nicole Cramer Physiologically based pharmacokinetic modelling of Bisphenol A in humans published pages: , ISSN: , DOI:		2020-04-22
2016	Sharma, R. P., Schuhmacher. M. Kumar V., Developing PBPK/PD model to characterize the mixture effect of TCDD and DEHP altering estradiol kinetic in ovary via crosstalk mechanism published pages: , ISSN: , DOI:		2020-04-22
2018	Charles Laroche, Manoj Aggarwal, Hans Bender, Paul Benndorf, Barbara Birk, Jonathan Crozier, Gianni Dal Negro, Federica De Gaetano, Christian Desaintes, Iain Gardner, Bruno Hubesch, Amaia Irizar, David John, Vikas Kumar, Alfonso Lostia, Irene Manou, Mario Monshouwer, Boris P. MÃ¼ller, Alicia Paini, Kirsty Reid, Timothy Rowan, Magdalini Sachana, Katrin Schutte, Catrina Stirling, Rob Taalman, Leon van Aerts, Renate Weissenhorn, Ursula G. Sauer Finding synergies for 3Rs â€“ Toxicokinetics and read-across: Report from an EPAA partners\' Forum published pages: 5-21, ISSN: 0273-2300, DOI: 10.1016/j.yrtph.2018.08.006	Regulatory Toxicology and Pharmacology 99	2020-04-22
2018	Monica Andreassen, Cecile Karrer, Natalie von Goetz, Amrit K. Sakhi, Hubert Dirven and Trine HusÃ¸y S01.04.07. Verification of Aggregated Exposure to Bisphenols from Diet and Cosmetics - The Human Biomonitoring Study from the EU Project Euromix published pages: , ISSN: , DOI:		2020-04-22
2016	Yaping Cai Exposure assessments of bisphenol S and F published pages: , ISSN: , DOI:		2020-04-22
2017	Patrick Fitzgerald Aggregate and cumulative exposure assessment of the endocrine disrupting chemicals 4-nonylphenol and bis(2-ethylhexyl)-phthalate published pages: , ISSN: , DOI:		2020-04-22
2018	H. Dirven, M. Andreassen, C. Karrer, N. von Goetz, A.K. Sakhi, T. HusÃ¸y Case study: Exposure to mixtures of chemicals in a human study and verification of aggregated exposure models with real-life data published pages: S2, ISSN: 0378-4274, DOI: 10.1016/j.toxlet.2018.06.011	Toxicology Letters 295	2020-04-22
2017	Frederic Y. Bois, Nazanin Golbamaki-Bakhtyari, Simona Kovarich, Cleo Tebby, Henry A. Gabb, Emmanuel Lemazurier High-Throughput Analysis of Ovarian Cycle Disruption by Mixtures of Aromatase Inhibitors published pages: 77012, ISSN: 0091-6765, DOI: 10.1289/ehp742	Environmental Health Perspectives 125/7	2020-04-22
2018	Zhehui Chen Review on Cumulative Risk Assessments of Endocrine Disrupting Chemicals published pages: , ISSN: , DOI:		2020-04-22
2017	Raju Prasad Sharma, Marta Schuhmacher, Vikas Kumar Development and validation of PBPK model for DEHP and its metabolites: Application to cohort and caseâ€“control studies published pages: S284, ISSN: 0378-4274, DOI: 10.1016/j.toxlet.2017.07.796	Toxicology Letters 280	2020-04-22
2016	Klara Hauser Chemical-induced steatosis in an in vitro human liver cell model published pages: 1-36, ISSN: , DOI:	Bachelorâ€™s Thesis ETH Zurich, Department D-HEST	2020-04-22
2016	Pascale Folini Cellular and molecular correlates of cyproconazole-induced steatosis and inflammation in an in vitro model of human liver cells published pages: 1-98, ISSN: , DOI:	Masterâ€™s Thesis ETH Zurich, Department D-HEST	2020-04-22
2017	Raju Prasad Sharma, Marta Schuhmacher, Vikas Kumar Review on crosstalk and common mechanisms of endocrine disruptors: Scaffolding to improve PBPK/PD model of EDC mixture published pages: 1-14, ISSN: 0160-4120, DOI: 10.1016/j.envint.2016.09.016	Environment International 99	2020-04-22

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The information about "EUROMIX" are provided by the European Opendata Portal: CORDIS opendata.

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