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Opendata, web and dolomites

PREDICT SIGNED

A new era in personalised medicine: Radiomics as decision support tool for diagnostics and theragnostics in oncology

Total Cost €

EC-Contrib. €

Partnership

Views

PREDICT project word cloud

Explore the words cloud of the PREDICT project. It provides you a very rough idea of what is the project "PREDICT" about.

personalised radiomics images builds respective boost analytics right accurately capture uses drive actual clinic invasive decisions linked guidance prediction big algorithms unmet understand data newly hampers innovators extraction stratification standard multifactorial train types medicine diagnosis imperative therapy virtually throughput generate care profile treatment 15 signatures esrs phenotypic outcomes detect dss radiographic tumour absent genomic automatic technologies patient assessing biology clinical heterogeneity solutions assist decision mission influences translate oncology diagnostic tool predict clinicians tools amounts medical trained guide huge genetic academic imaging pioneers experts cancer degree deployment

Project "PREDICT" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITEIT MAASTRICHT Organization address address: Minderbroedersberg 4-6 city: MAASTRICHT postcode: 6200 MD website: http://www.maastrichtuniversity.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Netherlands [NL]
Total cost	3˙860˙059 €
EC max contribution	3˙860˙059 € (100%)
Programme	1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
Code Call	H2020-MSCA-ITN-2017
Funding Scheme	MSCA-ITN-ETN
Starting year	2017
Duration (year-month-day)	from 2017-10-01 to 2021-09-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITEIT MAASTRICHT UNIVERSITEIT MAASTRICHT Organization address address: Minderbroedersberg 4-6 city: MAASTRICHT postcode: 6200 MD website: http://www.maastrichtuniversity.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (MAASTRICHT)	coordinator	510˙748.00
2	INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE Organization address address: RUE DE TOLBIAC 101 city: PARIS postcode: 75654 website: www.inserm.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	525˙751.00
3	FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI Organization address address: Via Venezian 1 city: Milan postcode: 20133 website: www.istitutotumori.mi.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (Milan)	participant	516˙122.00
4	ONCORADIOMICS ONCORADIOMICS Organization address address: AVENUE DE L'HOPITAL 1 B34 city: LIEGE postcode: 4000 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (LIEGE)	participant	501˙120.00
5	DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG Organization address address: IM NEUENHEIMER FELD 280 city: HEIDELBERG postcode: 69120 website: www.dkfz.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (HEIDELBERG)	participant	498˙432.00
6	MIRADA MEDICAL LTD MIRADA MEDICAL LTD Organization address address: NEW ROAD OCFI city: OXFORD postcode: OX1 1BY website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (OXFORD)	participant	273˙287.00
7	PERSPECTUM DIAGNOSTICS LTD PERSPECTUM DIAGNOSTICS LTD Organization address address: 23-38 HYTHE BRIDGE STREET BEAVER HOUSE city: OXFORD postcode: OX1 2ET website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (OXFORD)	participant	273˙287.00
8	ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM Organization address address: DR MOLEWATERPLEIN 40 city: ROTTERDAM postcode: 3015 GD website: www.erasmusmc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (ROTTERDAM)	participant	255˙374.00
9	HEALTH INNOVATION VENTURES BV HEALTH INNOVATION VENTURES BV Organization address address: OXFORDLAAN 55 BIOPARTNER GEBOUW city: MAASTRICHT postcode: 6229 EV website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (MAASTRICHT)	participant	255˙374.00
10	UNIVERSITE DE LIEGE UNIVERSITE DE LIEGE Organization address address: PLACE DU 20 AOUT 7 city: LIEGE postcode: 4000 website: www.ulg.ac.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (LIEGE)	participant	250˙560.00
11	DualTpharma DualTpharma Organization address address: OXFORDLAAN 55 city: MAASTRICHT postcode: 6229 EV website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (MAASTRICHT)	partner	0.00
12	ELSEVIER BV ELSEVIER BV Organization address address: RADARWEG 29 city: AMSTERDAM postcode: 1043NX website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM)	partner	0.00
13	EUROPEAN CANCER PATIENT COALITION EUROPEAN CANCER PATIENT COALITION Organization address address: RUE MONTOYER 40 city: BRUXELLES postcode: 1000 website: www.ecpc-online.org contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (BRUXELLES)	partner	0.00
14	HEIDELBERGER IONENSTRAHL THERAPIE (HIT) BETRIEBS GESELLSCHAFT AM UNIVERSITATSKLINIKUM HEIDELBERG MIT BESCHRANKTER HAFTUNG HEIDELBERGER IONENSTRAHL THERAPIE (HIT) BETRIEBS GESELLSCHAFT AM UNIVERSITATSKLINIKUM HEIDELBERG MIT BESCHRANKTER HAFTUNG Organization address address: IM NEUENHEIMER FELD 450 city: HEIDELBERG postcode: 69120 website: www.klinikum.uni-heidelberg.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (HEIDELBERG)	partner	0.00
15	Siemens Siemens Organization address address: n.a. city: Munich postcode: n.a. website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (Munich)	partner	0.00
16	TTOPSTART BV TTOPSTART BV Organization address address: EUCLIDESLAAN 1 city: UTRECHT postcode: 3584 BL website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (UTRECHT)	partner	0.00
17	Universita' Cattolica S. Cuore, Roma Universita' Cattolica S. Cuore, Roma Organization address address: n.a. city: Roma postcode: n.a. website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (Roma)	partner	0.00
18	UNIVERSITATSKLINIKUM HEIDELBERG UNIVERSITATSKLINIKUM HEIDELBERG Organization address address: IM NEUENHEIMER FELD 672 city: HEIDELBERG postcode: 69120 website: www.klinikum.uni-heidelberg.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (HEIDELBERG)	partner	0.00

Map

Project objective

The high degree of tumour (genomic and phenotypic) heterogeneity influences patient’s response to therapy and hampers wide deployment of personalised medicine for cancer treatment. Thus, there is an imperative need for new technologies that can accurately detect tumour heterogeneity, allow for patient stratification and assist clinicians in providing the right diagnosis and treatment for the right patient. PREDICT’s mission is to address this huge unmet need. Radiomics, a newly emerging field that uses high-throughput extraction of large amounts of features from radiographic images, can boost the field of personalised medicine. The analysis of medical images taken as standard-of-care allows Radiomics to capture tumour heterogeneity and to generate ‘tumour-specific’ signatures in a non-invasive way, without the need of assessing the patient’s genetic profile. Thus, Radiomics, if linked to Big- data and decision support systems (DSS), can be used as diagnostic tool for patient stratification, for prediction of treatment response and for guidance, involving the patient, of clinical decisions in oncology. However, researchers that understand cancer biology, advanced imaging and big data analytics are virtually absent. Even more challenging is to translate the outcomes into actual clinical tools involving the patient. PREDICT will train 15 highly promising researchers in the emerging field of Radiomics and Big data. These ESRs will be trained to implement the automatic exploitation of large amounts of imaging data to drive decision-making algorithms that will guide diagnosis and treatment of different types of cancer and to develop ‘tumour-specific’ signatures integrated in multifactorial DSS. The ESRs will become experts and innovators in Radiomics, Big Data and DSS, which will allow them to bring unique solutions towards the clinic. PREDICT builds upon a strong consortium with 8 academic and 10 non-academic partners that are all pioneers in their respective field.

Publications

List of publications.
year	authors and title	journal	last update
2019	(2) Janna E. van Timmeren, Wouter van Elmpt, Ralph T.H.Leijenaar, Bart Reymen, RenÃ© Monshouwer, Johan Bussink, Leen Paelinck, Evelien Bogaert, Carlos De Wagter, Elamin Elhaseen, Yolande Lievens, Olfred Hanseneg, Carsten Brink, Philippe Lambin Longitudinal radiomics of cone-beam CT images from non-small cell lung cancer patients: Evaluation of the added prognostic value for overall survival and locoregional recurrence published pages: , ISSN: 0167-8140, DOI:	Radiotherapy and Oncology 136	2020-01-29
2019	A. Ibrahim, H. C. Woodruff, R, Miclea, A. Jochems, R. van Joep. O. Morin, P. Lambin Radiomics-based malignancy prediction in renal cystic lesions, Research and Patient Safety - Poster published pages: , ISSN: , DOI:	ECR	2020-01-29
2018	A Jochems, RTH Leijenaar, M Bogowicz, FJP Hoebers, F Wesseling, SH Huang, B Chan, JN Waldron, B O\'Sullivan, D Rietveld Combining deep learning and radiomics to predict HPV status in oropharyngeal squamous cell carcinoma published pages: , ISSN: 0167-8140, DOI:	Radiotherapy and Oncology 127	2020-01-29
2019	R. Da-ano, F. Lucia, M. ValliÃ¨res, P. Bonaffini, I. Masson, A. Mervoyer, C. Reinhold, U. Schick, D. Visvikis, M. Hatt Harmonization strategies based on ComBat for mutlicentric radiomics studies published pages: , ISSN: , DOI:		2020-01-29
2017	RTH Leijenaar, M Bogowicz, A Jochems, FJP Hoebers, FWR Wesseling, Sophie H Huang, Biu Chan, John N Waldron, Brian O\'Sullivan, Derek Rietveld, C Rene Leemans, Ruud H Brakenhoff, Oliver Riesterer, Stephanie Tanadini-Lang, Matthias Guckenberger, Kristian Ikenberg, Philippe Lambin Development and validation of a radiomic signature to predict HPV (p16) status from standard CT imaging: a multicenter study published pages: , ISSN: 0007-1285, DOI:	The British journal of radiology 91 (1086)	2020-01-29
2019	A. Iantsen, F. Lucia, M. Ferreira, P. Bonaffini, I. Masson, A. Mervoyer, C. Reinhold, P. Lovinfosse, R. Hustinx, M. De Cuypere, F. Kridelka, U. Schick, D. Visvikis, M. Hatt Automated Cervical Primary Tumor Functional Volume Segmentation in PET Images published pages: , ISSN: , DOI:		2020-01-29
2019	Y. van Wijk, I. Halilaj, E. van Limbergen, S. Walsh, L. Lutgens, P. Lambin, and B. G. L. Vanneste Decision Support Systems in Prostate Cancer Treatment: An Overview published pages: , ISSN: 2314-6141, DOI:	Biomed Research International	2019-12-17

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