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Radiation Innovations for Therapy and Education

Total Cost €


EC-Contrib. €






 RADIATE project word cloud

Explore the words cloud of the RADIATE project. It provides you a very rough idea of what is the project "RADIATE" about.

cured    fails    biological    considerable    area    complementary    technological    cancer    death    microenvironment    tissue    metastases    therapeutic    clinicians    60    effort    methodology    altering    acute    strategies    disease    radiotherapy    platforms    outstanding    technologies    patients    international    expertise    radiobiology    intervention    categories    variety    network    regrowth    competitive    demand    meeting    distant    excellent    combating    benefit    tumor    treatment    radiobiologists    hypotheses    combined    pursuit    eliminate    approximately    health    students    outcome    screening    science    stimulate    radiation    academic    imaging    good    progress    immune    industrial    academics    primary    young    training    sensitivity    fragmented    normal    premise    underrepresented    surrounding    radioresistance    scientists    collaborations    community    routes    45    translational    strengthen    resistance    europe    designed    capability    illness    preclinical    therapy    placed    innovative   

Project "RADIATE" data sheet

The following table provides information about the project.


Organization address
city: OXFORD
postcode: OX1 2JD

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website
 Total cost 3˙081˙061 €
 EC max contribution 3˙081˙061 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2014
 Funding Scheme MSCA-ITN-ETN
 Starting year 2015
 Duration (year-month-day) from 2015-03-01   to  2019-02-28


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
2    INSTITUT CURIE FR (PARIS) participant 525˙751.00
6    UNIVERSITAETSKLINIKUM ESSEN DE (ESSEN) participant 498˙432.00
7    DNA Therapeutics FR (Evry) partner 0.00
8    DualTpharma NL (MAASTRICHT) partner 0.00
9    EACR UK (Nottingham) partner 0.00
10    ESTRO BE (Brussels) partner 0.00
11    MAB Discovery DE (Neuried) partner 0.00
13    University of Szeged US (CAMBRIDGE) partner 0.00
14    Vertex Pharmaceuticals UK (Abingdon) partner 0.00


 Project objective

Approximately 45-60% of all cancer patients are treated with radiotherapy. Some of these patients have a good outcome, but in other cases their illness fails to be cured. This may result from distant metastases or from regrowth of the primary tumor. This training network is built on the premise that considerable advances in understanding radiobiology will open novel routes for effective therapeutic intervention with biological targets to improve the outcome of cancer treatment; this progress requires a European-wide effort. This network of radiobiologists, clinicians and scientists with complementary expertise will stimulate outstanding science, meeting the high demand for excellent young academics enhancing Europe´s competitive capability in this highly relevant but underrepresented and fragmented research area. We will strengthen collaborations and technological platforms to develop effective therapeutic strategies for cancer. The failure to eliminate the primary cancer can be placed into 2 categories: the radioresistance of the tumor and the sensitivity of surrounding normal tissue; and the effects of the tumor microenvironment leading to greater overall resistance and altering the immune response to the tumor. This will be combined with translational work designed to identify and implement new therapeutic strategies for use in radiotherapy. Students will benefit from the expertise of the whole, both academic and industrial including unique research technologies that will now be available throughout the network, including a variety of screening platforms, methodology for preclinical cancer therapy and novel radiation and imaging technologies. The European community will benefit from the pursuit of innovative hypotheses, training of new researchers, and dissemination of knowledge. By combating a major death-related disease in Europe this project will raise health and bring long-term benefit to the European and international community.


List of deliverables.
eLearning modules Websites, patent fillings, videos etc. 2019-07-23 15:24:36
Publications Websites, patent fillings, videos etc. 2019-07-23 15:24:57
Outreach Websites, patent fillings, videos etc. 2019-07-23 15:24:53
PhD completion Other 2019-07-23 15:24:48
Conferences Abstracts Websites, patent fillings, videos etc. 2019-07-23 15:24:54
RADIATE-Gray Symposium Other 2019-07-23 16:17:34
RADIATE International symposium Other 2019-07-23 15:22:52
Dissemination plan Websites, patent fillings, videos etc. 2019-07-09 09:20:58
Manual for publishing data on Websites, patent fillings, videos etc. 2019-07-09 09:20:58
RADIATE-EACR International Conference Other 2019-07-09 09:20:58
Recruitment of ESRs Other 2019-07-09 09:20:58

Take a look to the deliverables list in detail:  detailed list of RADIATE deliverables.


year authors and title journal last update
List of publications.
2018 Rekers, Nicolle H.; Olivo Pimentel, Veronica; Yaromina, Ala; Lieuwes, Natasja G.; Biemans, Rianne; Zegers, Catharina M.L.; Germeraad, Wilfred T.V.; Van Limbergen, Evert J.; Neri, Dario; Dubois, Ludwig J.; Lambin, Philippe
The immunocytokine L19-IL2: An interplay between radiotherapy and long-lasting systemic anti-tumour immune responses
published pages: , ISSN: 2162-402X, DOI: 10.3929/ethz-b-000238558
Oncoimmunology 1 2019-07-09
2019 Valéry L. Payen, Luca X. Zampieri, Paolo E. Porporato, Pierre Sonveaux
Pro- and antitumor effects of mitochondrial reactive oxygen species
published pages: , ISSN: 0167-7659, DOI: 10.1007/s10555-019-09789-2
Cancer and Metastasis Reviews 2019-07-09
2018 Klaudia Szymonowicz, Sebastian Oeck, Adam Krysztofiak, Jansje van der Linden, George Iliakis, Verena Jendrossek
Restraining Akt1 Phosphorylation Attenuates the Repair of Radiation-Induced DNA Double-Strand Breaks and Reduces the Survival of Irradiated Cancer Cells
published pages: 2233, ISSN: 1422-0067, DOI: 10.3390/ijms19082233
International Journal of Molecular Sciences 19/8 2019-07-09
2017 Sebastian Oeck, Nathalie M. Malewicz, Sebastian Hurst, Klaudia Al-Refae, Adam Krysztofiak, Verena Jendrossek
The Focinator v2-0 – Graphical Interface, Four Channels, Colocalization Analysis and Cell Phase Identification
published pages: 114-120, ISSN: 0033-7587, DOI: 10.1667/RR14746.1
Radiation Research 188/1 2019-07-09
2018 Venus Sosa Iglesias, Lorena Giuranno, Ludwig J. Dubois, Jan Theys, Marc Vooijs
Drug Resistance in Non-Small Cell Lung Cancer: A Potential for NOTCH Targeting?
published pages: , ISSN: 2234-943X, DOI: 10.3389/fonc.2018.00267
Frontiers in Oncology 8 2019-07-09
2015 Mohamed Ali Mosrati, Annika Malmström, Malgorzata Lysiak, Adam Krysztofiak, Martin Hallbeck, Peter Milos, Anna-Lotta Hallbeck, Charlotte Bratthäll, Michael Strandéus, Marie Stenmark-Askmalm, Peter Söderkvist
TERT promoter mutations and polymorphisms as prognostic factors in primary glioblastoma
published pages: , ISSN: 1949-2553, DOI: 10.18632/oncotarget.4389
Oncotarget 6/18 2019-07-09
2018 Sebastian Oeck, Klaudia Szymonowicz, Gesa Wiel, Adam Krysztofiak, Jamil Lambert, Benjamin Koska, George Iliakis, Beate Timmermann, Verena Jendrossek
Relating Linear Energy Transfer to the Formation and Resolution of DNA Repair Foci After Irradiation with Equal Doses of X-ray Photons, Plateau, or Bragg-Peak Protons
published pages: 3779, ISSN: 1422-0067, DOI: 10.3390/ijms19123779
International Journal of Molecular Sciences 19/12 2019-07-09
2018 Bastien Doix, Estelle Bastien, Alix Rambaud, Adán Pinto, Caroline Louis, Vincent Grégoire, Olivier Riant, Olivier Feron
Preclinical Evaluation of White Led-Activated Non-porphyrinic Photosensitizer OR141 in 3D Tumor Spheroids and Mouse Skin Lesions
published pages: , ISSN: 2234-943X, DOI: 10.3389/fonc.2018.00393
Frontiers in Oncology 8 2019-07-09
2017 Vincent F. Van Hée, Daniel Labar, Gwenaël Dehon, Debora Grasso, Vincent Grégoire, Giulio G. Muccioli, Raphaël Frédérick, Pierre Sonveaux
\"Radiosynthesis and validation of (±)-[18F]-3-fluoro-2-hydroxypropionate ([18F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumors\"
published pages: , ISSN: 1949-2553, DOI: 10.18632/oncotarget.14705
Oncotarget 2019-07-09
2016 Angela Diana, Lai Mun Wang, Zenobia D’Costa, Paul Allen, Abul Azad, Michael A. Silva, Zahir Soonawalla, Stanley Liu, W. Gillies McKenna, Ruth J. Muschel, Emmanouil Fokas
Prognostic value, localization and correlation of PD-1/PD-L1, CD8 and FOXP3 with the desmoplastic stroma in pancreatic ductal adenocarcinoma
published pages: , ISSN: 1949-2553, DOI: 10.18632/oncotarget.10038
Oncotarget 2019-07-09
2017 Pierre Danhier, Piotr Bański, Valéry L Payen, Debora Grasso, Luigi Ippolito, Pierre Sonveaux, Paolo E Porporato
Cancer metabolism in space and time: Beyond the Warburg effect
published pages: , ISSN: 0005-2728, DOI: 10.1016/j.bbabio.2017.02.001
Biochimica et Biophysica Acta (BBA) - Bioenergetics 2019-07-09
2016 Jhudit Pérez-Escuredo, Vincent F. Van Hée, Martina Sboarina, Jorge Falces, Valéry L. Payen, Luc Pellerin, Pierre Sonveaux
Monocarboxylate transporters in the brain and in cancer
published pages: 2481-2497, ISSN: 0167-4889, DOI: 10.1016/j.bbamcr.2016.03.013
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1863/10 2019-07-09
2016 Angela Diana, Lai Mun Wang, Zenobia D’Costa, Abul Azad, Michael A. Silva, Zahir Soonawalla, Paul Allen, Stanley Liu, W. Gillies McKenna, Ruth J. Muschel, Emmanouil Fokas
Prognostic role and correlation of CA9, CD31, CD68 and CD20 with the desmoplastic stroma in pancreatic ductal adenocarcinoma
published pages: , ISSN: 1949-2553, DOI: 10.18632/oncotarget.12022
Oncotarget 2019-07-09

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