Explore the words cloud of the CRYDIS project. It provides you a very rough idea of what is the project "CRYDIS" about.
The following table provides information about the project.
|Coordinator Country||Denmark [DK]|
|Total cost||216˙000 €|
|EC max contribution||216˙000 € (100%)|
1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
|Duration (year-month-day)||from 2015-01-01 to 2018-12-31|
Take a look of project's partnership.
|1||KOBENHAVNS UNIVERSITET||DK (KOBENHAVN)||coordinator||130˙500.00|
|2||UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK||IE (Cork)||participant||31˙500.00|
|3||PFIZER LIMITED||UK (SANDWICH)||participant||27˙000.00|
|4||PARAYTEC LIMITED||UK (YORK)||participant||18˙000.00|
|5||PION INC.(UK) LTD||UK (FOREST ROW)||participant||9˙000.00|
The CRYDIS exchange programme will establish and support international and inter-sectoral transfer of knowledge and expertise in pharmaceutical and instrument science between several EU research institutes and industrial companies. It will also enhance understanding of the value of inter-sectoral exchange mechanisms for taking research to market. CRYDIS undertakes innovative, collaborative research on the clinically-important topic of dissolution of drug substance particles in bio-relevant media and the undesired subsequent nucleation and re-precipitation of the drug prior to its absorption. Using innovative advances in UV imaging technology, CRYDIS investigates the utility of novel dissolution assays as key tools to obtain fundamental data on the mechanism and kinetics of undesired nucleation and re-precipitation during or following dissolution, a significant problem for the pharmaceutical industry which struggles to obtain sufficient exposure to poorly soluble drug substances to ensure an effective dose is absorbed by the patient. The key technologies in this proposal offer a step change in capability and functionality, offering the potential to undertake more detailed studies of the dissolution/re-precipitation processes relevant to pharmaceutical materials. Access to this key technology and the further development of its capability offers the potential for breakthroughs in development of process understanding and of robust and widely applicable protocols. Additional value is brought to CRYDIS through close working with synergistic European networks, leveraging a greater knowledge input and impact outreach. Running parallel with the science programme, an innovation management work-package analyses effectiveness of the exchange mechanism in building a shared culture, transferring knowledge and developing understanding of processes that drive a product to market. The outcomes of this will be used to advise and drive potential future exchange activities.
|Technical note on new capabilities||Documents, reports||2019-10-28 17:20:03|
|Literature publications for D2.1-D2.4||Documents, reports||2019-10-28 17:20:03|
|Operating parameters for imaging & variability||Demonstrators, pilots, prototypes||2019-10-28 17:20:03|
|Technical data on nucleation rates||Documents, reports||2019-10-28 17:20:03|
|Screening assay for precipitation inhibitors||Demonstrators, pilots, prototypes||2019-10-28 17:20:03|
|Dissolution testing guidelines for UV/Raman||Documents, reports||2019-10-28 17:20:03|
|Literature publications for D3.1 & D3.2||Documents, reports||2019-10-28 17:20:03|
|ATR-(FTIR) & turbidity studies||Demonstrators, pilots, prototypes||2019-10-28 17:20:02|
|pH-UV imaging method||Demonstrators, pilots, prototypes||2019-10-28 17:20:02|
|UV imaging data validation||Demonstrators, pilots, prototypes||2019-10-28 17:20:02|
|Technical report on approaches to SDI||Documents, reports||2019-10-28 17:20:02|
|Optimised UV/Raman experiments||Demonstrators, pilots, prototypes||2019-10-28 17:20:02|
|Prototype light microscopy â€“ UV imaging assay||Demonstrators, pilots, prototypes||2019-10-28 17:20:02|
|Technical report on new capabilities||Documents, reports||2019-10-28 17:20:02|
Take a look to the deliverables list in detail: detailed list of CRYDIS deliverables.
|year||authors and title||journal||last update|
Peter Madelung, Poul Bertelsen, Jette Jacobsen, Anette MÃ¼llertz, Jesper Ã˜stergaard
Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging
published pages: 516-522, ISSN: 1773-2247, DOI: 10.1016/j.jddst.2017.05.010
|Journal of Drug Delivery Science and Technology 39||2019-10-28|
Maria Doreth, Korbinian LÃ¶bmann, Petra Priemel, Holger Grohganz, Robert Taylor, RenÃ© Holm, Heidi Lopez de Diego, Thomas Rades
Influence of PVP molecular weight on the microwave assisted in situ amorphization of indomethacin
published pages: 62-69, ISSN: 0939-6411, DOI: 10.1016/j.ejpb.2017.10.001
|European Journal of Pharmaceutics and Biopharmaceutics 122||2019-10-28|
UV imaging in pharmaceutical analysis
published pages: 140-148, ISSN: 0731-7085, DOI: 10.1016/j.jpba.2017.07.055
|Journal of Pharmaceutical and Biomedical Analysis 147||2019-10-28|
Sabrine S. Jensen, Henrik Jensen, David M. Goodall, Jesper Ã˜stergaard
Performance characteristics of UV imaging instrumentation for diffusion, dissolution and release testing studies
published pages: 113-123, ISSN: 0731-7085, DOI: 10.1016/j.jpba.2016.08.018
|Journal of Pharmaceutical and Biomedical Analysis 131||2019-10-28|
Yu Sun, Jesper Ã˜stergaard
Application of UV Imaging in Formulation Development
published pages: 929-940, ISSN: 0724-8741, DOI: 10.1007/s11095-016-2047-5
|Pharmaceutical Research 34/5||2019-10-28|
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