Opendata, web and dolomites


Sexual Commitment of Malaria Parasites: Investigation Into the Epigenetic Control of Plasmodium Gametocytogenesis

Total Cost €


EC-Contrib. €






Project "SECOMAP" data sheet

The following table provides information about the project.


Organization address
postcode: G12 8QQ

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website
 Total cost 195˙454 €
 EC max contribution 195˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-08-01   to  2017-07-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY OF GLASGOW UK (GLASGOW) coordinator 195˙454.00


 Project objective

Malaria is one of the major threats for human health worldwide and caused by unicellular organisms of the Plasmodium genus. Within their mosquito vector and human host malaria parasites replicate almost exclusively asexually. In order to be transmitted to mosquitoes formerly asexual parasites instead develop into gametocytes, which are the only forms that can infect mosquitoes. Understanding the switch of asexual to sexual replication could offer new routes towards therapeutic intervention in sexual development and transmission. However, the molecular details of commitment to gametocytogenesis remain largely unknown, and only recently the AP2-G transcription factor was identified as master regulator of gametocytogenesis. Gametocyte formation is a dead end for enduring infection and therefore sexual commitment has to be suitably regulated to ensure prolonged infection and transmission at the same time. The proposed research project aims to elucidate the epigenetic mechanisms which controls gametocytogenesis in malaria parasites infectious to rodents and humans, and intends to identify key molecular factors which regulate repression and activation of the ap2-g locus. The project will shed new light on the molecular mechanisms controlling sexual commitment and general gene expression in Plasmodium, with implications for therapeutic intervention in transmission and development of malaria parasites.


year authors and title journal last update
List of publications.
2016 Sebastian Kirchner, B. Joanne Power, Andrew P. Waters
Recent advances in malaria genomics and epigenomics
published pages: , ISSN: 1756-994X, DOI: 10.1186/s13073-016-0343-7
Genome Medicine 8/1 2019-07-24

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "SECOMAP" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email ( and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "SECOMAP" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

NaWaTL (2020)

Narrative, Writing, and the Teotihuacan Language: Exploring Language History Through Phylogenetics, Epigraphy and Iconography

Read More  

CIGNUS (2019)

CuInGaSe Nanowires Under the Sun

Read More  

DEMOS (2019)

Disfluencies and Eye MOvements during Speech: what can they reveal about language production?

Read More