Explore the words cloud of the POSEIDON project. It provides you a very rough idea of what is the project "POSEIDON" about.
The following table provides information about the project.
MEDIZINISCHE HOCHSCHULE HANNOVER
|Coordinator Country||Germany [DE]|
|Total cost||159˙460 €|
|EC max contribution||159˙460 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2015-10-01 to 2017-09-30|
Take a look of project's partnership.
|1||MEDIZINISCHE HOCHSCHULE HANNOVER||DE (HANNOVER)||coordinator||159˙460.00|
Human induced pluripotent stem cells (hiPSCs) have the potential to revolutionize biomedical sciences, however the standardised mass production, indispensable for their industrial and therapeutic use, is still a major challenge. Impeller stirred-tank bioreactors, currently used for hiPSC bioprocessing, impose detrimental stresses on cultured hiPSCs, resulting in heterogeneity of cells and cell-aggregates, limited bioprocess reproducibility, and low hiPSC expansion efficiency at high costs. The ambitious purpose of the POSEIDON project is the development of a next-generation automated bioreactor platform to significantly improve reproducibility, efficiency and cost-effectiveness of scalable hiPSC expansion. To demonstrate the utility of the method for the production of valuable human cell types, a novel process for hiPSC-cardiomyogenic differentiation will also be established. This pioneering bioreactor will be developed by advanced engineering design methods and will enable controlled hiPSC suspension culture by non-impeller-dependent low-shear hydrodynamic conditions. Purposely designed automated systems will lead to bioprocess standardisation with enhanced reproducibility, efficiency and scalability beyond the state in the art. The proposed Fellowship will enable a highly interdisciplinary collaboration between the Researcher, a talented post-doc with a significant track record in bioengineering, and the supervisor, a world leader in stem cell bioprocessing, whose group is embedded in one of Europe’s leading hubs for regenerative biomedicine. These working conditions will effectively promote the Researcher’s professional development, providing her with excellent new expertise in stem cell bioprocessing and fundamental leadership skills, significantly widening her career perspectives. The project outcomes will be of tremendous benefit to the European biomedical and pharmaceutical sectors, contributing to the European excellence, competitiveness and quality of life.
|year||authors and title||journal||last update|
Diana Massai, Emiliano Bolesani, Diana Robles Diaz, Christina Kropp, Henning Kempf, Caroline Halloin, Ulrich Martin, Tudor Braniste, Giuseppe Isu, Vanessa Harms, Umberto Morbiducci, Gerald DrÃ¤ger, Robert Zweigerdt
Sensitivity of human pluripotent stem cells to insulin precipitation induced by peristaltic pump-based medium circulation: considerations on process development
published pages: 1-15, ISSN: 2045-2322, DOI: 10.1038/s41598-017-04158-x
|Scientific Reports 7/1||2019-06-18|
Isotta Chimenti, Diana Massai, Umberto Morbiducci, Antonio Paolo Beltrami, Maurizio Pesce, Elisa Messina
Stem Cell Spheroids and Ex Vivo Niche Modeling: Rationalization and Scaling-Up
published pages: 150-166, ISSN: 1937-5387, DOI: 10.1007/s12265-017-9741-5
|Journal of Cardiovascular Translational Research 10/2||2019-06-18|
Christina Kropp, Diana Massai, Robert Zweigerdt
Progress and challenges in large-scale expansion of human pluripotent stem cells
published pages: 244-254, ISSN: 1359-5113, DOI: 10.1016/j.procbio.2016.09.032
|Process Biochemistry 59||2019-06-18|
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "POSEIDON" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (email@example.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "POSEIDON" are provided by the European Opendata Portal: CORDIS opendata.
Multi-color and single-molecule fluorescence imaging of intraflagellar transport in the phasmid chemosensory cilia of C. ElegansRead More
Narrative, Writing, and the Teotihuacan Language: Exploring Language History Through Phylogenetics, Epigraphy and IconographyRead More
Mathematics AnalogiesRead More