LUCA SIGNED
Laser and Ultrasound Co-Analyzer for thyroid nodules
Total Cost €
0EC-Contrib. €
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0LUCA project word cloud
Explore the words cloud of the LUCA project. It provides you a very rough idea of what is the project "LUCA" about.
Project "LUCA" data sheet
The following table provides information about the project.
| Coordinator |
FUNDACIO INSTITUT DE CIENCIES FOTONIQUES
Organization address contact info |
| Coordinator Country | Spain [ES] |
| Project website | http://www.luca-project.eu/ |
| Total cost | 3˙999˙334 € |
| EC max contribution | 3˙628˙845 € (91%) |
| Programme |
1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT)) |
| Code Call | H2020-ICT-2015 |
| Funding Scheme | IA |
| Starting year | 2016 |
| Duration (year-month-day) | from 2016-02-01 to 2020-07-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | FUNDACIO INSTITUT DE CIENCIES FOTONIQUES | ES (Castelldefels) | coordinator | 1˙048˙730.00 |
| 2 | POLITECNICO DI MILANO | IT (MILANO) | participant | 689˙700.00 |
| 3 | HEMOPHOTONICS SL | ES (CASTELLDEFELS) | participant | 402˙299.00 |
| 4 | EIBIR GEMEINNUTZIGE GMBH ZUR FORDERUNG DER ERFORSCHUNG DER BIOMEDIZINISCHEN BILDGEBUNG | AT (WIEN) | participant | 375˙000.00 |
| 5 | CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER | ES (BARCELONA) | participant | 353˙763.00 |
| 6 | THE UNIVERSITY OF BIRMINGHAM | UK (BIRMINGHAM) | participant | 297˙178.00 |
| 7 | IMV IMAGING FRANCE | FR (ANGOULEME) | participant | 273˙542.00 |
| 8 | VERMON SA | FR (TOURS) | participant | 188˙630.00 |
Map
Project objective
This is a trans-disciplinary project that joins endocrinologists (“end-users”), radiologists (“end-users”), physicists who are experts in medical photonics, engineers who are experts in photonics and ultrasonics and the industry to work towards a concentrated goal - to produce a novel, point-of-care, low-cost, screening device that combines two photonics systems (near-infrared diffuse correlation spectroscopy (DCS) and time-resolved spectroscopy (TRS)) with a multi-modal ultrasound (US) system and a probe that enables multi-modal data acquisition for the screening of thyroid nodules (TN) for thyroid cancer (TC). TN are a common pathology having a prevalence of palpable nodules around 5% in women and 1% in men, that increases to 19-76% with the use of neck US. In screening thyroid nodules, to exclude thyroid cancer which occurs in 5-15% of TN, the first step is the US followed by fine needle aspiration biopsy (FNAB) of suspicious nodules. The sensitivity and specificity of this process in thyroid cancer are limited, with a large number of non-diagnostic and false positive results that lead to unnecessary surgeries. A reduction in the number of surgeries with a point-of-care diagnostic procedure would have an important socio-economic impact, diminishing the number of thyroidectomies and the associated comorbidities. This implies savings of millions of euros per year. Evidence shows that multi-modal approaches that include hemodynamic information leads to better specificity while each modality on its own fails. We hypothesize that a new optical-ultrasound probe and integrated system enabled by the development of novel, key enabling photonic components and sub-systems to provide synergetic information on tissue morphology, composition and function will have a large impact in this field. Our action is directed by end-users who participate in the proposal and will be exploited by the industrial partners who cover the whole value-chain.
Deliverables
| Communication kit update | Documents, reports | 2020-02-28 09:35:32 |
| Report on the dissemination activity Y2 | Documents, reports | 2020-02-28 09:35:32 |
| Fully functional LUCA system | Demonstrators, pilots, prototypes | 2020-02-28 09:35:32 |
| Report on the dissemination activity Y3 | Documents, reports | 2020-02-28 09:35:32 |
| Data Management Plan_new | Open Research Data Pilot | 2020-02-28 09:35:32 |
| Approval by ethical committees | Documents, reports | 2020-02-28 09:35:32 |
| Project web site | Websites, patent fillings, videos etc. | 2020-02-28 09:35:31 |
| Provision of a optical-ultrasound phantom kit | Demonstrators, pilots, prototypes | 2020-02-28 09:35:30 |
| Dissemination material | Websites, patent fillings, videos etc. | 2020-02-28 09:35:30 |
| Project management and quality assurance plan | Documents, reports | 2020-02-28 09:35:30 |
| Project Presentation | Documents, reports | 2020-02-28 09:35:31 |
| Dissemination and communication plan | Documents, reports | 2020-02-28 09:35:31 |
| Data Management Plan | Documents, reports | 2020-02-28 09:35:32 |
| Report on the dissemination activity Y1 | Documents, reports | 2020-02-28 09:35:31 |
| Video | Websites, patent fillings, videos etc. | 2020-02-28 09:35:31 |
Take a look to the deliverables list in detail: detailed list of LUCA deliverables.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2019 |
Marco Renna, Mauro Buttafava, Anurag Behera, Marta Zanoletti, Laura Di Sieno, Alberto Dalla Mora, Davide Contini, Alberto Tosi Eight-Wavelength, Dual Detection Channel Instrument for Near-Infrared Time-Resolved Diffuse Optical Spectroscopy published pages: 1-11, ISSN: 1077-260X, DOI: 10.1109/jstqe.2018.2863570 |
IEEE Journal of Selected Topics in Quantum Electronics 25/1 | 2020-02-28 |
| 2018 |
Lorenzo Cortese, Giuseppe Lo Presti, Marco Pagliazzi, Davide Contini, Alberto Dalla Mora, Antonio Pifferi, Sanathana Konugolu Venkata Sekar, Lorenzo Spinelli, Paola Taroni, Marta Zanoletti, Udo M. Weigel, Sixte de Fraguier, An Nguyen-Dihn, Bogdan Rosinski, Turgut Durduran Liquid phantoms for near-infrared and diffuse correlation spectroscopies with tunable optical and dynamic properties published pages: 2068, ISSN: 2156-7085, DOI: 10.1364/BOE.9.002068 |
Biomedical Optics Express 9/5 | 2020-02-28 |
| 2018 |
Stanislaw Wojtkiewicz, Turgut Durduran, Hamid Dehghani Time-resolved near infrared light propagation using frequency domain superposition published pages: 41, ISSN: 2156-7085, DOI: 10.1364/boe.9.000041 |
Biomedical Optics Express 9/1 | 2020-02-28 |
| 2018 |
Sanathana Konugolu Venkata Sekar, Andrea Farina, Alberto Dalla Mora, Claus Lindner, Marco Pagliazzi, Mireia Mora, Gloria Aranda, Hamid Dehghani, Turgut Durduran, Paola Taroni, Antonio Pifferi Broadband (550–1350 nm) diffuse optical characterization of thyroid chromophores published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-27684-8 |
Scientific Reports 8/1 | 2020-02-28 |
| 2017 |
Mauro Buttafava, Edoardo Martinenghi, Davide Tamborini, Davide Contini, Alberto Dalla Mora, Marco Renna, Alessandro Torricelli, Antonio Pifferi, Franco Zappa, Alberto Tosi A Compact Two-Wavelength Time-Domain NIRS System Based on SiPM and Pulsed Diode Lasers published pages: 1-14, ISSN: 1943-0655, DOI: 10.1109/JPHOT.2016.2632061 |
IEEE Photonics Journal 9/1 | 2020-02-28 |
| 2016 |
E. Martinenghi, L. Di Sieno, D. Contini, M. Sanzaro, A. Pifferi, A. Dalla Mora Time-resolved single-photon detection module based on silicon photomultiplier: A novel building block for time-correlated measurement systems published pages: 73101, ISSN: 0034-6748, DOI: 10.1063/1.4954968 |
Review of Scientific Instruments 87/7 | 2020-02-28 |
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