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NANO-SUPREMI SIGNED

“Tracking nano-bioprocesses using Super-Resolution Microscopy Techniques”

Total Cost €

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EC-Contrib. €

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Partnership

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 NANO-SUPREMI project word cloud

Explore the words cloud of the NANO-SUPREMI project. It provides you a very rough idea of what is the project "NANO-SUPREMI" about.

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Project "NANO-SUPREMI" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA 

Organization address
address: VIA CRACOVIA 50
city: ROMA
postcode: 133
website: www.uniroma2.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
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fax: n.a.

 Coordinator Country Italy [IT]
 Project website https://nanosupremi.fnusa-icrc.org.
 Total cost 873˙000 €
 EC max contribution 724˙500 € (83%)
 Programme 1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
 Code Call H2020-MSCA-RISE-2015
 Funding Scheme MSCA-RISE
 Starting year 2016
 Duration (year-month-day) from 2016-03-01   to  2020-02-29

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA IT (ROMA) coordinator 306˙000.00
2    FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA IT (GENOVA) participant 270˙000.00
3    FAKULTNI NEMOCNICE U SV. ANNY V BRNE CZ (Brno) participant 148˙500.00
4    FUNDACAO UNIVERSIDADE FEDERAL DO ABC BR (SANTO ANDRE) partner 0.00
5    Ministerio de Ciencia, Tecnología y Medio Ambiente CU (La Habana) partner 0.00
6    THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US (OAKLAND CA) partner 0.00
7    UNIVERSITY OF MELBOURNE AU (MELBOURNE) partner 0.00

Map

 Project objective

Long-range research and innovation goal: The long-range goal of Nano-Supremi is to develop case studies to enable the advanced super-resolution microscopy to investigate nanoscale synthetic and biological structures and to probe nanoscale dynamic processes. Long-range biomedical research and technology goal: The implementation of Nano-Supremi will allow for tracking nanometer-scale bioprocesses such as (i) nanomedicines cellular uptake and trafficking and (ii) single-molecule dynamic processes of DNA-protein, (iii) protein-membrane interactions. Key Research Goals: The objective of Nano-Supremi is to turn the following creative research ideas into advanced microscopy technologies and services. This will ultimately results in the evaluation of in vitro protein and DNA activity and therapeutic efficacy of nanomedicines plugging the gap between innovative research and its exploitation in clinical setting. Scientific impact: We identified a few innovative case studies to explore the potentiality of super resolution microscopy techniques in solving nanoscale bio-structures and dynamic processes. Impact on early-stage researchers: Nano-Supremi involves key participation of junior researchers with outstanding record of achievements in education and research, providing strong support for the development of their careers. Intersectoral dimension: A synergistic approach in using advanced technologies developed by microscope manufacturers to answer fundamental and applied questions on bioprocesses will be pursued. Interdisciplinary dimension: A complementary research program, ranging from nanophotonics, materials science, to molecular biology and bio-analytical chemistry, will drive the implementation of research tasks towards the full achievement of the objectives. International dimension: Funding of this program will enable long-term, transformative research collaborations between groups settled in European Countries and in four non-EU Countries (AU, US, Brazil, Cu)

 Deliverables

List of deliverables.
Proceedings and teaching material concerning EU grants Documents, reports 2020-03-11 13:05:38
Submitted grant proposals to European Community, NSF and NIH (USA), ARC Documents, reports 2020-03-11 13:05:35
Lecture notes on advanced microscopy methods and technologies Documents, reports 2020-03-11 13:05:34
Lecture notes and conference presentations Documents, reports 2019-10-08 17:07:18
Training young scientist on experimental methods for studying YAP protein and protein mechanosensor; Training young scientist on experimental advanced microscopy-AFM techniques Other 2019-09-02 14:28:37
\"Lecture notes on \"\"Role of mechanotransduction systems during stem cell differentiation\"\" and “ Advanced microscopy for protein tracking”\" Documents, reports 2019-09-02 14:28:37
Serve as a training platform providing courses, individual instruction, and consulting on STED, STORM, SIM, FCS-STED and FLIM Other 2019-09-02 14:28:37
A set of DNA-based fluorescent TF-beacons for TEAD and NF-kB inhibition; Characterization of TEAD/YAP behaviour during mammary cancer progression Documents, reports 2019-09-02 14:28:37
Curriculum of interdisciplinary studies on innovation strategies Documents, reports 2019-09-02 14:28:37
Training young scientist on the use of STED, STORM, SIM, FCS-STED and FLIM Other 2019-09-02 14:28:36
Training young scientist on experimental methods for nanobubbles and nanogels preparation; Training young scientist on experimental methods for studying the physico-chemical properties of siRNA loaded nanocarriers Other 2019-09-02 14:28:37
Support research giving access to most advanced technologies in the field of cellular imaging, data analysis and image processing available at IIT and Nikon Imaging Centre (NIC@IIT) Other 2019-09-02 14:28:36
Minute conference calls for coordination of visiting periods Documents, reports 2019-09-02 14:28:36
\"Lecture notes on \"\"Role of mechanotransduction systems during stem cell differentiation\"\"\" Other 2019-09-02 14:28:36
Training ESR on experimental methods for studying the behaviour of DNA-based conformational switching probes in solution; Training ESR on experimental methods for engineering and characterization of nanocarriers Other 2019-09-02 14:28:36
Training young scientist on biochemistry and molecular biology methods in the laboratory; Training young scientist on experimental methods for studying YAP/TEAD and NFkB Other 2019-09-02 14:28:36
Seminars held at industries and SME Other 2019-09-02 14:28:36
Definition of the best conditions to obtain and enrich iPSCs lines expressing YAP-GFP construct and its mutants; Definition of the domains of YAP protein responsible for its acknowledged mechanosensor activity Documents, reports 2019-09-02 14:28:36
Complete the synthesis and characterization of siRNA-loaded nanobubble and nanogels Documents, reports 2019-09-02 14:28:36

Take a look to the deliverables list in detail:  detailed list of NANO-SUPREMI deliverables.

 Publications

year authors and title journal last update
List of publications.
2020 Sukhvir Kaur Bhangu, Gianfranco Bocchinfuso, Muthupandian Ashokkumar, Francesca Cavalieri
Sound-driven dissipative self-assembly of aromatic biomolecules into functional nanoparticles
published pages: , ISSN: 2055-6756, DOI: 10.1039/c9nh00611g
Nanoscale Horizons 2020-03-05
2020 Rita Cimino, Elisa Grelloni, Gabriele Magna, Donato Monti, Manuela Stefanelli, Emanuela Gatto, Ernesto Placidi, Francesca Biscaglia, Marina Gobbo, Mariano Venanzi
Tuning the morphology of mesoscopic structures of porphyrin macrocycles functionalized by an antimicrobial peptide
published pages: A-I, ISSN: 1088-4246, DOI: 10.1142/s1088424619502006
Journal of Porphyrins and Phthalocyanines 2020-03-05
2019 Marta De Zotti, Gabriele Corvi, Emanuela Gatto, Benedetta Di Napoli, Claudia Mazzuca, Antonio Palleschi, Ernesto Placidi, Barbara Biondi, Marco Crisma, Fernando Formaggio, Claudio Toniolo, Mariano Venanzi
Controlling the Formation of Peptide Films: Fully Developed Helical Peptides are Required to Obtain a Homogenous Coating over a Large Area
published pages: 1688-1696, ISSN: 2192-6506, DOI: 10.1002/cplu.201900456
ChemPlusChem 84/11 2020-03-05
2019 Barbara B. Gerbelli, Sandra V. Vassiliades, Jose E. U. Rojas, Juliane N. B. D. Pelin, Rodrigo S. N. Mancini, Wallace S. G. Pereira, Andrea M. Aguilar, Mariano Venanzi, Francesca Cavalieri, Francesca Giuntini, Wendel A. Alves
Hierarchical Self‐Assembly of Peptides and its Applications in Bionanotechnology
published pages: 1900085, ISSN: 1022-1352, DOI: 10.1002/macp.201900085
Macromolecular Chemistry and Physics 220/14 2020-03-05
2018 Marta De Zotti, Beatrice Muzzi, Emanuela Gatto, Benedetta Di Napoli, Claudia Mazzuca, Antonio Palleschi, Ernesto Placidi, Fernando Formaggio, Claudio Toniolo, Mariano Venanzi
Tuning the Morphology of Nanostructured Peptide Films by the Introduction of a Secondary Structure Conformational Constraint: A Case Study of Hierarchical Self-Assembly
published pages: 6305-6313, ISSN: 1520-6106, DOI: 10.1021/acs.jpcb.8b01877
The Journal of Physical Chemistry B 122/24 2019-10-09
2018 Juliane N. B. D. Pelin, Emanuela Gatto, Mariano Venanzi, Francesca Cavalieri, Cristiano L. P. Oliveira, Herculano Martinho, Emerson R. Silva, Andrea M. Aguilar, Juliana S. Souza, Wendel A. Alves
Hybrid Conjugates Formed between Gold Nanoparticles and an Amyloidogenic Diphenylalanine-Cysteine Peptide
published pages: 6756-6765, ISSN: 2365-6549, DOI: 10.1002/slct.201801345
ChemistrySelect 3/24 2019-10-09

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