Opendata, web and dolomites

PACE

Paleogenetic extraction and analysis from challenging environments

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 PACE project word cloud

Explore the words cloud of the PACE project. It provides you a very rough idea of what is the project "PACE" about.

barrier    researcher    near    locations    training    parts    skull    last    history    decade    sampling    neanderthals    modern    preserved    benefits    difficult    human    archaic    questions    interdisciplinary    collaborators    significantly    methodological    exceptionally    lineage    continental    spurred    inherently    nature    peoples    gained    international    undergone    humans    ancient    formidable    preservation    attempts    thought    ancestors    advancements    cold    species    time    dynamics    favorable    owing    depths    impossible    histories    inquiry    genetics    paleogenetics    warm    scope    asia    shown    incorporates    extinct    arid    indicating    branches    environmental    throughput    answer    hts    extraction    east    southeast    surrounding    whereby    adna    broaden    environments    preliminary    techniques    admixture    perspectives    technologies    world    archaeology    sequencing    transfer    humid    attempt    host    bone    material    evolutionary    dna    gain    ago    events   

Project "PACE" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN 

Organization address
address: BELFIELD
city: DUBLIN
postcode: 4
website: www.ucd.ie

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Ireland [IE]
 Total cost 187˙866 €
 EC max contribution 187˙866 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-06-01   to  2018-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN IE (DUBLIN) coordinator 187˙866.00

Map

 Project objective

The field of ancient human DNA (aDNA) has rapidly undergone changes over the last decade. These changes have been spurred on through the use of high-throughput sequencing (HTS) technologies. These methodological advancements have increased our understanding of the human lineage to depths thought impossible only a short time ago. For example, aDNA research has shown how modern humans are related to our archaic ancestors, indicating significant admixture events throughout our evolutionary history with the Neanderthals and other now-extinct archaic species. However, to achieve these results, the ancient material has been exceptionally well preserved, owing to favorable, i.e. cold, environmental conditions. For many parts of the world, however, the environmental conditions remain a barrier to the extraction and analysis of aDNA. The nature of aDNA research is inherently interdisciplinary, whereby several branches of inquiry, such as archaeology or genetics, attempt to answer similar evolutionary questions from different perspectives. This proposal attempts to use advanced extraction and sampling methods for aDNA from challenging environments in order to broaden the scope of paleogenetics research. Although continental Europe has gained significantly from these advances, for other parts of the world, such as Southeast Asia and the Near East, this has been more difficult due to formidable preservation conditions. The goal of this proposal is to build on promising preliminary results that target a specific bone in the human skull in order to gain a better understanding surrounding the dynamics of aDNA preservation, while at the same time, gain insight into the evolutionary histories of peoples from warm and humid, or warm and arid, locations. Our proposal incorporates state-of-the-art HTS techniques, includes a comprehensive training program with international collaborators, and benefits from a two-way transfer of knowledge between host and researcher.

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The information about "PACE" are provided by the European Opendata Portal: CORDIS opendata.

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