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HippBoundariesPE

Identifying the building blocks of episodic memory: how the hippocampus parses boundless experience into discrete events

Total Cost €

0

EC-Contrib. €

0

Partnership

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 HippBoundariesPE project word cloud

Explore the words cloud of the HippBoundariesPE project. It provides you a very rough idea of what is the project "HippBoundariesPE" about.

subfields    ongoing    perceptual    7t    normal    illuminate    surprise    lays    occurrences    nature    continuous    received    researcher    healthy    salient    linked    applicable    pe    boundaries    theories    collaborations    designed    stream    brief    memory    laid    previously    film    combining    stimuli    fmri    segment    error    expertise    neuropsychological    induce    expectancy    forms    interpreted    employed    boundary    provides    involvement    distinction    first    hypothesize    ends    hippocampus    significantly    patients    differ    fails    few    recognition    hippocampal    significance    event    employing    explicit    interventions    units    constitutes    focal    complementary    surprising    registered    region    host    individuals    events    life    segmentation    occur    infancy    elucidate    mnemonic    lesions    prediction    episodic    clips    posit    segments    amnesic    discrete    dissociate    upcoming    ameliorating    disorders    encoding   

Project "HippBoundariesPE" data sheet

The following table provides information about the project.

Coordinator
THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE 

Organization address
address: TRINITY LANE THE OLD SCHOOLS
city: CAMBRIDGE
postcode: CB2 1TN
website: www.cam.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website https://www.mrc-cbu.cam.ac.uk/people/aya.ben-yakov/
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-08-18   to  2018-08-17

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE UK (CAMBRIDGE) coordinator 103˙563.00
2    MEDICAL RESEARCH COUNCIL UK (SWINDON) participant 79˙891.00

Map

 Project objective

Life provides us with a continuous stream of information that ends up being organized in long-term memory as distinct events. How does this occur? Leading theories posit that surprising occurrences (when prediction of the immediate future fails) are interpreted by the system as event boundaries that segment ongoing experience. Will any type of surprise induce such segmentation? Moreover, how are these segments then laid down in memory as discrete units? The proposed research addresses these key issues in a two phase study, combining fMRI of healthy individuals with a neuropsychological study of amnesic patients, and using tailored film clips designed to dissociate between distinct forms of prediction error (PE) – low-level PE (salient perceptual changes) and high-level PE (explicit expectancy of an upcoming change). We hypothesize that the key region in this process may be the hippocampus, a region strongly linked to formation of episodic memory. Combining a 7T fMRI study (enabling distinction between hippocampal subfields) with a study of patients with focal hippocampal lesions will enable us to elucidate the nature and necessity of hippocampal involvement in segmentation. The significance of this study lays first in its potential to illuminate how real-life events are registered to memory, a process which is likely to differ significantly from the encoding of brief, simple stimuli that have been employed previously. The importance of studying encoding of complex events has recently received increasing recognition, yet this is still only at its infancy, with very few studies employing this approach. Combining the complementary expertise of the researcher and the host, the proposed research aims to identify what constitutes an event boundary in mnemonic processing. Through future collaborations, this has the potential to lead to applicable interventions for improving normal memory and ameliorating mnemonic disorders.

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