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ARMOURY

Arthroscopic Regenerative Medicine for Early-Stage Treatment of OA

Total Cost €

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EC-Contrib. €

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Partnership

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Project "ARMOURY" data sheet

The following table provides information about the project.

Coordinator
JRI ORTHOPAEDICS LIMITED 

Organization address
address: 18 CHURCHILL WAY 35 A BUSINESS PARK
city: SHEFFIELD
postcode: S35 2PY
website: www.jri-ltd.co.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website http://jri-ltd.com/
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2016
 Duration (year-month-day) from 2016-08-01   to  2017-01-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    JRI ORTHOPAEDICS LIMITED UK (SHEFFIELD) coordinator 50˙000.00

Map

 Project objective

Osteoarthritis (OA) affects about 10% of the global population. It has a major impact on a patient’s quality of life; with pain and physical function being worse than chronic obstructive pulmonary disease or even cardiovascular disease. Its prevalence is increasing, by 2020 it will be the 4th leading cause of disability. OA is caused by ‘wear and tear’ and currently only symptoms are treated using pain killers until major surgery is needed, then the joint is replaced. Although joint replacements have improved and often last over 30 years, they do fail with about 10% of all joint replacement operations being to fix a failed implant. In this project JRI is working with University Medical Center Utrecht (UMCU), The Netherlands and the Cell and Gene Therapy Catapult (CGT), UK, to develop a new treatment of OA in the hip and take it to market. This involves catching the disease early when it appears as a distinct lesion. JRI has developed Hummingbird, a system that can get into the complex anatomy of the hip and precisely cut out patches of diseased tissue. Then treating these patches with a cell-based treatment developed by UMCU and successfully used to treat OA in the knee. JRI believes that this treatment can be provided at a competitive price and at a scale to meet the global market. However, to do this they will need to build a robust business case and define in detail the regulatory pathways to the markets in Europe and USA. They will do this by working with CGT. This Feasibility Study is the first phase of this work. With CGT, JRI will define: the regulatory pathway, the cost of providing the treatment, the reimbursement methods and the likely market share. The second phase will be in the first-in-human study and a critical step in both meeting the regulations and defining the benefits to this cell-based treatment being applied to the hip. This treatment may not cure OA, but should delay major joint surgery and, in time, may allow some to avoid it all together.

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The information about "ARMOURY" are provided by the European Opendata Portal: CORDIS opendata.

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