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VIRUSCAN SIGNED

Optomechanics for Virology

Total Cost €

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EC-Contrib. €

0

Partnership

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 VIRUSCAN project word cloud

Explore the words cloud of the VIRUSCAN project. It provides you a very rough idea of what is the project "VIRUSCAN" about.

tackle    stiffness    spread    adjustments    frontier    viral    clinical    stages    quantum    blood    mechanical    native    nanoscale    characterization    platform    personalized    delivered    pathogen    west    screening    infections    ones    diagnosis    ground    situations    gold    protocols    lately    nanoelectromechanical    quick    interdisciplinary    acid    demonstrated    transfusions    cycle    discern    consuming    safety    nanoelectromechanics    rapid    infectivity    africa    viruses    demands    biophysics    reducing    optomechanics    mass    wave    cheaper    time    brazil    diagnostic    physics    antibiotics    constraints    mutations    physical    infectious    gravitational    life    advancements    levels    create    asses    treatment    applicability    ebola    served    zika    trustworthy    viruscan    overcome    standard    regulator    fundamental    biosensing    disentangled    parallel    patients    pathogens    particles    nucleic    identification    detection    full    adsorbates    technologies    virus    infective    spectrometry    latent    emergency    intrinsic    act    community   

Project "VIRUSCAN" data sheet

The following table provides information about the project.

Coordinator
AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS 

Organization address
address: CALLE SERRANO 117
city: MADRID
postcode: 28006
website: http://www.csic.es

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website https://viruscanproject.eu/
 Total cost 7˙148˙586 €
 EC max contribution 7˙148˙586 € (100%)
 Programme 1. H2020-EU.1.2.2. (FET Proactive)
 Code Call FETPROACT-2016
 Funding Scheme RIA
 Starting year 2016
 Duration (year-month-day) from 2016-11-01   to  2021-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS ES (MADRID) coordinator 1˙248˙082.00
2    COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES FR (PARIS 15) participant 1˙098˙870.00
3    NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO NL (DEN HAAG) participant 1˙079˙262.00
4    HEINRICH-PETTE INSTITUT LEIBNIZ INSTITUT FUER EXPERIMENTELLE VIROLOGIE DE (HAMBURG) participant 882˙500.00
5    UNIVERSITE DE PARIS FR (PARIS) participant 856˙486.00
6    FASMATECH EPISTIMONIKI KAI TECHNOLOGIKI ANONYMI ETAIREIA EL (AFIDNES ATTIKIS) participant 800˙572.00
7    SERVICIO MADRILENO DE SALUD ES (MADRID) participant 603˙750.00
8    RIJKSUNIVERSITEIT GRONINGEN NL (GRONINGEN) participant 579˙062.00
9    UNIVERSITE PARIS DIDEROT - PARIS 7 FR (PARIS) participant 0.00

Map

 Project objective

Viral infections diagnosis demands novel, cheaper and rapid technologies to overcome present constraints. Current gold standard for diagnosis of viral infections is based on pathogen-targeted nucleic acid identification; thus, it cannot discern infectious stages from latent ones and it demands time consuming adjustments when mutations occur or new emerging viruses are to be included in the diagnostic protocols. Lately, optomechanics has served to fundamental advancements in physics, from gravitational wave detection to the study of mechanical quantum ground states but it has not yet delivered its full applicability potential. VIRUSCAN aims to apply frontier advancements in optomechanics to the biosensing and diagnostic fields and to create a new interdisciplinary research community with the goal to advance optomechanics, nanoelectromechanics, native mass spectrometry and biophysics towards clinical applications. VIRUSCAN will provide a novel technology capable to identify viral particles and asses their infective potential through the characterization of two physical parameters: mass and stiffness. Stiffness of viral particles has been recently known to act as a regulator of their infectivity at different stages of the virus life cycle. In parallel, advancements in nanoelectromechanical systems have recently demonstrated that stiffness and mass information from nanoscale adsorbates can be disentangled. Targeting intrinsic physical properties of viral particles will allow developing an open platform that will tackle any virus and their mutations. VIRUSCAN will have impact at all levels by: providing a personalized treatment to the patients, reducing the use of not effective antibiotics, increasing safety in blood transfusions, allowing a quick and trustworthy response to emergency situations (e.g. recent EBOLA in West Africa and the ZIKA in Brazil), reducing the spread of viral infections, reducing costs per analysis and screening of a wide range of pathogens.

 Publications

year authors and title journal last update
List of publications.
2017 Valerio Pini, Daniel Ramos, Carmen M. Dominguez, Jose Jaime Ruz, Oscar Malvar, Priscila M. Kosaka, Zachary J. Davis, Javier Tamayo, Montserrat Calleja
Optimization of the readout of microdrum optomechanical resonators
published pages: 37-41, ISSN: 0167-9317, DOI: 10.1016/j.mee.2017.10.008
Microelectronic Engineering 183-184 2020-02-19
2018 Ronja Pogan, Carola Schneider, Rudolph Reimer, Grant Hansman, Charlotte Uetrecht
Norovirus-like VP1 particles exhibit isolate dependent stability profiles
published pages: 64006, ISSN: 0953-8984, DOI: 10.1088/1361-648x/aaa43b
Journal of Physics: Condensed Matter 30/6 2020-02-19
2017 Carmen M. Domínguez, Daniel Ramos, Jesús Mingorance, José L. G. Fierro, Javier Tamayo, Montserrat Calleja
Direct Detection of OXA-48 Carbapenemase Gene in Lysate Samples through Changes in Mechanical Properties of DNA Monolayers upon Hybridization
published pages: 968-973, ISSN: 0003-2700, DOI: 10.1021/acs.analchem.7b04094
Analytical Chemistry 90/1 2020-02-19
2018 J. J. Ruz, V. Pini, O. Malvar, P. M. Kosaka, M. Calleja, J. Tamayo
Effect of surface stress induced curvature on the eigenfrequencies of microcantilever plates
published pages: 105213, ISSN: 2158-3226, DOI: 10.1063/1.5053561
AIP Advances 8/10 2020-02-19
2018 Eloise Pariset, Charlotte Parent, Yves Fouillet, Boizot François, Nicolas Verplanck, Frédéric Revol-Cavalier, Aurélie Thuaire, Vincent Agache
Separation of Biological Particles in a Modular Platform of Cascaded Deterministic Lateral Displacement Modules
published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-34958-8
Scientific Reports 8/1 2020-02-19
2018 Joanna Luczkowiak, Fatima Lasala, Marta Mora-Rillo, Jose R Arribas, Rafael Delgado
Broad Neutralizing Activity Against Ebolaviruses Lacking the Mucin-Like Domain in Convalescent Plasma Specimens From Patients With Ebola Virus Disease
published pages: S574-S581, ISSN: 0022-1899, DOI: 10.1093/infdis/jiy302
The Journal of Infectious Diseases 218/suppl_5 2020-02-19
2018 Eloise Pariset, Catherine Pudda, François Boizot, Nicolas Verplanck, Frédéric Revol-Cavalier, Jean Berthier, Aurélie Thuaire, Vincent Agache
Purification of complex samples: Implementation of a modular and reconfigurable droplet-based microfluidic platform with cascaded deterministic lateral displacement separation modules
published pages: e0197629, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0197629
PLOS ONE 13/5 2020-02-19
2018 Ronja Pogan, Jasmin Dülfer, Charlotte Uetrecht
Norovirus assembly and stability
published pages: 59-65, ISSN: 1879-6257, DOI: 10.1016/j.coviro.2018.05.003
Current Opinion in Virology 31 2020-02-19
2017 Priscila M. Kosaka, Montserrat Calleja, Javier Tamayo
Optomechanical devices for deep plasma cancer proteomics
published pages: , ISSN: 1044-579X, DOI: 10.1016/j.semcancer.2017.08.011
Seminars in Cancer Biology 2020-02-19

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