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VIRUSCAN SIGNED

Optomechanics for Virology

Total Cost €

0

EC-Contrib. €

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Partnership

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Outcomes and
results

VIRUSCAN project word cloud

Explore the words cloud of the VIRUSCAN project. It provides you a very rough idea of what is the project "VIRUSCAN" about.

disentangled latent safety technologies infectivity interdisciplinary antibiotics nucleic standard mass served nanoelectromechanics physics frontier tackle screening ground consuming diagnostic zika discern mechanical spectrometry characterization delivered viruses overcome acid lately regulator intrinsic reducing time create applicability virus adjustments infections nanoelectromechanical particles situations gravitational spread africa biosensing quick west act physical platform brazil native pathogen infective viruscan levels wave optomechanics viral demonstrated gold blood life constraints asses patients full diagnosis ones community trustworthy demands protocols cycle biophysics adsorbates quantum personalized stiffness treatment rapid infectious mutations parallel nanoscale identification pathogens cheaper clinical ebola fundamental detection emergency advancements stages transfusions

Project "VIRUSCAN" data sheet

The following table provides information about the project.

Coordinator	AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS Organization address address: CALLE SERRANO 117 city: MADRID postcode: 28006 website: http://www.csic.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Spain [ES]
Project website	https://viruscanproject.eu/
Total cost	7˙148˙586 €
EC max contribution	7˙148˙586 € (100%)
Programme	1. H2020-EU.1.2.2. (FET Proactive)
Code Call	FETPROACT-2016
Funding Scheme	RIA
Starting year	2016
Duration (year-month-day)	from 2016-11-01 to 2021-10-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS Organization address address: CALLE SERRANO 117 city: MADRID postcode: 28006 website: http://www.csic.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (MADRID)	coordinator	1˙248˙082.00
2	COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES Organization address address: RUE LEBLANC 25 city: PARIS 15 postcode: 75015 website: www.cea.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS 15)	participant	1˙098˙870.00
3	NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO Organization address address: ANNA VAN BUERENPLEIN 1 city: DEN HAAG postcode: 2595 DA website: www.tno.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (DEN HAAG)	participant	1˙079˙262.00
4	HEINRICH-PETTE INSTITUT LEIBNIZ INSTITUT FUER EXPERIMENTELLE VIROLOGIE HEINRICH-PETTE INSTITUT LEIBNIZ INSTITUT FUER EXPERIMENTELLE VIROLOGIE Organization address address: MARTINISTRASSE 52 city: HAMBURG postcode: 20251 website: www.hpi-hamburg.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (HAMBURG)	participant	882˙500.00
5	UNIVERSITE DE PARIS UNIVERSITE DE PARIS Organization address address: 85 BD SAINT GERMAIN city: PARIS postcode: 75006 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	856˙486.00
6	FASMATECH EPISTIMONIKI KAI TECHNOLOGIKI ANONYMI ETAIREIA FASMATECH EPISTIMONIKI KAI TECHNOLOGIKI ANONYMI ETAIREIA Organization address address: 28TH KLM ATHINA LAMIA NATIONAL ROAD city: AFIDNES ATTIKIS postcode: 19014 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (AFIDNES ATTIKIS)	participant	800˙572.00
7	SERVICIO MADRILENO DE SALUD SERVICIO MADRILENO DE SALUD Organization address address: PLAZA CARLOS TRIAS BERTRAN 7 city: MADRID postcode: 28020 website: http://cort.as/10Yf contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (MADRID)	participant	603˙750.00
8	RIJKSUNIVERSITEIT GRONINGEN RIJKSUNIVERSITEIT GRONINGEN Organization address address: Broerstraat 5 city: GRONINGEN postcode: 9712CP website: www.rug.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (GRONINGEN)	participant	579˙062.00
9	UNIVERSITE PARIS DIDEROT - PARIS 7 UNIVERSITE PARIS DIDEROT - PARIS 7 Organization address address: RUE THOMAS MANN 5 city: PARIS postcode: 75205 website: www.univ-paris-diderot.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	0.00

Map

Project objective

Viral infections diagnosis demands novel, cheaper and rapid technologies to overcome present constraints. Current gold standard for diagnosis of viral infections is based on pathogen-targeted nucleic acid identification; thus, it cannot discern infectious stages from latent ones and it demands time consuming adjustments when mutations occur or new emerging viruses are to be included in the diagnostic protocols. Lately, optomechanics has served to fundamental advancements in physics, from gravitational wave detection to the study of mechanical quantum ground states but it has not yet delivered its full applicability potential. VIRUSCAN aims to apply frontier advancements in optomechanics to the biosensing and diagnostic fields and to create a new interdisciplinary research community with the goal to advance optomechanics, nanoelectromechanics, native mass spectrometry and biophysics towards clinical applications. VIRUSCAN will provide a novel technology capable to identify viral particles and asses their infective potential through the characterization of two physical parameters: mass and stiffness. Stiffness of viral particles has been recently known to act as a regulator of their infectivity at different stages of the virus life cycle. In parallel, advancements in nanoelectromechanical systems have recently demonstrated that stiffness and mass information from nanoscale adsorbates can be disentangled. Targeting intrinsic physical properties of viral particles will allow developing an open platform that will tackle any virus and their mutations. VIRUSCAN will have impact at all levels by: providing a personalized treatment to the patients, reducing the use of not effective antibiotics, increasing safety in blood transfusions, allowing a quick and trustworthy response to emergency situations (e.g. recent EBOLA in West Africa and the ZIKA in Brazil), reducing the spread of viral infections, reducing costs per analysis and screening of a wide range of pathogens.

Publications

List of publications.
year	authors and title	journal	last update
2017	Valerio Pini, Daniel Ramos, Carmen M. Dominguez, Jose Jaime Ruz, Oscar Malvar, Priscila M. Kosaka, Zachary J. Davis, Javier Tamayo, Montserrat Calleja Optimization of the readout of microdrum optomechanical resonators published pages: 37-41, ISSN: 0167-9317, DOI: 10.1016/j.mee.2017.10.008	Microelectronic Engineering 183-184	2020-02-19
2018	Ronja Pogan, Carola Schneider, Rudolph Reimer, Grant Hansman, Charlotte Uetrecht Norovirus-like VP1 particles exhibit isolate dependent stability profiles published pages: 64006, ISSN: 0953-8984, DOI: 10.1088/1361-648x/aaa43b	Journal of Physics: Condensed Matter 30/6	2020-02-19
2017	Carmen M. DomÃnguez, Daniel Ramos, JesÃºs Mingorance, JosÃ© L. G. Fierro, Javier Tamayo, Montserrat Calleja Direct Detection of OXA-48 Carbapenemase Gene in Lysate Samples through Changes in Mechanical Properties of DNA Monolayers upon Hybridization published pages: 968-973, ISSN: 0003-2700, DOI: 10.1021/acs.analchem.7b04094	Analytical Chemistry 90/1	2020-02-19
2018	J. J. Ruz, V. Pini, O. Malvar, P. M. Kosaka, M. Calleja, J. Tamayo Effect of surface stress induced curvature on the eigenfrequencies of microcantilever plates published pages: 105213, ISSN: 2158-3226, DOI: 10.1063/1.5053561	AIP Advances 8/10	2020-02-19
2018	Eloise Pariset, Charlotte Parent, Yves Fouillet, Boizot FranÃ§ois, Nicolas Verplanck, FrÃ©dÃ©ric Revol-Cavalier, AurÃ©lie Thuaire, Vincent Agache Separation of Biological Particles in a Modular Platform of Cascaded Deterministic Lateral Displacement Modules published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-34958-8	Scientific Reports 8/1	2020-02-19
2018	Joanna Luczkowiak, Fatima Lasala, Marta Mora-Rillo, Jose R Arribas, Rafael Delgado Broad Neutralizing Activity Against Ebolaviruses Lacking the Mucin-Like Domain in Convalescent Plasma Specimens From Patients With Ebola Virus Disease published pages: S574-S581, ISSN: 0022-1899, DOI: 10.1093/infdis/jiy302	The Journal of Infectious Diseases 218/suppl_5	2020-02-19
2018	Eloise Pariset, Catherine Pudda, FranÃ§ois Boizot, Nicolas Verplanck, FrÃ©dÃ©ric Revol-Cavalier, Jean Berthier, AurÃ©lie Thuaire, Vincent Agache Purification of complex samples: Implementation of a modular and reconfigurable droplet-based microfluidic platform with cascaded deterministic lateral displacement separation modules published pages: e0197629, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0197629	PLOS ONE 13/5	2020-02-19
2018	Ronja Pogan, Jasmin DÃ¼lfer, Charlotte Uetrecht Norovirus assembly and stability published pages: 59-65, ISSN: 1879-6257, DOI: 10.1016/j.coviro.2018.05.003	Current Opinion in Virology 31	2020-02-19
2017	Priscila M. Kosaka, Montserrat Calleja, Javier Tamayo Optomechanical devices for deep plasma cancer proteomics published pages: , ISSN: 1044-579X, DOI: 10.1016/j.semcancer.2017.08.011	Seminars in Cancer Biology	2020-02-19

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