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HypoSens SIGNED

Nano-confined photonic system for detection of breast cancer spread to the lymph nodes

Total Cost €

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EC-Contrib. €

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Partnership

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 HypoSens project word cloud

Explore the words cloud of the HypoSens project. It provides you a very rough idea of what is the project "HypoSens" about.

renal    economic    life    diagnosis    million    sentinel    wavefront    women    cells    nodes    vulval    hospitals    media    metastatic    personalised    infrared    validation    correlates    tumour    patients    industrial    burden    hyposens    shaping    nano    device    decide    sensors    worldwide    affordable    antibody    clinical    solution    stages    options    concentration    staging    lymph    porphyrin    functionalised    accurate    vision    node    initial    moiety    optical    tool    collected    breast    alternative    oxygen    approximate    prognosis    scattering    oncologists    diagnostics    particles    invasive    demonstration    containing    quality    procedure    societal    surgical    imaging    enabled    prognostic    strategically    temperature    near    data    clinicians    metastasis    specially    later    treatment    register    progression    bad    cancer    body    local    signals    expectancy    tumor    designed    therapy    gastric    biopsy    involvement    injected    additional    patient    consist    colorectal    fast    breakthrough    prompt    markets    accepted   

Project "HypoSens" data sheet

The following table provides information about the project.

Coordinator
ACONDICIONAMIENTO TARRASENSE ASSOCIACION 

Organization address
address: CARRER DE LA INNOVACIO 2
city: TERRASSA
postcode: 8225
website: www.leitat.org

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website http://hyposens.eu/
 Total cost 3˙998˙646 €
 EC max contribution 3˙998˙646 € (100%)
 Programme 1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT))
 Code Call H2020-ICT-2016-1
 Funding Scheme RIA
 Starting year 2016
 Duration (year-month-day) from 2016-11-01   to  2019-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ACONDICIONAMIENTO TARRASENSE ASSOCIACION ES (TERRASSA) coordinator 672˙083.00
2    TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY IL (HAIFA) participant 539˙041.00
3    MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV DE (MUENCHEN) participant 490˙981.00
4    FUNDACION RIOJA SALUD-FRS ES (LOGRONO) participant 407˙677.00
5    SOFIA UNIVERSITY ST KLIMENT OHRIDSKI BG (SOFIA) participant 403˙162.00
6    BCB Informatica y Control S.L. ES (Madrid) participant 372˙500.00
7    OBELIS SA BE (BRUXELLES) participant 319˙200.00
8    FUNDACION PARA EL DESARROLLO Y LA INNOVACION TECNOLOGICA ES (MADRID) participant 276˙449.00
9    KNOWLEDGE INNOVATION MARKET S.L. ES (BARCELONA) participant 240˙250.00
10    UFO AL (TIRANA) participant 193˙750.00
11    TECNOLOGIAS AVANZADAS INSPIRALIA SL ES (LOGRONO) participant 83˙551.00

Map

 Project objective

The Vision of HypoSens is to develop a widely accepted,non-invasive and crucial prognostic tool for breast cancer progression in early stages to help clinicians and specially oncologists to decide about prompt therapy approaches to patients and improve quality of life and expectancy. Our breakthrough research will focus on the development, pre-clinical and clinical validation, and industrial demonstration of a unique all optical cancer prognostic system that will determine presence of cancer cells in the breast lymph nodes and characterize them, which correlates with presence of metastasis and bad prognosis. HypoSens prognostic system will consist of a non-invasive Near-infrared imaging device able to register signals through scattering media enabled by the implementation of wavefront shaping,that will process data collected by injected tumour-targeted body antibody functionalised nano-particles containing porphyrin sensors that will determine local oxygen concentration and local temperature distribution in the cancer cells.The HypoSens imaging system is strategically designed to offer a non-invasive alternative to the Sentinel Lymph Node Biopsy,the current surgical procedure for breast cancer staging. With an approximate cost of 60,000€ per device unit and additional 5,000€ per patient, the device is an affordable, accurate, easy to use prognostic solution for clinicians towards more accurate and fast diagnostics and personalised treatment options.The initial target of the project is metastatic breast cancer, with potential later involvement in other cancer markets, e.g. vulval, renal, colorectal, gastric etc (via the use of different tumor-targeting moiety).With an estimated 1.7 million new cases each year, breast cancer is the most common cancer among women worldwide.Its low cost will enable a wide and fast take-up by clinicians and hospitals leading to an important reduction of the economic and societal burden related to the diagnosis and treatment of cancer.

 Deliverables

List of deliverables.
Project video Websites, patent fillings, videos etc. 2020-03-11 14:36:19
Dissemination Kit Documents, reports 2020-03-11 14:36:22
Obtaining review board approval Documents, reports 2020-03-11 14:36:15
Market Analysis Documents, reports 2019-11-18 11:23:42
Project website with content for public consumption Websites, patent fillings, videos etc. 2019-11-18 11:23:42

Take a look to the deliverables list in detail:  detailed list of HypoSens deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 E. Heinrich, Yu. Avlasevich, S. Baluschev, K. Landfester
Mixed benzo- naphthoporphyrins for broadband-excited photon energy annihilation upconversion
published pages: , ISSN: , DOI:
20th European Symposium on Organic Chemistry 2019-12-17
2019 Nadzeya Nazarova, Yuri Avlasevich, Katharina Landfester, Stanislav Baluschev
All‐Optical Temperature Sensing in Organogel Matrices via Annihilation Upconversion
published pages: 1020-1026, ISSN: 2367-0932, DOI: 10.1002/cptc.201900093
ChemPhotoChem 3/10 2019-11-22
2018 N. V. Nazarova, Yu. S. Avlasevich, K. Landfester, S. Baluschev
Stimuli-responsive protection of optically excited triplet ensembles against deactivation by molecular oxygen
published pages: , ISSN: 1477-9226, DOI: 10.1039/c7dt03698a
Dalton Transactions 2019-11-18
2018 Ernesta Heinrich, Yuri Avlasevich, Katharina Landfester, Stanislav Baluschev
Annihilation upconversion: harvesting the entire deep-red spectral range of the sun irradiation
published pages: 1, ISSN: 1947-7988, DOI: 10.1117/1.JPE.8.022002
Journal of Photonics for Energy 8/02 2019-11-18
2019 Kartheek Katta, Dmitry Busko, Yuri Avlasevich, Katharina Landfester, Stanislav Baluschev, Rafael Muñoz-Espí
Ceria/polymer nanocontainers for high-performance encapsulation of fluorophores
published pages: 522-530, ISSN: 2190-4286, DOI: 10.3762/bjnano.10.53
Beilstein Journal of Nanotechnology 10 2019-11-18
2018 Kartheek Katta, Dmitry Busko, Katharina Landfester, Stanislav Baluschev, Rafael Muñoz-Espí
Inorganic Protection of Polymer Nanocapsules: A Strategy to Improve the Efficiency of Encapsulated Optically Active Molecules
published pages: 1356-1362, ISSN: 0021-2148, DOI: 10.1002/ijch.201800111
Israel Journal of Chemistry 58/12 2019-11-18

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The information about "HYPOSENS" are provided by the European Opendata Portal: CORDIS opendata.

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