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NOC

Nerve-on-Chips

Total Cost €

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EC-Contrib. €

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Partnership

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 NOC project word cloud

Explore the words cloud of the NOC project. It provides you a very rough idea of what is the project "NOC" about.

2014    tissues    2d    ultimately    founded       organoids    market    health    2020    vitro    purchase    animal    simulate    noc    organ    expectancy    neuron    total    dimensional    licenses    assessing    patients    absence    worldwide    devastating    turnover    share    improvement    solutions    turn    financial    validating    ip    disease    clients    tri    human    time    competitiveness    biotech    care    3d    million    networks    physiological    15    ooc    memories    technological    individual    reduce    compatibility    chips    patented    diseases    lives    suffer    function    incidence    trillion    microbrain    individuals    nerve    models    few    65    alzheimer    culture    grow    microfluidic    economic    mbbt    chain    worth    clinical    biological    drugs    shape    readouts    startup    efficiency    reconstructed    agencies    nd    supply    competitors    visualization    coming    biopharmaceutical    provides    conventional    burden       people    society    patent    innovative    life    generate    predicting    reconstitution    advantages    subunits    subcategory    lose    types    feasibility    micron    neurodegenerative    drug    independence    prevent    biology    latter    cureor    relatives    policy    start    functions   

Project "NOC" data sheet

The following table provides information about the project.

Coordinator
MICROBRAIN BIOTECH 

Organization address
address: 46 RUE CARDINET
city: PARIS
postcode: 75017
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Project website http://microbrainbiotech.com/
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2016
 Duration (year-month-day) from 2016-12-01   to  2017-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    MICROBRAIN BIOTECH FR (PARIS) coordinator 50˙000.00

Map

 Project objective

Neurodegenerative diseases (“ND”) are devastating as they cause individuals to lose their memories, independence, and ultimately, their lives. In the absence of drugs able to cureor prevent start of ND, the latter are a human and financial burden for individual patients, their relativesthe health care system and society in general. The worldwide economic impact of ND is evaluated at $2 trillion a year. The incidence of ND is expected to grow in the coming few years as life expectancy increases. In 2020, over 65 million people will suffer from Alzheimer Disease worldwide (over 6.5 million in the EU).

MicroBrain Biotech is an innovative biotech startup founded in 2014. MBBT aims at offering “turn-key solutions” to biopharmaceutical research which will take the shape of microfluidic chips offering different types of reconstructed neuron networks at the micron scale. These chips are called Nerve-on-Chips (“NoC”, subcategory of Organ-on-Chips), and they simulate the function of tissues and organ subunits. Our patented NOC technology provides many advantages over other in vitro models such as conventional two-dimensional (2D) and tri-dimensional (3D) culture systems, over organoids, and over animal models: - Reduce biopharmaceutical R&D costs and increased efficiency in clinical research (improved competitiveness) - Reduce animal testing - Predicting human-relevant drug responses - Compatibility with readouts used in biology & real time visualization - Reconstitution of complex organ-level physiological functions

NOC will allow to reduce drug R&D costs by 15% which will generate a total turnover worth €30 million. MBBT’s objective is to reach a €2 million worth turnover (i.e.: 8% OOC market share) within the 3 next years. The feasibility study will allow us to ensure IP policy (improvement patent, purchase of licenses) while assessing the market (supply chain, drug agencies, competitors, clients…) and validating the technological and biological approach.

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The information about "NOC" are provided by the European Opendata Portal: CORDIS opendata.

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