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M-CUBE SIGNED

MetaMaterials antenna for ultra-high field MRI

Total Cost €

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EC-Contrib. €

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Partnership

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 M-CUBE project word cloud

Explore the words cloud of the M-CUBE project. It provides you a very rough idea of what is the project "M-CUBE" about.

barriers    antenna    changing    eight    optical    consists    solutions    index    idea    scanners    limits    smes    manmade    rate    leaders    imaging    industrial    expectations    metamaterial       active    frequency    personalized    solution    composite    spatial    volunteers    expensive    preclinical    radio    innovative    electromagnetic    physicists    disease    absorption    clinical    disruptive    tailor    earlier    mri    context    radically    sar    centered    antennas    resonance    human    metamaterials    limited    medicine    magnetic    passive    physicians    resolutions    negative    temporal    actors    accurate    designed    cube    detect    closely    relies    materials    ultra    structured    validated    scientifically    interdisciplinary    pave    structures    nature    healthy    waves    medical    homogeneity    multiple    doctors    breakthrough    tests    academic    detection    coil    universities    guarantee    diagnosis    diseases    paradigm    diagnostically    drastically    technological    body    tackle    patient    unavailable    rf    lack   

Project "M-CUBE" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITE D'AIX MARSEILLE 

Organization address
address: Boulevard Charles Livon 58
city: Marseille
postcode: 13284
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Project website http://www.mcube-project.eu/
 Total cost 4˙582˙346 €
 EC max contribution 3˙945˙346 € (86%)
 Programme 1. H2020-EU.1.2.1. (FET Open)
 Code Call H2020-FETOPEN-1-2016-2017
 Funding Scheme RIA
 Starting year 2017
 Duration (year-month-day) from 2017-01-01   to  2020-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITE D'AIX MARSEILLE FR (Marseille) coordinator 1˙230˙023.00
2    COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES FR (PARIS 15) participant 705˙256.00
3    UNIVERSITAIR MEDISCH CENTRUM UTRECHT NL (UTRECHT) participant 468˙778.00
4    UNIVERSITE CATHOLIQUE DE LOUVAIN BE (LOUVAIN LA NEUVE) participant 318˙941.00
5    AALTO KORKEAKOULUSAATIO SR FI (ESPOO) participant 313˙125.00
6    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) participant 312˙250.00
7    MULTIWAVE TECHNOLOGIES AG CH (GENEVA) participant 250˙625.00
8    MR COILS BV NL (ZALTBOMMEL) participant 233˙846.00
9    TESLA DYNAMIC COILS BV NL (ZALTBOMMEL) participant 112˙500.00
10    ITMO UNIVERSITY RU (ST PETERSBURG) participant 0.00
11    THE AUSTRALIAN NATIONAL UNIVERSITY AU (CANBERRA) participant 0.00

Map

 Project objective

M-Cube aims at changing the paradigm of High-Field MRI and Ultra High-Field antennas to offer a much better insight on the human body and enable earlier detection of diseases. Our main objective is to go beyond the limits of MRI clinical imaging and radically improve spatial and temporal resolutions. The clinical use of High-field MRI scanners is drastically limited due to the lack of homogeneity and to the Specific Absorption Rate (SAR) of the Radio Frequency (RF) fields associated with the magnetic resonance. The major way to tackle and solve these problems consists in increasing the number of active RF antennas, leading to complex and expensive solutions. M-Cube solution relies on innovative systems based upon passive metamaterial structures to avoid multiple active elements. These systems are expected to make High-Field MRI fully diagnostically relevant for physicians. To achieve these expectations, M-Cube consortium will develop a disruptive metamaterial antenna technology. This we will able us to tackle both the lack of homogeneity and SAR barriers. Metamaterials are composite structured manmade materials designed to produce effective properties unavailable in nature (e.g. negative optical index). They allow us to tailor electromagnetic waves at will. Thus, the scientifically ambitious idea is to develop antennas based on this unique ability for whole body coil. This technological breakthrough will be validated by preclinical and clinical tests with healthy volunteers. M-Cube gathers an interdisciplinary consortium composed of academic leaders in the field, eight universities, and two promising SMEs. Physicists, medical doctors and industrial actors will work closely all along the implementation of the project to guarantee the success this novel approach, a “patient-centered” solution which will pave the way for a more accurate diagnosis in the context of personalized medicine and will enable to detect a disease much earlier that is currently possible.

 Deliverables

List of deliverables.
First designs of potential RF coil systems with metamaterials from WP3-5 Documents, reports 2020-03-25 16:29:32
Interim Plan for Dissemination and exploiting project results Documents, reports 2020-03-25 16:29:32
CAD-models of metasurface samples and metasurface-based RF devices Other 2020-03-25 16:29:32
Description of a newly developed software analysis tool, and a report describing quantitatively the effect of pre-selected metamaterials on MRI fields Documents, reports 2020-03-25 16:29:32
Comparative study of metasurfaces stressed on MRI applications Documents, reports 2020-03-25 16:29:33
Version of M-Cube Website online and Communication materials Documents, reports 2020-03-25 16:29:32
Data Management Plan Open Research Data Pilot 2020-03-25 16:29:32
Definition of the metrics and the fundamental survey on hybridized antenna Documents, reports 2020-03-25 16:29:33
First MRI experiments with RF coil systems from D5.2 have been performed Documents, reports 2020-03-25 16:29:32
Realization of first designs from D6.1 with the required system hardware, phantoms, and test procedure Documents, reports 2020-03-25 16:29:32
Risk study report related to every coil prototypes before submission to national ethical authorities. This deliverable will include k-factor or q-matrices calculations Documents, reports 2020-03-25 16:29:33
Report on 3 or 4 different types of metamaterials and the possible advantages that they could bring to whole-body MRI diagnosis. Ranking among those metamaterials Documents, reports 2020-03-25 16:29:32

Take a look to the deliverables list in detail:  detailed list of M-CUBE deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Marine A. C. Moussu, Luisa Ciobanu, Sergej Kurdjumov, Elizaveta Nenasheva, Boucif Djemai, Marc Dubois, Andrew G. Webb, Stefan Enoch, Pavel Belov, Redha Abdeddaim, Stanislav Glybovski
Systematic Analysis of the Improvements in Magnetic Resonance Microscopy with Ferroelectric Composite Ceramics
published pages: 1900912, ISSN: 0935-9648, DOI: 10.1002/adma.201900912
Advanced Materials 2020-03-25
2019 Kaizad Rustomji, Marc Dubois, Boris Kuhlmey, C. Martijn de Sterke, Stefan Enoch, Redha Abdeddaim, Jérôme Wenger
Direct Imaging of the Energy-Transfer Enhancement between Two Dipoles in a Photonic Cavity
published pages: , ISSN: 2160-3308, DOI: 10.1103/PhysRevX.9.011041
Physical Review X 9/1 2020-03-25
2019 Tania S. Vergara Gomez, Marc Dubois, Stanislav Glybovski, Benoit Larrat, Julien Rosny, Carsten Rockstuhl, Monique Bernard, Redha Abdeddaim, Stefan Enoch, Frank Kober
Wireless coils based on resonant and nonresonant coupled‐wire structure for small animal multinuclear imaging
published pages: e4079, ISSN: 0952-3480, DOI: 10.1002/nbm.4079
NMR in Biomedicine 32/5 2020-03-25
2019 Masoud Sharifian Mazraeh Mollaei, Sergei Alexandrovich Kurdjumov, Anna Aleksandrovna Hurshkainen, Constantin Rufovich Simovski
DECOUPLING OF TWO CLOSELY LOCATED DIPOLES BY A SINGLE PASSIVE SCATTERER FOR ULTRA-HIGH FIELD MRI
published pages: 155-166, ISSN: 1559-8985, DOI: 10.2528/PIER18101703
Progress In Electromagnetics Research 164 2020-03-25
2017 Sergei Kurdjumov, Stanislav Glybovski, Anna Hurshkainen, Andrew Webb, Redha Abdeddaim, Luisa Ciobanu, Irina Melchakova, Pavel Belov
A mechanically tunable and efficient ceramic probe for MR-microscopy at 17 Tesla
published pages: 30011, ISSN: , DOI: 10.1063/1.4998040
AIP Conference Proceedings volume 1883 2020-03-25
2018 M. Sharifian Mazraeh Mollaei, A. Hurshkainen, S. Kurdjumov, S. Glybovski, Constantin Simovski
Decoupling of Two Closely Located Dipole Antennas by a Split-Loop Resonator
published pages: , ISSN: 0048-6604, DOI: 10.1029/2018rs006679
Radio Science 2020-03-25
2018 Anna Hurshkainen, Anton Nikulin, Elodie Georget, Benoit Larrat, Djamel Berrahou, Ana Luisa Neves, Pierre Sabouroux, Stefan Enoch, Irina Melchakova, Pavel Belov, Stanislav Glybovski, Redha Abdeddaim
A Novel Metamaterial-Inspired RF-coil for Preclinical Dual-Nuclei MRI
published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-27327-y
Scientific Reports 8/1 2020-03-25
2018 Georgiy Solomakha, Carel van Leeuwen, Alexander Raaijmakers, Constantin Simovski, Alexander Popugaev, Redha Abdeddaim, Irina Melchakova, Stanislav Glybovski
The dual-mode dipole: A new array element for 7T body imaging with reduced SAR
published pages: , ISSN: 0740-3194, DOI: 10.1002/mrm.27485
Magnetic Resonance in Medicine 2020-03-25
2018 M. S.M. Mollaei, A. Hurshkainen, S. Kurdjumov, S. Glybovski, C. Simovski
Passive electromagnetic decoupling in an active metasurface of dipoles
published pages: 53-61, ISSN: 1569-4410, DOI: 10.1016/j.photonics.2018.10.001
Photonics and Nanostructures - Fundamentals and Applications 32 2020-03-25
2018 Marc Dubois, Lisa Leroi, Zo Raolison, Redha Abdeddaim, Tryfon Antonakakis, Julien de Rosny, Alexandre Vignaud, Pierre Sabouroux, Elodie Georget, Benoit Larrat, Gérard Tayeb, Nicolas Bonod, Alexis Amadon, Franck Mauconduit, Cyril Poupon, Denis Le Bihan, Stefan Enoch
Kerker Effect in Ultrahigh-Field Magnetic Resonance Imaging
published pages: All, ISSN: 2160-3308, DOI: 10.1103/PhysRevX.8.031083
Physical Review X 8/3 2020-03-25
2018 Mikhail Zubkov, Anna A. Hurshkainen, Ekaterina A. Brui, Stanislav B. Glybovski, Mikhail V. Gulyaev, Nikolai V. Anisimov, Dmitry V. Volkov, Yury A. Pirogov, Irina V. Melchakova
Small-animal, whole-body imaging with metamaterial-inspired RF coil
published pages: e3952, ISSN: 0952-3480, DOI: 10.1002/nbm.3952
NMR in Biomedicine 31/8 2020-03-25
2018 M Zubkov, A A Hurshkainen, E A Brui, S B Glybovski, M V Gulyaev, N V Anisimov, D V Volkov, Y A Pirogov, I V Melchakova
Small animal large field of view magnetic resonance imaging with metamaterial-inspired resonator
published pages: 12180, ISSN: 1742-6588, DOI: 10.1088/1742-6596/1092/1/012180
Journal of Physics: Conference Series 1092 2020-03-25
2018 G. Solomakha, S. Glybovski, R. Abbdedaim, C. Simovski, I. Melchakova
A Radiofrequency Coil Based on Hybridized Modes Two Resonant Dipoles
published pages: 12142, ISSN: 1742-6588, DOI: 10.1088/1742-6596/1092/1/012142
Journal of Physics: Conference Series 1092 2020-03-25
2018 Ana L. Neves, Lisa Leroi, Zo Raolison, Nicolas Cochinaire, Thibaut Letertre, Redha Abdeddaïm, Stefan Enoch, Jerome Wenger, Johann Berthelot, Anne-Lise Adenot-Engelvin, Nicolas Malléjac, Franck Mauconduit, Alexandre Vignaud, Pierre Sabouroux
Compressed perovskite aqueous mixtures near their phase transitions show very high permittivities: New prospects for high-field MRI dielectric shimming
published pages: 1753-1765, ISSN: 0740-3194, DOI: 10.1002/mrm.26771
Magnetic Resonance in Medicine 79/3 2020-03-25

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