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MINDED SIGNED

MultIscale precision therapies for NeuroDEvelopmental Disorders

Total Cost €

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EC-Contrib. €

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Partnership

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Project "MINDED" data sheet

The following table provides information about the project.

Coordinator
FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA 

Organization address
address: VIA MOREGO 30
city: GENOVA
postcode: 16163
website: www.iit.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Total cost 6˙796˙800 €
 EC max contribution 3˙398˙400 € (50%)
 Programme 1. H2020-EU.1.3.4. (Increasing structural impact by co-funding activities)
 Code Call H2020-MSCA-COFUND-2016
 Funding Scheme MSCA-COFUND-FP
 Starting year 2018
 Duration (year-month-day) from 2018-01-01   to  2022-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA IT (GENOVA) coordinator 3˙398˙400.00
2    ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA IT (BOLOGNA) partner 0.00
3    BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY US (STANFORD) partner 0.00
4    CHARLES RIVER DISCOVERY RESEARCH SERVICES FINLAND OY FI (KUOPIO) partner 0.00
5    DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG DE (HEIDELBERG) partner 0.00
6    DURHAM COUNTY COUNCIL UK (DURHAM) partner 0.00
7    ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE CH (LAUSANNE) partner 0.00
8    FORSCHUNGSZENTRUM JULICH GMBH DE (JULICH) partner 0.00
9    LULEA TEKNISKA UNIVERSITET SE (LULEA) partner 0.00
10    MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV DE (MUENCHEN) partner 0.00
11    Radboud university medical center NL (Nijmegen) partner 0.00
12    SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE IT (TRIESTE) partner 0.00
13    TEL AVIV UNIVERSITY IL (TEL AVIV) partner 0.00
14    UNIVERSIDADE DO MINHO PT (BRAGA) partner 0.00
15    UNIVERSITE PARIS-SUD FR (ORSAY CEDEX) partner 0.00
16    UNIVERSITY COLLEGE LONDON UK (LONDON) partner 0.00

Map

 Project objective

Neurodevelopmental disorders (NDD) represent an enormous burden for patients, their families, and society. Within EU, the incidence of autism spectrum disorders (ASD) is increasing to over 100 per 10,000 individuals. By comparison, new cases of brain cancers in EU are estimated to be 10 per 10,000. Also, the requirement for lifelong care has a dramatic impact on healthcare costs, with an average lifelong cost per ASD patient of ~ 3.0 MEuro. The societal and economic impact, the growing incidence, and the lack of any cure call for radical changes in the way NDD are approached. At this aim, MINDED will integrate across three major technologies: nanomedicine, for the precise delivery of therapeutic and imaging agents; molecular neuroscience, for the identification of RNAs modulating key gene expression; cognitive neuroscience robotics, for the development of novel sensorimotor interventional approaches. The integration of these technologies requires the establishment of a new class of scientists and entrepreneurs trained to stretch their knowledge over multiple disciplines and think outside conventional silos. MINDED bridges together different vertical silos building common foundations for future interdisciplinary careers. The objective of MINDED is two-fold: develop a highly interdisciplinary post-doctoral training program by integrating nanomedicine, neuroscience and robotics; involve fellows in activities aimed at developing multiscale technologies for NDD. This will be achieved via two training paths: a scientist path, engaging fellows in the development of novel diagnosis and treatment approaches for NDD; a business developer path, engaging fellows on the integration of biomedical technologies in the clinic. MINDED fellows will constitute a new class of scientists and entrepreneurs capable of developing novel treatment and diagnosis approaches for complex genetic diseases and shaping the future integration of nanomedicine and robotics with neurosciences.

 Deliverables

List of deliverables.
First report on communication and dissemination activities Documents, reports 2019-10-18 08:53:41
Second report on communication and dissemination activities Documents, reports 2019-10-18 08:53:35
Information to the Project Officer about the calls Documents, reports 2019-10-18 08:53:39

Take a look to the deliverables list in detail:  detailed list of MINDED deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Martina Pannuzzo, Zachary A McDargh, Markus Deserno
The role of scaffold reshaping and disassembly in dynamin driven membrane fission
published pages: e39441, ISSN: 2050-084X, DOI: 10.7554/elife.39441
eLife 7 2020-03-05
2019 C. Mehring, M. Akselrod, L. Bashford, M. Mace, H. Choi, M. Blüher, A.-S. Buschhoff, T. Pistohl, R. Salomon, A. Cheah, O. Blanke, A. Serino, E. Burdet
Augmented manipulation ability in humans with six-fingered hands
published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-019-10306-w
Nature Communications 10/1 2020-03-05
2019 Monica Frega, Katrin Linda, Jason M. Keller, Güvem Gümüş-Akay, Britt Mossink, Jon-Ruben van Rhijn, Moritz Negwer, Teun Klein Gunnewiek, Katharina Foreman, Nine Kompier, Chantal Schoenmaker, Willem van den Akker, Ilse van der Werf, Astrid Oudakker, Huiqing Zhou, Tjitske Kleefstra, Dirk Schubert, Hans van Bokhoven, Nael Nadif Kasri
Neuronal network dysfunction in a model for Kleefstra syndrome mediated by enhanced NMDAR signaling
published pages: 4928, ISSN: 2041-1723, DOI: 10.1038/s41467-019-12947-3
Nature Communications 10/1 2020-03-05
2019 Nathan C. Foster, Simon J. Bennett, Joe Causer, Digby Elliott, Geoffrey Bird, Spencer J. Hayes
Getting Off to a Shaky Start: Specificity in Planning and Feedforward Control During Sensorimotor Learning in Autism Spectrum Disorder
published pages: , ISSN: 1939-3806, DOI: 10.1002/aur.2214
Autism Research 2020-03-05
2019 Pauline Chevalier, Kyveli Kompatsiari, Francesca Ciardo, Agnieszka Wykowska
Examining joint attention with the use of humanoid robots-A new approach to study fundamental mechanisms of social cognition
published pages: 1-20, ISSN: 1069-9384, DOI: 10.3758/s13423-019-01689-4
Psychonomic Bulletin & Review 2020-03-05
2018 Marianna Colasuonno, Anna Lisa Palange, Rachida Aid, Miguel Ferreira, Hilaria Mollica, Roberto Palomba, Michele Emdin, Massimo Del Sette, Cédric Chauvierre, Didier Letourneur, Paolo Decuzzi
Erythrocyte-Inspired Discoidal Polymeric Nanoconstructs Carrying Tissue Plasminogen Activator for the Enhanced Lysis of Blood Clots
published pages: 12224-12237, ISSN: 1936-0851, DOI: 10.1021/acsnano.8b06021
ACS Nano 12/12 2020-03-05
2019 Jean-François Patri, Julien Diard, Pascal Perrier
Modeling Sensory Preference in Speech Motor Planning: A Bayesian Modeling Framework
published pages: 2339, ISSN: 1664-1078, DOI: 10.3389/fpsyg.2019.02339
Frontiers in Psychology 10 2020-03-05
2019 Irene Senna, Lucilla Cardinali, Alessandro Farnè, Claudio Brozzoli
Aim and Plausibility of Action Chains Remap Peripersonal Space
published pages: 1681, ISSN: 1664-1078, DOI: 10.3389/fpsyg.2019.01681
Frontiers in Psychology 10 2020-03-05
2020 Alessandra Sclip, Thomas C Südhof
LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses
published pages: e53406, ISSN: 2050-084X, DOI: 10.7554/elife.53406
eLife 9 2020-03-05
2019 Alexander B. Cook, Lucka Bibic
Macromolecules, Actually: From Plastics to DNA
published pages: 1, ISSN: 2296-6846, DOI: 10.3389/frym.2019.00126
Frontiers for Young Minds 7 2020-03-05

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The information about "MINDED" are provided by the European Opendata Portal: CORDIS opendata.

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