Explore the words cloud of the PIGSs project. It provides you a very rough idea of what is the project "PIGSs" about.
The following table provides information about the project.
|Coordinator Country||Netherlands [NL]|
|Total cost||4˙998˙103 €|
|EC max contribution||4˙998˙103 € (100%)|
1. H2020-EU.188.8.131.52. (Increasing production efficiency and coping with climate change, while ensuring sustainability and resilience)
|Duration (year-month-day)||from 2017-06-01 to 2021-11-30|
Take a look of project's partnership.
|1||WAGENINGEN UNIVERSITY||NL (WAGENINGEN)||coordinator||1˙153˙795.00|
|2||THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE||UK (CAMBRIDGE)||participant||1˙030˙667.00|
|3||STICHTING WAGENINGEN RESEARCH||NL (WAGENINGEN)||participant||799˙998.00|
|4||INSTITUT DE RECERCA I TECNOLOGIA AGROALIMENTARIES||ES (CALDES DE MONTBUI BARCELONA)||participant||698˙981.00|
|5||STIFTUNG TIERAERZTLICHE HOCHSCHULE HANNOVER||DE (HANNOVER)||participant||408˙000.00|
|6||ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM||NL (AMSTERDAM)||participant||365˙146.00|
|7||DANMARKS TEKNISKE UNIVERSITET||DK (KGS LYNGBY)||participant||292˙765.00|
|8||CEVA SANTE ANIMALE SA||FR (LIBOURNE)||participant||150˙625.00|
|9||CHR. HANSEN A/S||DK (HOERSHOLM)||participant||98˙125.00|
Streptococcus suis is an endemic porcine disease causing causing significant economic losses to the pork meat production industry in all countries where pigs are reared on a large scale. In some countries S. suis is the primary cause of mortality and morbidity in young pigs and the most frequent reason to prescribe antibiotics of the amino-penicillin group as a preventative measure. S. suis is also a zoonotic pathogen of humans and infections reported worldwide has increased significantly in the past years. Within S. suis many different types (serotypes, genotypes, pathotypes) exist causing problems in the development of control strategies targeting all types. Asymptomatic carriage in adult pigs is common and combined with a lack of knowledge on the host-pathogen-environment interactions, are the main reasons for failure to control the endemic nature of this pathogen. The project outputs will impact on on understanding host-pathogen-environment interactions of S. suis infections through the genome sequencing of 1200-1500 S. suis isolates from representative geographic areas of the major pork producing countries and performing genome-wide-association studies with invasive disease and asymptomatic carriage. New diagnostic methods will be developed for global monitoring of infection risk and tested on case-farms. Epidemiology studies will determine risk factors for invasive S. suis disease, including the role of co-infections, and for the first time properly assess the dynamics of the disease on a representative farm. We will increase our understanding of the virulence mechanisms involved in pathogenesis including interactions of S. suis with the innate immune system. The project outputs will strengthen the evidence base for prevention and control strategies through testing of novel conserved vaccine antigens in pigs and prevention strategies based on manipulation of the microbiota and stimulation and maturation of the innate immune system.
|Mutants constructed in selected candidate virulence genes in S. suis strains||Other||2020-03-06 18:15:24|
|Identification of genes required for fitness under in vivo mimicking conditions by Tn-Seq||Documents, reports||2020-03-06 18:15:24|
|Report on the deep analysis of the microbiota composition in healthy and S. suis-diseased piglets||Documents, reports||2020-03-06 18:15:24|
|Report on the â€˜cornerstoneâ€™ species that are predicted to stabilize microbial communities in healthy piglets||Documents, reports||2020-03-06 18:15:24|
|Sequencing of isolate collection||Other||2020-03-06 18:15:24|
|Public Science Event 2||Websites, patent fillings, videos etc.||2020-03-06 18:15:24|
|Genome database containing core genome, meta data, virulence, serotype, MLST, antibiotic resistance||Other||2020-03-06 18:15:24|
|Public Science Event 1||Websites, patent fillings, videos etc.||2020-03-06 18:15:24|
|Collection of isolates||Other||2020-03-06 18:15:24|
|RReport on S. suis gene expression in blood/CSF vs artificial culture media||Documents, reports||2020-03-06 18:15:24|
|Establishment of Project website and information share point||Websites, patent fillings, videos etc.||2020-03-06 18:15:23|
|Report on effects of PRRSV infection on S. suis interaction in lung slices||Documents, reports||2020-03-06 18:15:24|
Take a look to the deliverables list in detail: detailed list of PIGSs deliverables.
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The information about "PIGSS" are provided by the European Opendata Portal: CORDIS opendata.