Explore the words cloud of the TAPAS project. It provides you a very rough idea of what is the project "TAPAS" about.
The following table provides information about the project.
THE UNIVERSITY OF BIRMINGHAM
|Coordinator Country||United Kingdom [UK]|
|Total cost||3˙881˙891 €|
|EC max contribution||3˙881˙891 € (100%)|
1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
|Duration (year-month-day)||from 2018-01-01 to 2021-12-31|
Take a look of project's partnership.
|1||THE UNIVERSITY OF BIRMINGHAM||UK (BIRMINGHAM)||coordinator||546˙575.00|
|2||UNIVERSITEIT MAASTRICHT||NL (MAASTRICHT)||participant||1˙021˙497.00|
|3||THE UNIVERSITY OF READING||UK (READING)||participant||819˙863.00|
|4||LEIBNIZ-INSTITUT FUR ANALYTISCHE WISSENSCHAFTEN-ISAS-EV||DE (DORTMUND)||participant||498˙432.00|
|5||UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT||DE (WURZBURG)||participant||498˙432.00|
|6||ALACRIS THERANOSTICS GMBH||DE (BERLIN)||participant||249˙216.00|
|7||UNIVERSIDAD DE SANTIAGO DE COMPOSTELA||ES (SANTIAGO DE COMPOSTELA)||participant||247˙872.00|
|8||CELLIX LIMITED||IE (Dublin)||partner||0.00|
|9||Intelligent Imaging Innovations GmbH||DE (Göttingen)||partner||0.00|
|10||Nikon Instruments Europe||NL (AMSTERDAM)||partner||0.00|
|11||PIVOT PARK SCREENING CENTRE BV||NL (OSS)||partner||0.00|
|12||SEMMELWEIS EGYETEM||HU (BUDAPEST)||partner||0.00|
|13||SVEUCILISTE U RIJECI||HR (RIJEKA)||partner||0.00|
TAPAS will position Europe at the forefront of innovative research to prevent thrombosis and thromboinflammation, and will train a uniquely-qualified cohort of ESRs in a highly intersectorial and multi-disciplinary programme that will equip them with the knowledge and transferable skills required in the broad biomedical sector. The research will focus on platelets which are small cells in the blood that play a critical role in prevention of excessive bleeding following injury (haemostasis). Activation of platelets in diseased vessels gives rise to thrombotic disorders such as heart attack and stroke, two of the major causes of morbidity and mortality. Patients at risk of thrombosis are treated with medicines that inhibit platelets for life, but many patients still undergo thrombotic episodes or encounter serious bleeds through diminished haemostasis. There is thus an urgent need for novel and safe anti-platelet medicines that powerfully target thrombosis but preserve haemostasis. In TAPAS, an original and innovative approach will be undertaken to find new ways to target thrombosis through co-operation of academic experts in distinct disciplines with key skills from the private sector. TAPAS will generate and integrate knowledge from analytical complex ‘omics’, advanced microscopy, cell biology, microfluidics, in vivo models, contemporary systems biology and high throughput screens to identify new targets for therapeutic intervention and novel lead compounds or biologics. The research skills developed in this programme are applicable to other complex diseases and represent essential training in modern day research for the next cohort of academic and private sector scientists that are able to convert complex biological understanding into new medicines. The shared knowledge and close interaction between beneficiaries and partners makes this programme ideally suited to an EJD and will deliver 15 ESRs in 21st century biomedical research.
|Dissemination and Outreach activity plan completed||Other||2020-04-16 14:17:18|
|Recruitment of 15 ESRs (with statistics of applications)||Other||2020-04-16 14:17:12|
|Organisation of first European Summer School||Other||2020-04-16 14:17:02|
|Organisation of Training Workshops and Conferences||Other||2020-04-16 14:16:57|
|Progress report||Documents, reports||2020-04-16 14:17:22|
|Setup of TAPAS website (updates every 6 months)||Websites, patent fillings, videos etc.||2020-04-16 14:17:07|
Take a look to the deliverables list in detail: detailed list of TAPAS deliverables.
|year||authors and title||journal||last update|
Sanne L.N. Brouns, Isabella Provenzale, Johanna P. van Geffen, Paola E. van der Meijden, Johan W.M. Heemskerk
Localised endothelialâ€based control of platelet aggregation and coagulation under flow: a proofâ€ofâ€principle vesselâ€onâ€aâ€chip study
published pages: , ISSN: 1538-7933, DOI: 10.1111/jth.14719
|Journal of Thrombosis and Haemostasis||2020-02-19|
Isabella Provenzale, Sanne L. N. Brouns, Paola E. J. van der Meijden, Frauke Swieringa, Johan W. M. Heemskerk
Whole Blood Based Multiparameter Assessment of Thrombus Formation in Standard Microfluidic Devices to Proxy In Vivo Haemostasis and Thrombosis
published pages: 787, ISSN: 2072-666X, DOI: 10.3390/mi10110787
Joanne L. Dunster, Amanda J. Unsworth, Alexander P. Bye, Elizabeth J Haining, Marcin A. Sowa, Ying Di, Tanya Sage, Chiara Pallini, Jeremy A. Pike, Alexander.T. Hardy, Bernhard Nieswandt, Ãngel GarcÃa, Steve P. Watson, Natalie S. Poulter, Jonathan M. Gibbins, Alice Y. Pollitt
Interspecies differences in protein expression do not impact the spatiotemporal regulation of GPVI mediated activation
published pages: , ISSN: 1538-7933, DOI: 10.1111/jth.14673
|Journal of Thrombosis and Haemostasis||2019-12-16|
Natalie J. Jooss, Ilaria De Simone, Isabella Provenzale, Delia I. FernÃ¡ndez, Sanne L.N. Brouns, Richard W. Farndale, Yvonne M.C. Henskens, Marijke J.E. Kuijpers, Hugo ten Cate, Paola E.J. van der Meijden, Rachel Cavill, Johan W.M. Heemskerk
Role of Platelet Glycoprotein VI and Tyrosine Kinase Syk in Thrombus Formation on Collagen-Like Surfaces
published pages: 2788, ISSN: 1422-0067, DOI: 10.3390/ijms20112788
|International Journal of Molecular Sciences 20/11||2019-09-26|
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The information about "TAPAS" are provided by the European Opendata Portal: CORDIS opendata.
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