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peLabDisk

Point-of-care molecular diagnostics of psoriasis and eczema – peLabDisk

Total Cost €

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EC-Contrib. €

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Partnership

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 peLabDisk project word cloud

Explore the words cloud of the peLabDisk project. It provides you a very rough idea of what is the project "peLabDisk" about.

superior    consequence    biological    poc    gold    exist    point    made    care    milestones    diseases    prototype    disease    device    caused    supervised    harmful    strategy    valid    individual    construction    pelabdisk    roadmap    lack    plan    created    medical    treating    expertise    closes    munich    experts    skin    extensive    inefficient    ncisd    distinguish    joint    guidance    standard    diagnosis    inflammatory    wrong    forces    communicable    erc    consists    socio    medicine    therapy    packages    molecular    spin    gap    economic    clear    decades    10    university    network    establishing    company    unguided    ineffective    676858    signature    imprecise    psoriasis    handle    mis    patients    post    manufacturing    innovation    diagnostic    first    substantial    diagnostics    treat    waste    grant    schickard    individualised    therapies    feasible    innovative    off    eczema    entrepeneurship    biomarker    microfluidic    competence    foundation    cartridges    distinguished    treatment    hahn    follows    tum    heterogeneity    imcis   

Project "peLabDisk" data sheet

The following table provides information about the project.

Coordinator
KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN 

Organization address
address: ISMANINGER STRASSE 22
city: MUENCHEN
postcode: 81675
website: http://www.med.tu.muenchen.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 150˙000 €
 EC max contribution 150˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-PoC
 Funding Scheme ERC-POC
 Starting year 2018
 Duration (year-month-day) from 2018-03-01   to  2019-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN DE (MUENCHEN) coordinator 150˙000.00

Map

 Project objective

Innovative and effective biological therapies exist to treat non-communicable inflammatory skin diseases (ncISD). However, diagnostic guidance when and how to use them is imprecise; no substantial innovation was made for decades. Due to this lack of innovation, high socio-economic costs are caused by ineffective unguided treatment – a waste of resources. Existing ERC research aims at establishing individualised medicine in ncISD (IMCIS, grant agreement 676858). First success is a biomarker to distinguish psoriasis from eczema. Due to disease heterogeneity, these two ncISD cannot be distinguished in 10% of all cases with current gold standard diagnostics. Treating patients with the wrong therapy as a consequence of mis-diagnosis is inefficient and might even be harmful. This PoC proposal follows the path of IMCIS and closes the gap between ERC research and a prototype device of a point-of-care microfluidic testing device to distinguish psoriasis and eczema based on their molecular signature (peLabDisk). The proposal is feasible, as there is a high level of expertise created by joint forces of researchers of the Technical University of Munich and Hahn-Schickard providing extensive competence in the development, construction and manufacturing of microfluidic cartridges for medical applications. The project plan consists of well-defined work packages and milestones. Furthermore, success of the individual work packages is supervised by experienced experts (TUM Entrepeneurship). This PoC proposal is not the end – there is a clear roadmap and a detailed strategy for the post-PoC phase including potential end-user network and supported foundation of a spin-off company. peLabDisk represents the first approach of molecular diagnostics in the field that is easy-to-handle, robust and valid, as well as economic. It is superior to current gold standard diagnostics. Furthermore, peLabDisk is a use-case for point-of-care molecular diagnostics in complex inflammatory diseases.

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The information about "PELABDISK" are provided by the European Opendata Portal: CORDIS opendata.

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