Opendata, web and dolomites

BiomCatOx SIGNED

Biomimetic Dicopper Architecture for Catalytic Oxygen Activation

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 BiomCatOx project word cloud

Explore the words cloud of the BiomCatOx project. It provides you a very rough idea of what is the project "BiomCatOx" about.

convey    sites    leader    insertion    academic    reactivity    consists    homogeneous    custom    skills    personalized    dicopper    metal    lies    secondment    novelty    connecting    electron    activation    ch    oxidation    powerful    oxidant    stepwise    ros    mild    uk    site    explore    nottingham    selective    oxygen    intramolecular    reaction    spectroscopy    reactive    boost    hydrocarbons    career    benign    competence    species    bioinorganic    training    synthetic    transfer    truncated    provides    internationally    enzymology    copper    gain    heavily    iet    communication    interface    active    nhc    azurin    catalysts    biomcatox    catalyst    merges    catalytic    perspectives    efficient    relay    chemistry    trainings    center    covalent    soft    connection    insights    peptide    o2    conjugate    bond    rigorously    complexes    interdisciplinary    catalysis    strict    organometallic    plan    hydrocarbon    skill    university    rationally    fundamental    bern    discloses    cheap    protein    scientific   

Project "BiomCatOx" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITAET BERN 

Organization address
address: HOCHSCHULSTRASSE 6
city: BERN
postcode: 3012
website: http://www.unibe.ch

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 175˙419 €
 EC max contribution 175˙419 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-03-01   to  2020-02-29

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITAET BERN CH (BERN) coordinator 175˙419.00

Map

 Project objective

BiomCatOx will explore a unique catalyst design for the valorisation of hydrocarbons by oxygen insertion into a C–H bond under mild reaction conditions and using O2 as cheap and benign oxidant. The key concept of BiomCatOx is to rigorously control the activation of O2 and the formation of metal-based reactive oxygen species (ROS) to accomplish selective and catalytic oxidation of hydrocarbons. The novelty of BiomCatOx lies in the design of the catalyst that consists in connecting a heavily truncated protein as electron relay for controllable intramolecular electron transfer (IET) to a synthetic oxidation catalyst. The intramolecular electron transfer can be rationally custom-tailored and therefore provides strict control on the reactivity of the catalytic center and on the formation of the ROS. BiomCatOx will use a stepwise approach involving (i) the development of copper-NHC complexes as powerful catalysts for the formation of ROS and hydrocarbon oxidation, (ii) the development of a copper peptide derived from the azurin active site for efficient electron transfer, and (iii) the covalent connection of the two copper sites into a peptide-complex dicopper conjugate for controlled intramolecular electron transfer. The implementation of BiomCatOx will provide efficient catalytic systems and fundamental insights into electron transfer, and discloses a new catalyst design concept. BiomCatOx is highly interdisciplinary and merges organometallic chemistry, homogeneous catalysis, enzymology, and spectroscopy. This training at the University of Bern (CH) and of Nottingham (UK, secondment) will convey a unique skill set. Together with the personalized career development plan, I will gain significant scientific and soft skills to boost my career and to become an internationally recognized academic leader in Europe at the bioinorganic chemistry/catalysis interface. Communication and management trainings will increase my competence and strongly support my career perspectives.

 Publications

year authors and title journal last update
List of publications.
2018 Matteo Planchestainer, Nathalie Segaud, Muralidharan Shanmugam, Jonathan McMaster, Francesca Paradisi, Martin Albrecht
Carbene in Cupredoxin Protein Scaffolds: Replacement of a Histidine Ligand in the Active Site Substantially Alters Copper Redox Properties
published pages: 10677-10682, ISSN: 1433-7851, DOI: 10.1002/anie.201807168
Angewandte Chemie International Edition 57/33 2020-04-03
2019 Nathalie Ségaud, Jonathan McMaster, Gerard van Koten, Martin Albrecht
Imidazolylidene Cu(II) Complexes: Synthesis Using Imidazolium Carboxylate Precursors and Structure Rearrangement Pathways
published pages: 16047-16058, ISSN: 0020-1669, DOI: 10.1021/acs.inorgchem.9b02568
Inorganic Chemistry 58/23 2020-04-03

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "BIOMCATOX" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "BIOMCATOX" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

MathematicsAnalogies (2019)

Mathematics Analogies

Read More  

MingleIFT (2020)

Multi-color and single-molecule fluorescence imaging of intraflagellar transport in the phasmid chemosensory cilia of C. Elegans

Read More  

NaWaTL (2020)

Narrative, Writing, and the Teotihuacan Language: Exploring Language History Through Phylogenetics, Epigraphy and Iconography

Read More