Opendata, web and dolomites

IPACBIS SIGNED

Identifying preclinical Alzheimer´s disease in the community using a panel of biomarkers among individuals with Subjective Memory Complaints

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 IPACBIS project word cloud

Explore the words cloud of the IPACBIS project. It provides you a very rough idea of what is the project "IPACBIS" about.

interestingly    2y    neuropathology    career    small    stay    alzheimer    risk    therapies    chances    countries    positive    positron    cognition    economical    receive    drugs    host    start    elderly    aged    record    cognitive    back    oacute    population    stages    epidemic    subgroup    200    puncture    academic    tests    anxiety    prevention    fundaci    impairment    cure    experiencing    disease    decline    training    healthy    biomarkers    preserved    neuropsychological    percentage    ad    underlying    smc    optical    preclinical    socio    detected    depression    classified    followed    organization    plasma    coherence    trials    clinical    sensitive    baseline    collaborative    therapy    complaints    brains    united    subjective    benefit    msca    tau    researcher    imaging    sleep    emission    initial    communication    onset    track    techniques    plans    tested    barcelona    independent    connections    publication    specialized    fellowship    symptoms    dementia    lumbar    lack    acute    florbetaben    tomography    memory    biomarker    follow    tenure    join    individuals    international    ace    modifying    mainly   

Project "IPACBIS" data sheet

The following table provides information about the project.

Coordinator
FUNDACIO ACE 

Organization address
address: MARQUES DE SENTMENAT 57
city: BARCELONA
postcode: 8014
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 158˙121 €
 EC max contribution 158˙121 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-RI
 Starting year 2018
 Duration (year-month-day) from 2018-03-01   to  2020-02-29

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FUNDACIO ACE ES (BARCELONA) coordinator 158˙121.00

Map

 Project objective

The dementia epidemic is a growing socio-economical problem in developed countries, including Europe, mainly due to aged population. Alzheimer´s disease (AD), the leading cause of dementia, has currently no prevention or cure. Identifying AD at early stages will likely improve the chances of developing an effective therapy. AD-related changes can be detected in brains of healthy individuals many years before the onset of cognitive decline using biomarkers. Testing all elderly healthy individuals would not be cost-effective, but interestingly many of them experience subjective memory complaints (SMC) but show preserved cognition when tested. Although conditions such as drugs, depression, anxiety or lack of sleep may be the underlying cause of SMC, a small percentage of individuals with SMC are experiencing the very initial symptoms of AD. The aim of this proposal is to identify which subgroup of individuals with SMC is at risk of developing AD dementia in the future. 200 individuals with SMC will be followed-up for 2y and tested with positron emission tomography with Florbetaben, plasma, lumbar puncture, optical coherence tomography and very sensitive neuropsychological tests at the Fundació ACE in Barcelona. Those finally classified as preclinical AD due to positive biomarkers at baseline and cognitive impairment at follow-up will be offered to join clinical trials for disease-modifying therapies against AD. The MSCA fellowship will allow the researcher to establish an independent career back in Europe after a stay in the United States, start academic tenure-track, improve her publication record, and receive specialized training in novel biomarker techniques and the preclinical phase of AD. The host organization will benefit from the researcher´s knowledge in tau imaging and neuropathology and her international connections to establish new collaborative projects. Plans for communication, exploitation and dissemination of the results will be established.

 Publications

year authors and title journal last update
List of publications.
2020 Marta Marquié, Sergi Valero, Miguel Castilla-Marti, Joan Martínez, Octavio Rodríguez-Gómez, Ángela Sanabria, Juan Pablo Tartari, Gemma C. Monté-Rubio, Oscar Sotolongo-Grau, Montserrat Alegret, Alba Pérez-Cordón, Natalia Roberto, Itziar de Rojas, Sonia Moreno-Grau, Laura Montrreal, Isabel Hernández, Maitee Rosende-Roca, Ana Mauleón, Liliana Vargas, Carla Abdelnour, Silvia Gil, Ester Esteb
Association between retinal thickness and β-amyloid brain accumulation in individuals with subjective cognitive decline: Fundació ACE Healthy Brain Initiative
published pages: , ISSN: 1758-9193, DOI: 10.1186/s13195-020-00602-9
Alzheimer\'s Research & Therapy 12/1 2020-04-15
2019 Marta Marquié, Miguel Castilla-Martí, Sergi Valero, Joan Martínez, Domingo Sánchez, Isabel Hernández, Maitée Rosende-Roca, Liliana Vargas, Ana Mauleón, Octavio Rodríguez-Gómez, Carla Abdelnour, Silvia Gil, Miguel A. Santos-Santos, Montserrat Alegret, Ana Espinosa, Gemma Ortega, Alba Pérez-Cordón, Ángela Sanabria, Natalia Roberto, Sonia Moreno-Grau, Itziar de Rojas, Rafael Simó, Andree
Visual impairment in aging and cognitive decline: experience in a Memory Clinic
published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-019-45055-9
Scientific Reports 9/1 2019-08-05

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "IPACBIS" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "IPACBIS" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

DEF2DEV (2019)

Identification of the mode of action of plant defensins during root development and plant defense responses.

Read More  

CREDit (2020)

Chronological REference Datasets and Sites (CREDit) towards improved accuracy and precision in luminescence-based chronologies

Read More  

EngPTC2 (2019)

Exploring new technologies for the next generation pulse tube cryocooler below 2K

Read More