Opendata, web and dolomites

BESIDE SIGNED

Bile acids and epithelial stem cells in intestinal development

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 BESIDE project word cloud

Explore the words cloud of the BESIDE project. It provides you a very rough idea of what is the project "BESIDE" about.

hypothesis    microorganisms    git    amino    cell    microbiota    life    colonisation    stem    bsh    morphological    deconjugates    maturation    mechanisms    flow    apc    rapid    beside    cytometry    edge    influences    conduct    bacterial    therapeutics    line    transfer    suggesting    scientist    experiments    cutting    microbiome    tract    community    understand    innovative    host    acids    culture    series    gut    multinational    society    hydrolase    period    extrapolate    relationship    first    independent    coincident    critically    functional    iescs    world    biotech    metabolic    fellowship    perkin    gain    functions    company    salt    moment    neonate    function    contributions    division    influence    colonisers    human    birth    begins    skills    bile    secondment    barrier    metabolites    msca    vivo    economy    conjugated    imaging    stakeholders    underlying    she    antenatal    public    cells    additional    inform    gastrointestinal    continues    centre    continue    intestinal    proliferation    professional    career    model    elmer    bacteria   

Project "BESIDE" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK 

Organization address
address: WESTERN ROAD
city: Cork
postcode: T12 YN60
website: www.ucc.ie

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Ireland [IE]
 Total cost 175˙866 €
 EC max contribution 175˙866 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-04-01   to  2020-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK IE (Cork) coordinator 175˙866.00

Map

Leaflet | Map data © OpenStreetMap contributors, CC-BY-SA, Imagery © Mapbox

 Project objective

This project will investigate how gut bacteria (the microbiota) influence development of the human gastrointestinal tract (GIT) through innovative research at a world leading research centre (the APC Microbiome Institute) and secondment to the R&D division of a leading multinational biotech company (Perkin Elmer). The gut microbiota comprises a complex community of microorganisms that provide essential metabolic functions in the host. The colonisation of the gut begins during the antenatal period, continues after the moment of birth and is coincident with rapid morphological and functional gut maturation suggesting that these early colonisers and their metabolites have an impact on GIT barrier development. Bile salt hydrolase (BSH) activity (which deconjugates amino-conjugated bile acids in the gut), is present among the first colonisers of the GIT. Thus, the BESIDE project hypothesis is that this bacterial BSH activity critically affects GIT development and maturation in early life. To understand the mechanisms underlying this relationship, BESIDE will conduct a series of experiments to i) determine how BSH activity influences intestinal stem cells (IESCs); ii) identify the effects on proliferation of these IESCs and iii) extrapolate the obtained results using an in vivo model. BESIDE presents a novel approach using methods based on cutting-edge cell culture, flow cytometry and cell imaging to gain knowledge which is likely to inform the future development of therapeutics to improve barrier function in the neonate. Additional objectives of BESIDE include dissemination and transfer of knowledge to relevant stakeholders (as well as to the general public) and the development of management and career development skills. This, in line with the Work Programme for the MSCA fellowship, will help the applicant to become an independent professional scientist in the field so that she will continue to make significant contributions to the European society and economy.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "BESIDE" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "BESIDE" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

Photonic Radar (2019)

Implementation of Long Reach Hybrid Photonic Radar System and convergence over FSO and PON Networks

Read More  

DNANanoProbes (2019)

Design of light-harvesting DNA-nanoprobes with ratiometric signal amplification for fluorescence imaging of live cells.

Read More  

PleasDef (2019)

Exploring Women’s Sexual Pleasure Deficit

Read More