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Bacterial regulation of Apis neurophysiology

Total Cost €


EC-Contrib. €






 BRAIN project word cloud

Explore the words cloud of the BRAIN project. It provides you a very rough idea of what is the project "BRAIN" about.

gut    ecology    economic    microbiome    animal    ants    published    genome    grown    health    regions    disciplinary    axis    fish    symbioses    molecular    elusive    phenotypes    domesticated    easily    isotope    exponentially    microbes    function    harvest    mammalian    extended    species    realize    evolutionary    think    metabolites    ecologist    tangible    symbionts    data    transfer    organization    food    microbiota    insemination    neurotranscriptomics    conceptual    insects    training    manipulation    social    previously    he    characterization    groups    tracking    map    symbiont    brain    labelling    apis    biologists    feasible    predict    diversity    gene    microscopy    bacteria    little    symbiosis    modifications    neurophysiology    bioinformatics    synergistic    interactions    expression    physiological    cultured    transcriptomics    understand    bacterial    area    honeybee    investigations    considerable    neurological    hosts    experimental    inter    metabolic    ambitions    behavioural    theory    traits    secure    benefits    primary    bees    mellifera    sequencing    microbial    none    host    microbiology   

Project "BRAIN" data sheet

The following table provides information about the project.


Organization address
address: Quartier Unil-Centre Bâtiment Unicentre
postcode: 1015

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 175˙419 €
 EC max contribution 175˙419 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-07-01   to  2020-06-30


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITE DE LAUSANNE CH (LAUSANNE) coordinator 175˙419.00


 Project objective

Gut microbes are known to affect the neurophysiology of their hosts and genome sequencing now easily allows metabolic characterization of elusive microbial diversity that cannot be cultured. While investigations on the neurological and behavioural consequences of mammalian gut symbionts have grown exponentially in recent years, little is known about the ‘gut microbiota–brain axis’ in insects of major economic interest. The applicant is a molecular evolutionary ecologist who previously used gene expression data to predict physiological modifications in the honeybee after insemination and published a comparative analysis of bacterial symbionts across ants. He now aims to realize an inter-disciplinary program to map the neurological and behavioural extended phenotypes of gut symbionts in bees. Through experimental approaches of microbiome manipulation, neurotranscriptomics, behavioural-tracking, FISH, and isotope-labelling of bacterial metabolites, the project seeks to understand: (i) the extent to which Apis mellifera gut symbionts affect host brain function by identifying the specific bacteria, their metabolic products, and the brain regions involved in host-symbiont interactions, and (ii) assess whether these processes affect behavioural traits relevant for the social organization of bees. None of these objectives have been addressed before and achieving them has high potential to change the way in which biologists think about bacterial symbioses and animal behaviour. The project includes training-through-research for the applicant in microbiology, behavioural ecology, microscopy and bioinformatics, and considerable knowledge transfer in transcriptomics and conceptual symbiosis theory from the applicant to the host groups. Although challenging in its ambitions, the project is synergistic and feasible, and will allow the European Research Area to harvest tangible benefits to improve the health of a domesticated species of primary importance to secure food production.

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The information about "BRAIN" are provided by the European Opendata Portal: CORDIS opendata.

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