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Bacterial regulation of Apis neurophysiology

Total Cost €


EC-Contrib. €






 BRAIN project word cloud

Explore the words cloud of the BRAIN project. It provides you a very rough idea of what is the project "BRAIN" about.

food    neurophysiology    traits    published    microbes    neurological    experimental    symbiosis    bacteria    gut    groups    honeybee    considerable    theory    regions    bioinformatics    modifications    ants    he    genome    predict    tracking    realize    primary    little    biologists    health    microbiota    transfer    organization    bacterial    physiological    area    elusive    microscopy    microbial    animal    map    data    grown    expression    easily    insects    host    phenotypes    domesticated    isotope    disciplinary    evolutionary    manipulation    mammalian    species    understand    apis    symbiont    harvest    fish    hosts    ecology    metabolites    molecular    social    transcriptomics    investigations    none    synergistic    conceptual    diversity    metabolic    feasible    mellifera    symbioses    previously    training    economic    neurotranscriptomics    gene    cultured    characterization    inter    secure    tangible    interactions    microbiome    labelling    sequencing    extended    function    behavioural    exponentially    think    benefits    ambitions    bees    insemination    axis    symbionts    ecologist    brain    microbiology   

Project "BRAIN" data sheet

The following table provides information about the project.


Organization address
address: Quartier Unil-Centre Bâtiment Unicentre
postcode: 1015

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 175˙419 €
 EC max contribution 175˙419 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-07-01   to  2020-06-30


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITE DE LAUSANNE CH (LAUSANNE) coordinator 175˙419.00


 Project objective

Gut microbes are known to affect the neurophysiology of their hosts and genome sequencing now easily allows metabolic characterization of elusive microbial diversity that cannot be cultured. While investigations on the neurological and behavioural consequences of mammalian gut symbionts have grown exponentially in recent years, little is known about the ‘gut microbiota–brain axis’ in insects of major economic interest. The applicant is a molecular evolutionary ecologist who previously used gene expression data to predict physiological modifications in the honeybee after insemination and published a comparative analysis of bacterial symbionts across ants. He now aims to realize an inter-disciplinary program to map the neurological and behavioural extended phenotypes of gut symbionts in bees. Through experimental approaches of microbiome manipulation, neurotranscriptomics, behavioural-tracking, FISH, and isotope-labelling of bacterial metabolites, the project seeks to understand: (i) the extent to which Apis mellifera gut symbionts affect host brain function by identifying the specific bacteria, their metabolic products, and the brain regions involved in host-symbiont interactions, and (ii) assess whether these processes affect behavioural traits relevant for the social organization of bees. None of these objectives have been addressed before and achieving them has high potential to change the way in which biologists think about bacterial symbioses and animal behaviour. The project includes training-through-research for the applicant in microbiology, behavioural ecology, microscopy and bioinformatics, and considerable knowledge transfer in transcriptomics and conceptual symbiosis theory from the applicant to the host groups. Although challenging in its ambitions, the project is synergistic and feasible, and will allow the European Research Area to harvest tangible benefits to improve the health of a domesticated species of primary importance to secure food production.

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The information about "BRAIN" are provided by the European Opendata Portal: CORDIS opendata.

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