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DEEPADAPT SIGNED

The molecular drivers of deep-sea adaptation in brittle stars

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 DEEPADAPT project word cloud

Explore the words cloud of the DEEPADAPT project. It provides you a very rough idea of what is the project "DEEPADAPT" about.

abundant    marine    thirds    environmental    highlighting    convergent    ophiuroidea    examine    shallow    resilience    phylogenetic    phylogenomics    positive    displaying    adaptive    resequencing    allele    evolution    genealogical    800    adaptations    intend    surprisingly    group    environment    diversity    decipher    independently    brittle    molecular    exon    protein    planet    frequency    candidate    genes    capture    genomes    world    life    reference    spanning    little    bottoms    echinoderms    bathymetric    sea    scan    individuals    distantly    stress    quality    genomics    tools    depths    colonized    harsh    underlying    representative    environments    mechanisms    species    complexes    dataset    ocean    taxa    deep    least    transitions    120    shifts    water    hints    adaptation    covers    stars    400    invertebrates    discordance    analytic    first    purpose    gt    cryptic    analyzing    keywords    ongoing    deciphering    genome    biodiversity    metabolic    times    entire    generation   

Project "DEEPADAPT" data sheet

The following table provides information about the project.

Coordinator
INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER 

Organization address
address: 1625 ROUTE DE SAINTE ANNE ZONE INDUSTRIELLE DE LA POINTE DU DIABLE
city: PLOUZANE
postcode: 29280
website: http://www.ifremer.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 270˙918 €
 EC max contribution 270˙918 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-GF
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2022-01-20

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER FR (PLOUZANE) coordinator 270˙918.00
2    Museums Victoria AU (Melbourne) partner 0.00

Map

Leaflet | Map data © OpenStreetMap contributors, CC-BY-SA, Imagery © Mapbox

 Project objective

The deep-sea covers about two-thirds of the world’s ocean bottoms; yet, it is one of the least known environments of the planet. Given its harsh environmental conditions, life in high depths requires several specific metabolic adaptations. Surprisingly, little is known about the molecular mechanisms underlying adaptation to such environments. Which and how many genes are involved in adaptation? What is the extent of convergent evolution across distantly related taxa? Brittle stars (Ophiuroidea) are a useful group of marine invertebrates to study for this purpose, as they are abundant in the deep-sea and they colonized this environment several times independently, thus highlighting their strong adaptive abilities. Here, I intend to investigate deep-sea adaptation using a comparative genomics approach and state of the art analytic tools. I will first use an existing dataset to examine adaptive protein evolution (genealogical discordance and positive selection), by comparing 400 genes across 800 species of shallow- and deep-water brittle stars spanning the entire Ophiuroidea diversity. I will then focus on five cryptic species complexes representative of the major bathymetric transitions, by analyzing >10,000 genes generated from exon-capture and focusing on specific candidate genes. Finally, I will investigate allele frequency shifts among depths for two species displaying a wide bathymetric range using a genome scan approach (generation of two high-quality reference genomes; whole genome resequencing for 120 individuals). With these three approaches spanning a wide phylogenetic range, I intend to decipher the molecular mechanisms underlying deep-sea adaptation. This is of high importance because deciphering mechanisms of stress-driven adaptation may provide hints on the resilience of deep marine biodiversity to the ongoing environmental changes. Keywords: deep-sea; adaptation; phylogenomics; genome scan; positive selection; exon capture; Ophiuroidea; echinoderms

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The information about "DEEPADAPT" are provided by the European Opendata Portal: CORDIS opendata.

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