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DEEPADAPT SIGNED

The molecular drivers of deep-sea adaptation in brittle stars

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 DEEPADAPT project word cloud

Explore the words cloud of the DEEPADAPT project. It provides you a very rough idea of what is the project "DEEPADAPT" about.

keywords    taxa    least    reference    shallow    intend    positive    resequencing    spanning    brittle    group    thirds    environmental    depths    bathymetric    representative    genomes    stars    evolution    exon    adaptive    echinoderms    gt    purpose    capture    candidate    molecular    ongoing    resilience    120    sea    400    quality    abundant    environments    convergent    surprisingly    metabolic    diversity    800    decipher    bottoms    world    environment    genome    adaptation    ophiuroidea    water    genes    displaying    first    marine    protein    underlying    phylogenetic    planet    discordance    adaptations    frequency    tools    colonized    mechanisms    times    examine    cryptic    covers    individuals    phylogenomics    dataset    genomics    allele    little    independently    analyzing    ocean    invertebrates    scan    hints    shifts    analytic    species    biodiversity    harsh    generation    deep    stress    deciphering    distantly    highlighting    life    entire    transitions    complexes    genealogical   

Project "DEEPADAPT" data sheet

The following table provides information about the project.

Coordinator
INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER 

Organization address
address: 1625 ROUTE DE SAINTE ANNE ZONE INDUSTRIELLE DE LA POINTE DU DIABLE
city: PLOUZANE
postcode: 29280
website: http://www.ifremer.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 270˙918 €
 EC max contribution 270˙918 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-GF
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2022-01-20

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER FR (PLOUZANE) coordinator 270˙918.00
2    Museums Victoria AU (Melbourne) partner 0.00

Map

 Project objective

The deep-sea covers about two-thirds of the world’s ocean bottoms; yet, it is one of the least known environments of the planet. Given its harsh environmental conditions, life in high depths requires several specific metabolic adaptations. Surprisingly, little is known about the molecular mechanisms underlying adaptation to such environments. Which and how many genes are involved in adaptation? What is the extent of convergent evolution across distantly related taxa? Brittle stars (Ophiuroidea) are a useful group of marine invertebrates to study for this purpose, as they are abundant in the deep-sea and they colonized this environment several times independently, thus highlighting their strong adaptive abilities. Here, I intend to investigate deep-sea adaptation using a comparative genomics approach and state of the art analytic tools. I will first use an existing dataset to examine adaptive protein evolution (genealogical discordance and positive selection), by comparing 400 genes across 800 species of shallow- and deep-water brittle stars spanning the entire Ophiuroidea diversity. I will then focus on five cryptic species complexes representative of the major bathymetric transitions, by analyzing >10,000 genes generated from exon-capture and focusing on specific candidate genes. Finally, I will investigate allele frequency shifts among depths for two species displaying a wide bathymetric range using a genome scan approach (generation of two high-quality reference genomes; whole genome resequencing for 120 individuals). With these three approaches spanning a wide phylogenetic range, I intend to decipher the molecular mechanisms underlying deep-sea adaptation. This is of high importance because deciphering mechanisms of stress-driven adaptation may provide hints on the resilience of deep marine biodiversity to the ongoing environmental changes. Keywords: deep-sea; adaptation; phylogenomics; genome scan; positive selection; exon capture; Ophiuroidea; echinoderms

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The information about "DEEPADAPT" are provided by the European Opendata Portal: CORDIS opendata.

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