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DEEPADAPT SIGNED

The molecular drivers of deep-sea adaptation in brittle stars

Total Cost €

0

EC-Contrib. €

0

Partnership

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 DEEPADAPT project word cloud

Explore the words cloud of the DEEPADAPT project. It provides you a very rough idea of what is the project "DEEPADAPT" about.

scan    genomes    reference    highlighting    quality    deciphering    deep    protein    generation    invertebrates    adaptive    shallow    echinoderms    sea    water    world    covers    distantly    transitions    independently    candidate    decipher    diversity    capture    metabolic    discordance    intend    brittle    resilience    gt    analyzing    mechanisms    surprisingly    adaptation    cryptic    environment    ophiuroidea    phylogenomics    tools    120    resequencing    800    shifts    analytic    ongoing    allele    biodiversity    least    stars    dataset    underlying    genomics    little    bottoms    convergent    life    examine    genome    exon    group    representative    depths    environments    stress    marine    displaying    harsh    environmental    keywords    colonized    entire    taxa    planet    bathymetric    spanning    phylogenetic    molecular    hints    times    individuals    positive    genealogical    genes    complexes    thirds    ocean    species    abundant    first    frequency    400    adaptations    evolution    purpose   

Project "DEEPADAPT" data sheet

The following table provides information about the project.

Coordinator
INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER 

Organization address
address: 1625 ROUTE DE SAINTE ANNE ZONE INDUSTRIELLE DE LA POINTE DU DIABLE
city: PLOUZANE
postcode: 29280
website: http://www.ifremer.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 270˙918 €
 EC max contribution 270˙918 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-GF
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2022-01-20

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER FR (PLOUZANE) coordinator 270˙918.00
2    Museums Victoria AU (Melbourne) partner 0.00

Map

 Project objective

The deep-sea covers about two-thirds of the world’s ocean bottoms; yet, it is one of the least known environments of the planet. Given its harsh environmental conditions, life in high depths requires several specific metabolic adaptations. Surprisingly, little is known about the molecular mechanisms underlying adaptation to such environments. Which and how many genes are involved in adaptation? What is the extent of convergent evolution across distantly related taxa? Brittle stars (Ophiuroidea) are a useful group of marine invertebrates to study for this purpose, as they are abundant in the deep-sea and they colonized this environment several times independently, thus highlighting their strong adaptive abilities. Here, I intend to investigate deep-sea adaptation using a comparative genomics approach and state of the art analytic tools. I will first use an existing dataset to examine adaptive protein evolution (genealogical discordance and positive selection), by comparing 400 genes across 800 species of shallow- and deep-water brittle stars spanning the entire Ophiuroidea diversity. I will then focus on five cryptic species complexes representative of the major bathymetric transitions, by analyzing >10,000 genes generated from exon-capture and focusing on specific candidate genes. Finally, I will investigate allele frequency shifts among depths for two species displaying a wide bathymetric range using a genome scan approach (generation of two high-quality reference genomes; whole genome resequencing for 120 individuals). With these three approaches spanning a wide phylogenetic range, I intend to decipher the molecular mechanisms underlying deep-sea adaptation. This is of high importance because deciphering mechanisms of stress-driven adaptation may provide hints on the resilience of deep marine biodiversity to the ongoing environmental changes. Keywords: deep-sea; adaptation; phylogenomics; genome scan; positive selection; exon capture; Ophiuroidea; echinoderms

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The information about "DEEPADAPT" are provided by the European Opendata Portal: CORDIS opendata.

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