Opendata, web and dolomites

NEUROTILES SIGNED

Bioengineered hippocampal organoids for epilepsy treatment

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 NEUROTILES project word cloud

Explore the words cloud of the NEUROTILES project. It provides you a very rough idea of what is the project "NEUROTILES" about.

learning    complementary    repair    idea    intelligence    central    era    causing    generating    responsive    psychiatric    stems    neural    ultimately    mammalian    generate    mini    organoids    synergetic    uncontrolled    thrive    brains    options    linked    first    drug    deep    foundation    syndrome    nowadays    brain    regenerative    treatment    urgent    invasive    parts    carefully    advent    epilepsy    engage    neurosurgery    enhanced    memory    repairing    lobe    co    social    seizure    tle    progressive    transplants    medications    resistance    burden    highest    organoid    severe    interaction    thanks    heal    least    crucially    unprecedented    appealing    biohybrid    stimulation    unexplored    human    stigma    engineered    tools    establishment    time    carries    engineering    breaking    push    interventions    ensues    strategies    replacement    medicine    artificial    frequent    ground    cells    ignite    hippocampus    morbidities    surrogate    innovative    structure    neurotiles    tissue    life    dish    nanotechnology    demands    threatening    framework    revolutionary    stem    dialogue    pursue    temporal    cognitive    disorder    disease    diseased    remarkably   

Project "NEUROTILES" data sheet

The following table provides information about the project.

Coordinator
TECHNISCHE UNIVERSITEIT EINDHOVEN 

Organization address
address: GROENE LOPER 3
city: EINDHOVEN
postcode: 5612 AE
website: www.tue.nl/en

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 177˙598 €
 EC max contribution 177˙598 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2020-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TECHNISCHE UNIVERSITEIT EINDHOVEN NL (EINDHOVEN) coordinator 177˙598.00

Map

 Project objective

Epilepsy is a life-threatening progressive disorder causing uncontrolled activity of the brain (seizure); it carries among the highest burden of disease and significant social stigma. Temporal lobe epilepsy (TLE) is the most frequent syndrome, the least responsive to medications and the most linked to severe psychiatric and cognitive co-morbidities. When drug resistance ensues, neurosurgery and deep-brain stimulation are invasive options to carefully consider. Thus, TLE treatment demands urgent innovative interventions.

Is it possible to generate ‘replacement parts’ to heal the diseased brain? The idea of repairing the brain using engineered transplants is nowadays more appealing than ever thanks to the ground-breaking advent of ‘mini-brains in a dish’ (brain organoids). Remarkably, brain organoids can be derived from human stem cells, thus carrying unique potential for targeted studies. However, their application in regenerative medicine has yet to thrive. Therefore, the interaction of brain organoids with mammalian brain tissue remains unexplored.

In this project, I engage in the challenge of generating surrogate brain areas as transplants for epilepsy treatment. Specifically, I will focus on the hippocampus, a central structure in learning and memory which is crucially involved in TLE. I will push an unprecedented biohybrid design based on the synergetic exploitation of organoid technology and innovative neural engineering tools to pursue, for the first time ever, the establishment of a dialogue between engineered and mammalian brain tissue. The foundation of NEUROTILES stems in the emerging concept that brain repair strategies from regenerative medicine and neural engineering are distinct yet complementary. In the era of artificial intelligence and nanotechnology, NEUROTILES will promote a revolutionary framework for brain repair strategies and ultimately ignite the establishment of the novel field of ‘enhanced’ regenerative medicine.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "NEUROTILES" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "NEUROTILES" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

DIGILEAD (2020)

Digital leadership, well-being and performance in organizations

Read More  

CLIMACY (2020)

Practices of Climate Diplomacy and Uneven Policy Responses on Climate Change on Human Mobility

Read More  

Photonic Radar (2019)

Implementation of Long Reach Hybrid Photonic Radar System and convergence over FSO and PON Networks

Read More