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HelpUS SIGNED

Pioneering focused Ultrasounds as a new non-invasive deep brain stimulation for a causal investigation of empathy related brain processes in moral learning and decision making

Total Cost €

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EC-Contrib. €

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Partnership

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 HelpUS project word cloud

Explore the words cloud of the HelpUS project. It provides you a very rough idea of what is the project "HelpUS" about.

painful    emotions    affective    transformed    untreatable    explore    insula    vicarious    brand    limbic    motivating    optimize    harm    representation    incorporate    associating    modulate    individuals    cingulate    kick    transforming    transform    powerless    stimulation    benefits    mechanistic    disorders    prosociality    cognition    kicking    depends    tools    noninvasively    interventions    neuroscience    ultrasounds    learning    facial    causal    anterior    compare    expression    relationship    alter    showing    had    neural    stop    pave    unleash    leaning    humans    deep    suggesting    select    antisocial    brake    brain    frustratingly    decision    us    pain    testable    feel    cooperation    cooperate    hypotheses    outcomes    thereby    deeper    themselves    push    actions    successful    balance    inform    captures    self    friend    structures    selectively    stead    models    equation    kicked    context    computational    hypothesis    generally    fmri    remained    altering    regions    provides    currency    negative    empathy    social    nature    barrier    behavior   

Project "HelpUS" data sheet

The following table provides information about the project.

Coordinator
KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW 

Organization address
address: KLOVENIERSBURGWAL 29 HET TRIPPENHUIS
city: AMSTERDAM
postcode: 1011 JV
website: www.knaw.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 1˙500˙000 €
 EC max contribution 1˙500˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-STG
 Funding Scheme ERC-STG
 Starting year 2018
 Duration (year-month-day) from 2018-07-01   to  2023-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW NL (AMSTERDAM) coordinator 1˙500˙000.00

Map

 Project objective

The success of humans depends on their ability to cooperate. Cooperation requires learning to avoid actions that harm others and select those that balance benefits for self and others. Reinforcement leaning captures how individuals learn to optimize benefits for themselves, by associating actions and outcomes for the self. The social context requires to incorporate outcomes for others into that equation by transforming them into the currency used to value our own outcomes. Research on empathy, by suggesting that we transform the emotions of others into neural representation of how we would feel in their stead, provides testable mechanistic hypotheses of how we do that. The painful facial expression of our friend after we kick him would be transformed into the pain we would feel when kicked, associating kicking with negative value, thereby motivating us to stop kicking. Testing this hypothesis would require altering brain activity in the anterior insula and cingulate involved in this process, and showing that these changes alter decision making. Because current tools in humans cannot selectively modulate activity in these deeper regions we however remain frustratingly powerless to do so. Here we will develop a brand new method using ultrasounds to modulate brain activity at any depth to brake down this barrier. Using fmri, we will measure vicarious activity and compare it with computational models. This will push our understanding of our social nature to a new computational level, and pave the way to a more causal understanding of prosociality that can inform successful interventions for so far untreatable antisocial disorders. More generally deep brain stimulation via US, and the understanding of how US modulate brain activity, will unleash affective neuroscience to noninvasively explore what had remained beyond our reach: the causal relationship between deeper (limbic) structures and behavior and cognition.

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The information about "HELPUS" are provided by the European Opendata Portal: CORDIS opendata.

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lastchecktime (2021-01-21 2:58:23) correctly updated