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HelpUS SIGNED

Pioneering focused Ultrasounds as a new non-invasive deep brain stimulation for a causal investigation of empathy related brain processes in moral learning and decision making

Total Cost €

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EC-Contrib. €

0

Partnership

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 HelpUS project word cloud

Explore the words cloud of the HelpUS project. It provides you a very rough idea of what is the project "HelpUS" about.

leaning    benefits    insula    computational    deep    mechanistic    modulate    themselves    thereby    optimize    nature    prosociality    generally    brand    explore    altering    noninvasively    humans    regions    painful    ultrasounds    motivating    hypotheses    us    successful    select    empathy    behavior    incorporate    push    cognition    stop    kick    barrier    unleash    feel    neural    cooperation    testable    cooperate    stead    remained    deeper    currency    neuroscience    expression    depends    learning    had    associating    pave    balance    suggesting    structures    limbic    representation    self    actions    inform    brain    equation    individuals    fmri    stimulation    pain    anterior    hypothesis    transform    transformed    social    models    antisocial    showing    friend    untreatable    vicarious    powerless    kicking    facial    negative    causal    brake    compare    emotions    selectively    alter    outcomes    captures    transforming    affective    cingulate    harm    provides    interventions    tools    decision    relationship    disorders    kicked    context    frustratingly   

Project "HelpUS" data sheet

The following table provides information about the project.

Coordinator
KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW 

Organization address
address: KLOVENIERSBURGWAL 29 HET TRIPPENHUIS
city: AMSTERDAM
postcode: 1011 JV
website: www.knaw.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 1˙500˙000 €
 EC max contribution 1˙500˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-STG
 Funding Scheme ERC-STG
 Starting year 2018
 Duration (year-month-day) from 2018-07-01   to  2023-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW NL (AMSTERDAM) coordinator 1˙500˙000.00

Map

 Project objective

The success of humans depends on their ability to cooperate. Cooperation requires learning to avoid actions that harm others and select those that balance benefits for self and others. Reinforcement leaning captures how individuals learn to optimize benefits for themselves, by associating actions and outcomes for the self. The social context requires to incorporate outcomes for others into that equation by transforming them into the currency used to value our own outcomes. Research on empathy, by suggesting that we transform the emotions of others into neural representation of how we would feel in their stead, provides testable mechanistic hypotheses of how we do that. The painful facial expression of our friend after we kick him would be transformed into the pain we would feel when kicked, associating kicking with negative value, thereby motivating us to stop kicking. Testing this hypothesis would require altering brain activity in the anterior insula and cingulate involved in this process, and showing that these changes alter decision making. Because current tools in humans cannot selectively modulate activity in these deeper regions we however remain frustratingly powerless to do so. Here we will develop a brand new method using ultrasounds to modulate brain activity at any depth to brake down this barrier. Using fmri, we will measure vicarious activity and compare it with computational models. This will push our understanding of our social nature to a new computational level, and pave the way to a more causal understanding of prosociality that can inform successful interventions for so far untreatable antisocial disorders. More generally deep brain stimulation via US, and the understanding of how US modulate brain activity, will unleash affective neuroscience to noninvasively explore what had remained beyond our reach: the causal relationship between deeper (limbic) structures and behavior and cognition.

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The information about "HELPUS" are provided by the European Opendata Portal: CORDIS opendata.

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