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LEAP-EXTREME SIGNED

Local Edaphic Adaptation in Plants through Leveraging an Extremophile Model

Total Cost €

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EC-Contrib. €

0

Partnership

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 LEAP-EXTREME project word cloud

Explore the words cloud of the LEAP-EXTREME project. It provides you a very rough idea of what is the project "LEAP-EXTREME" about.

hypertolerance    transcriptomics    enhanced    biotechnology    rates    repeated    questions    minerals    metals    pioneering    local    earth    natural    genome    inorganic    continuous    genotype    relation    halleri    linkage    lithosphere    advantage    multiple    ordinary    cadmium    biologically    harbouring    conduct    effect    function    causal    extremophile    ecosystems    resequencing    zinc    never    changeable    breeding    crosses    trait    species    metal    phenotyping    arabidopsis    intermittently    plasticity    lack    contaminated    traits    restoration    surface    answer    genetic    recording    few    leaves    divergent    discontinuous    attenuated    complemented    plants    enabled    nutrient    associations    wild    adaptations    hyperaccumulation    context    fundamental    soil    soils    placed    implementing    mapping    insights    ecologically    toxic    mutation    crop    capitalizing    phenotypic    heavy    collection    environmental    uniquely    ranges    composition    homeostasis    evolve    arise    critical    edaphic    data    network    variants    gene    comparatively    manner    unusually    taxa    implicated    mediators    mosaic    undergone    architecture    evolution    compositions   

Project "LEAP-EXTREME" data sheet

The following table provides information about the project.

Coordinator
RUHR-UNIVERSITAET BOCHUM 

Organization address
address: UNIVERSITAETSSTRASSE 150
city: BOCHUM
postcode: 44801
website: www.rub.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 2˙498˙675 €
 EC max contribution 2˙498˙675 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-ADG
 Funding Scheme ERC-ADG
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2023-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    RUHR-UNIVERSITAET BOCHUM DE (BOCHUM) coordinator 2˙498˙675.00

Map

 Project objective

The discontinuous mosaic of soil compositions on the Earth’s changeable surface intermittently requires the adaptation of plants as crucial mediators for ecosystems with the inorganic lithosphere harbouring all nutrient, but also toxic minerals. Only few gene variants have been implicated in local soil adaptation. There is a general lack of information about their relation with soil composition in the field, the manner in which such adaptations function and evolve, and why they arise in some taxa but never in others. To answer these questions, we will take advantage of the repeated evolution and the unusually large phenotypic ranges for multiple edaphic traits in Arabidopsis halleri. This species has undergone uniquely divergent natural selection for increased hyperaccumulation in leaves of the toxic metals zinc and cadmium as well as metal hypertolerance on ordinary soils, and for enhanced hypertolerance involving attenuated metal hyperaccumulation on heavy metal-contaminated soils. Capitalizing on the most comprehensive collection ever established of a wild extremophile, and with a pioneering approach recording critical field data for each genotype, we will conduct large-scale genome resequencing and identify multi-trait multi-gene associations, complemented by genetic linkage mapping based on crosses. Local edaphic adaptation causal variants will be placed into the context of metal homeostasis network architecture and plasticity using transcriptomics, and we will comparatively evaluate mutation rates in A. halleri under ecologically relevant edaphic conditions. Implementing state-of-the-art genome-enabled and novel phenotyping methodologies in this wild and biologically complex species will require continuous pioneering developments. Our work will deliver novel fundamental insights into local adaptation in plants and identify large-effect gene variants with potential for applications in environmental restoration, biotechnology and crop breeding.

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