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BactoBubble SIGNED

Microscale investigation of key bacterial phenotypes enhancing collection by rising bubbles and aerial dispersal

Total Cost €

0

EC-Contrib. €

0

Partnership

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 BactoBubble project word cloud

Explore the words cloud of the BactoBubble project. It provides you a very rough idea of what is the project "BactoBubble" about.

largely    multidisciplinary    cells    atmospheric    interfaces    linking    fundamental    certain    microscopy    drive    h2    aerial    burst    nutrient    encounter    motility    surface    aerosolisation    interaction    interactions    microscopic    ecology    microscale    enrichment    characterization    group    aerosols    underlies    disease    model    optical    collection    dispersal    containing    particles    varying    microbes    levels    societal    enhanced    bacterial    builds    innovative    changing    little    internationally    hypotheses    bubbles    originates    springboard    complemented    independent    impacts    experiments    starkly    domain    channel    apart    training    pinned    cell    thereby    career    phenomena    microfluidics    eject    bacteria    starvation    vary    quantify    combining    spreading    rising    predictive    microfluidic    first    alter    size    mathematical    mutants    bubble    h1    starving    microbial    scientific    observation    environmental    marine    microdroplets    modeling    recognised    modify    poor    species    flow    ocean    global    rates    inert    transport   

Project "BactoBubble" data sheet

The following table provides information about the project.

Coordinator
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH 

Organization address
address: Raemistrasse 101
city: ZUERICH
postcode: 8092
website: https://www.ethz.ch/de.html

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 175˙419 €
 EC max contribution 175˙419 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-06-01   to  2020-11-17

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH CH (ZUERICH) coordinator 175˙419.00

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 Project objective

Aerial transport of microbes has fundamental consequences for microbial dispersal, disease spreading, and atmospheric phenomena. In the ocean, aerosolisation largely originates from collection of bacteria by rising bubbles, which burst at the surface and eject cells in microdroplets. This process underlies the enrichment of bacteria in aerosols. While we know that collection rates vary among bacterial species, we know little about the bacterial properties promoting collection, and even less about which factors drive enhanced collection of certain species. Combining state-of-the-art microfluidics and microscopy, I will provide the first microscopic observation of bubble-bacteria interaction, to investigate two hypotheses: H1: Cell motility increases microbial collection by rising bubbles. Motility sets bacteria starkly apart from inert particles, likely promoting collection by increasing encounter rates and changing surface properties. H2: Starvation increases microbial collection by rising bubbles. Starving bacteria modify their surface and size, which may enhance collection by bubbles, thereby promoting dispersal from nutrient poor areas. To investigate H1 and H2, I will develop a novel microfluidic flow channel containing a pinned bubble, and use advanced optical microscopy to quantify collection rates for a range of bacteria. Experiments using mutants to alter motility (H1) and varying starvation levels (H2) will be complemented by characterization of bacterial surface properties. I will also develop the first mathematical model predictive for microbial aerosolisation. This project builds on my experience in modeling and interfaces, enhanced by training in microfluidics and marine microbial ecology within an internationally recognised multidisciplinary group, in order to open an innovative domain linking microscale interactions with global-scale scientific, environmental and societal impacts, and provide a springboard towards an independent research career.

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