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BactoBubble SIGNED

Microscale investigation of key bacterial phenotypes enhancing collection by rising bubbles and aerial dispersal

Total Cost €

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EC-Contrib. €

0

Partnership

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 BactoBubble project word cloud

Explore the words cloud of the BactoBubble project. It provides you a very rough idea of what is the project "BactoBubble" about.

builds    largely    interaction    particles    environmental    varying    springboard    rates    h2    containing    disease    motility    microfluidic    experiments    innovative    spreading    bubble    model    alter    aerosols    pinned    optical    modeling    linking    inert    complemented    modify    starkly    thereby    microscopic    size    burst    global    certain    microfluidics    ocean    aerosolisation    microdroplets    aerial    mathematical    bacteria    fundamental    starving    apart    societal    originates    collection    microscopy    recognised    bubbles    scientific    impacts    cell    training    microbes    predictive    changing    first    domain    encounter    independent    microscale    surface    quantify    ecology    bacterial    rising    internationally    starvation    h1    career    phenomena    channel    poor    little    species    multidisciplinary    dispersal    levels    nutrient    combining    interactions    transport    cells    vary    enhanced    group    microbial    flow    drive    characterization    hypotheses    enrichment    interfaces    mutants    atmospheric    marine    eject    underlies    observation   

Project "BactoBubble" data sheet

The following table provides information about the project.

Coordinator
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH 

Organization address
address: Raemistrasse 101
city: ZUERICH
postcode: 8092
website: https://www.ethz.ch/de.html

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 175˙419 €
 EC max contribution 175˙419 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-06-01   to  2020-11-17

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH CH (ZUERICH) coordinator 175˙419.00

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 Project objective

Aerial transport of microbes has fundamental consequences for microbial dispersal, disease spreading, and atmospheric phenomena. In the ocean, aerosolisation largely originates from collection of bacteria by rising bubbles, which burst at the surface and eject cells in microdroplets. This process underlies the enrichment of bacteria in aerosols. While we know that collection rates vary among bacterial species, we know little about the bacterial properties promoting collection, and even less about which factors drive enhanced collection of certain species. Combining state-of-the-art microfluidics and microscopy, I will provide the first microscopic observation of bubble-bacteria interaction, to investigate two hypotheses: H1: Cell motility increases microbial collection by rising bubbles. Motility sets bacteria starkly apart from inert particles, likely promoting collection by increasing encounter rates and changing surface properties. H2: Starvation increases microbial collection by rising bubbles. Starving bacteria modify their surface and size, which may enhance collection by bubbles, thereby promoting dispersal from nutrient poor areas. To investigate H1 and H2, I will develop a novel microfluidic flow channel containing a pinned bubble, and use advanced optical microscopy to quantify collection rates for a range of bacteria. Experiments using mutants to alter motility (H1) and varying starvation levels (H2) will be complemented by characterization of bacterial surface properties. I will also develop the first mathematical model predictive for microbial aerosolisation. This project builds on my experience in modeling and interfaces, enhanced by training in microfluidics and marine microbial ecology within an internationally recognised multidisciplinary group, in order to open an innovative domain linking microscale interactions with global-scale scientific, environmental and societal impacts, and provide a springboard towards an independent research career.

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