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denovoSkin

Personalized, bio-engineered skin grafts for the permanent treatment of skin defects.

Total Cost €

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EC-Contrib. €

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Partnership

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 denovoSkin project word cloud

Explore the words cloud of the denovoSkin project. It provides you a very rough idea of what is the project "denovoSkin" about.

global    commercialisation    human    movement    market    leaves    skin    patients    14m    surgeries    issue    starting    50m    off    classified    avoids    graft    interventions    painful    site    performance    granted    sized    transplantation    clinical    scar    epidermal    financial    invested    meet    patient    shortage    fda    deployment    corrective    swissmedic    life    plan    sme    care    considerable    projected    follow    drug    fast    last    impair    burden    hence    reduce    structure    considerably    every    manufacture    bio    orphan    57m    engineered    intervention    quantities    world    restore    rehabilitation    homecare    scars    investment    chain    medical    defects    donor    debilitating    dermo    demand    permanent    savings    automation    quality    surgical    treatment    atmp    sound    significantly    standard    disfiguring    excision    economic    16    autografting    burns    denovoskin    function    biopsy    solid    health    outstanding    wounds    therapy    fits    intense    suffer    trade    psychosocial    designation    solving    instrument    patented    stamp    personalized    minimally    ema   

Project "denovoSkin" data sheet

The following table provides information about the project.

Coordinator
CUTISS AG 

Organization address
address: WEINBERGSTRASSE 35 WYSS TRANSLATIONAL CENTER ZURICH DENOVOS
city: ZURICH
postcode: 8006
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Project website http://cutiss.swiss/
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.2.1.5. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced manufacturing and processing)
2. H2020-EU.2.1.3. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials)
3. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
4. H2020-EU.2.1.2. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2018
 Duration (year-month-day) from 2018-01-01   to  2018-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CUTISS AG CH (ZURICH) coordinator 50˙000.00

Map

 Project objective

Every year in the world, more than 50M patients suffer from skin defects (e.g. burns, excision, etc.) and need surgical intervention to restore skin function. Standard of care, skin autografting, very often leaves these patients with scars. Scars are permanent and disfiguring, and can also be painful and highly debilitating. Indeed, they may also impair movement and growth, and require several follow-up surgeries, intense homecare and psychosocial rehabilitation. Hence, scars significantly affect patient’s quality of life, along with the economic burden for the health-care system. Furthermore, in the case of large wounds, donor site shortage represents a real clinical issue. denovoSkin™ is a patented, personalized, bio-engineered human skin graft classified as Advanced Therapy Medical Product (ATMP). It is engineered in large quantities starting-off from a stamp-sized skin biopsy of the patient, thus solving the donor site shortage issue. Moreover, because of its dermo-epidermal structure, denovoSkin is expected to minimally scar after transplantation. Its outstanding performance could considerably reduce or even avoids further corrective interventions, allowing for considerable savings in terms of costs. denovoSkin™ is granted with Orphan Drug Designation for the treatment of burns by Swissmedic, EMA and FDA. So far, more than €14M have been invested over the last 16 years of research into the development and the clinical testing of denovoSkin™. To have denovoSkin™ fully projected at a European and global level we need a further investment of €3.57M to set up a solid EU value chain able to meet the large demand expected during the commercialisation via developing the automation of manufacture. The proposed work in Phase 1 of the SME instrument fits into our overall plan to reach the market by contributing the financial resources needed to plan a fast sound wider deployment of denovoSkin™ and its market uptake.

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The information about "DENOVOSKIN" are provided by the European Opendata Portal: CORDIS opendata.

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