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denovoSkin SIGNED

Personalized, bio-engineered skin grafts for the permanent treatment of skin defects

Total Cost €

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EC-Contrib. €

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Partnership

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 denovoSkin project word cloud

Explore the words cloud of the denovoSkin project. It provides you a very rough idea of what is the project "denovoSkin" about.

investment    outstanding    logistics    atmp    de    5m    burns    human    shortage    stamp    biopsy    debilitating    transplantation    defects    therapy    swissmedic    sized    care    16    classified    leads    entire    dermo    minimal    risking    trade    corrective    orphan    autologous    permanent    psychosocial    designation    sme    wounds    rehabilitation    sound    quality    financial    bio    considerable    57m    intervention    engineered    patient    restore    deployment    impair    economic    scars    medical    performance    leaves    intense    solving    interventions    hence    disfiguring    off    painful    movement    life    projected    plan    follow    avoids    patients    fits    granted    suffer    fast    graft    instrument    worldwide    surgeries    world    standard    epidermal    reduce    donor    17    clinical    fda    personalized    invested    scarrring    starting    assuring    last    structure    skin    homecare    drug    automate    autografting    excision    site    market    every    considerably    quantities    denovoskin    issue    savings    significantly    patented    treatment    health    optimal    surgical    ema    burden    50m    function    global   

Project "denovoSkin" data sheet

The following table provides information about the project.

Coordinator
CUTISS AG 

Organization address
address: WEINBERGSTRASSE 35 WYSS TRANSLATIONAL CENTER ZURICH DENOVOS
city: ZURICH
postcode: 8006
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Project website https://cutiss.swiss/
 Total cost 3˙571˙237 €
 EC max contribution 2˙499˙866 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-2
 Funding Scheme SME-2
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2020-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CUTISS AG CH (ZURICH) coordinator 2˙499˙866.00

Map

 Project objective

Every year in the world, more than 50M patients suffer from skin defects (e.g. burns, excision, etc.) and need surgical intervention to restore skin function. Standard of care, skin autografting, very often leaves these patients with scars. Scars are permanent and disfiguring, and can also be painful and highly debilitating. Indeed, they may also impair movement and growth, and require several follow-up surgeries, intense homecare and psychosocial rehabilitation. Hence, scars significantly affect patient’s quality of life, along with the economic burden for the health-care system. Furthermore, in the case of large wounds, donor site shortage represents a real clinical issue.

denovoSkin™ is a patented, personalized, autologous bio-engineered human skin graft classified as Advanced Therapy Medical Product (ATMP). It is engineered in large quantities starting-off from a stamp-sized skin biopsy of the patient, thus solving the donor site shortage issue. Moreover, because of its dermo-epidermal structure, denovoSkin™ leads to minimal scarrring after transplantation. Its outstanding performance could considerably reduce or even avoids further corrective interventions, allowing for considerable savings in terms of costs. denovoSkin™ is also granted with Orphan Drug Designation for the treatment of burns by Swissmedic, EMA and FDA.

So far, more than €17.5M have been invested over the last 16 years of research into the development and the clinical testing of denovoSkin™. To have denovoSkin™ fully projected at a European and global level we need a further investment of €3.57M to automate its production, de-risking the entire denovoSkin™ project by assuring a real delivery to patients worldwide while providing optimal logistics and quality of product.

The proposed work in Phase 2 of the SME instrument fits into our overall plan to reach the market by contributing the financial resources needed to plan a fast sound wider deployment of denovoSkin™ and its market uptake.

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The information about "DENOVOSKIN" are provided by the European Opendata Portal: CORDIS opendata.

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