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aDDRess SIGNED

Joint Training and Research Program on Chromatin Dynamics and the DNA Damage Response

Total Cost €

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EC-Contrib. €

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Partnership

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 aDDRess project word cloud

Explore the words cloud of the aDDRess project. It provides you a very rough idea of what is the project "aDDRess" about.

activation    faithfully    genes    devastating    intellectual    rare    instability    sophisticated    genome    stronger    basic    defects    additional    esrs    play    transmitted    transcription    light    industry    damage    multidisciplinary    counteract    socioeconomic    age    functional    basis    vital    grounds    carefully    smes    nucleosome    excellence    prospects    translational    shed    careers    functionally    repair    architecture    health    reveals    diseases    abnormalities    causal    independent    paths    mechanisms    syndrome    roles    collaborations    metabolic    training    platform    ranging    create    series    action    successful    biological    individual    intact    chromatin    labs    reprogramming    human    relevance    scientific    employment    requiring    maintenance    participating    onto    threatening    direct    progeny    complications    transform    cells    cancer    discoveries    designed    durable    pushed    quality    biogenesis    cellular    links    onset    life    battery    remodeling    premature    integrating    developmental    dna    neurodegeneration    disease    trigger    rna    network   

Project "aDDRess" data sheet

The following table provides information about the project.

Coordinator
IDRYMA TECHNOLOGIAS KAI EREVNAS 

Organization address
address: N PLASTIRA STR 100
city: IRAKLEIO
postcode: 70013
website: www.forth.gr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Greece [EL]
 Total cost 4˙011˙939 €
 EC max contribution 4˙011˙939 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2018
 Funding Scheme MSCA-ITN-ETN
 Starting year 2019
 Duration (year-month-day) from 2019-03-01   to  2023-02-28

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    IDRYMA TECHNOLOGIAS KAI EREVNAS EL (IRAKLEIO) coordinator 486˙035.00
2    KOBENHAVNS UNIVERSITET DK (KOBENHAVN) participant 297˙522.00
3    NORGENOTECH AS NO (OSLO) participant 292˙342.00
4    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 281˙982.00
5    ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE CH (LAUSANNE) participant 281˙276.00
6    GENEVIA TECHNOLOGIES OY FI (TAMPERE) participant 280˙805.00
7    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) participant 274˙802.00
8    LXREPAIR FR (LA TRONCHE) participant 274˙802.00
9    UNIVERSITE DE PARIS FR (PARIS) participant 274˙802.00
10    STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS NL (AMSTERDAM) participant 265˙619.00
11    IFOM FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE IT (MILANO) participant 261˙499.00
12    KLINIKUM DER UNIVERSITAET ZU KOELN DE (KOELN) participant 252˙788.00
13    LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN DE (MUENCHEN) participant 252˙788.00
14    FAKULTNI NEMOCNICE U SV. ANNY V BRNE CZ (Brno) participant 234˙871.00
15    UNIVERSITE PARIS DIDEROT - PARIS 7 FR (PARIS) participant 0.00
16    ETAIRIA DIACHIRISIS KAI ANAPTIXIS EPISTIMONIKOU KAI TECHNOLOGIKOU PARKOU KRITIS AE EL (HERAKLION) partner 0.00
17    PANEPISTIMIO KRITIS EL (RETHIMNO) partner 0.00
18    SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE IT (TRIESTE) partner 0.00
19    UNIVERSITAET ZU KOELN DE (KOELN) partner 0.00
20    UNIVERSITE DE GENEVE CH (GENEVE) partner 0.00

Map

 Project objective

Defects in DNA repair trigger a number of devastating health complications ranging from developmental abnormalities to the premature onset of age-related diseases, including the metabolic syndrome, neurodegeneration and cancer. To counteract genome instability, cells have evolved a battery of DNA repair mechanisms ensuring that their genome remains functionally intact and is faithfully transmitted to progeny. Recent work reveals that DNA repair factors play additional roles in vital biological processes, including nucleosome remodeling, chromatin architecture, RNA biogenesis or the transcription activation of genes involved in cellular reprogramming and growth. These recent discoveries have pushed the DNA repair field forward and towards new grounds requiring a series of sophisticated functional and multidisciplinary approaches. Based on these novel scientific paths, we have carefully designed the “aDDRess” consortium on the basis of past excellence of the individual participants and their relevance to the proposed field. The action addresses a major research topic i.e. DNA damage in development and disease with great socioeconomic impact in Europe and direct relevance to human health. The objectives of the program are: i. to create a European research platform of excellence in the field of DNA repair by integrating research from basic mechanisms to translational research applications, ii. to establish a Network dedicated to the high-quality training of ESRs promoting their independent careers and future employment prospects, iii. to transform our current successful, long-term collaborations into a stronger intellectual network and build durable links between the participating labs and the industry (SMEs). Understanding the relevance of genome maintenance pathways to human health will shed light onto the causal mechanisms of rare and widespread life-threatening diseases, including cancer.

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