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MicroLightProtoCell SIGNED

Microfluidics-assisted design and construction of light-responsive protocells

Total Cost €


EC-Contrib. €






 MicroLightProtoCell project word cloud

Explore the words cloud of the MicroLightProtoCell project. It provides you a very rough idea of what is the project "MicroLightProtoCell" about.

architectures    precisely    add    micromachines    harnessed    construct    assembly    protocellular    inherent    replication    alternative    precise    date    laurence    extremely    light    functions    last    benefit    manipulated    activated    prof    edge    jean    life    rudimentary    groups    baret    structurally    locally    photo    sensing    interactions    societal    christophe    responsive    inertia    ph    minimal    unattainable    energy    space    microfluidics    navailles    expertise    primitive    forms    remarkable    remote    tackle    smart    cutting    skills    attractive    precedent    chemicals    reliability    manipulation    origin    powerful    actuation    biology    cellularity    compartmentalization    exhibiting    constitute    provides    actuated    time    dr    few    cnrs    made    literature    environmental    cells    models    materials    multidisciplinary    hosting    spatiotemporal    clean    class    protocell    leadership    progress    guidance    resolution    activation    drug    types    silenced    conventional    performed    modularity    understand    synthetic    protocells    fine    exploited    sensitivity   

Project "MicroLightProtoCell" data sheet

The following table provides information about the project.


Organization address
address: RUE MICHEL ANGE 3
city: PARIS
postcode: 75794

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 173˙076 €
 EC max contribution 173˙076 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2020-09-30


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

Protocells are synthetic models of cells exhibiting rudimentary life-like properties, such as compartmentalization, sensing or replication, and constitute as such primitive forms of cellularity that could help to understand the origin of life. The remarkable properties of these smart micromachines can also be harnessed to tackle key societal challenges, including environmental clean-up, energy production, or drug delivery. Advances in this field would greatly benefit from the precise activation of protocells in both space and time. However, fine control over protocellular functions has been minimal to date. Conventional types of actuation (e.g. T, pH) do not allow spatiotemporal guidance due to their inherent inertia or the need to add chemicals. Light provides an attractive alternative for the remote manipulation of protocells with an extremely high spatiotemporal resolution. However, there is no precedent of light-actuated protocells in the literature. The aim of this proposal is precisely to design and construct a new class of photo-responsive protocells capable of being manipulated, activated or silenced quickly and locally in response to light. The bottom-up protocell assembly will be performed by microfluidics, whose powerful abilities in terms of modularity, reliability or sensitivity will be exploited to produce structurally well-defined architectures, and study interactions between protocells in a way unattainable with traditional methods. The expertise and skills of the applicant in the field of protocell design and light-responsive materials will be applied to the multidisciplinary and cutting-edge fields of microfluidics and synthetic biology in which the hosting groups at CNRS (under the leadership of Prof. Jean-Christophe Baret and Dr. Laurence Navailles) have made significant progress in the last few years.

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The information about "MICROLIGHTPROTOCELL" are provided by the European Opendata Portal: CORDIS opendata.

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