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MicroLightProtoCell SIGNED

Microfluidics-assisted design and construction of light-responsive protocells

Total Cost €

0

EC-Contrib. €

0

Partnership

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 MicroLightProtoCell project word cloud

Explore the words cloud of the MicroLightProtoCell project. It provides you a very rough idea of what is the project "MicroLightProtoCell" about.

remarkable    exploited    conventional    activation    energy    micromachines    class    life    light    laurence    resolution    precedent    locally    spatiotemporal    multidisciplinary    responsive    space    made    actuated    drug    minimal    cellularity    precise    chemicals    expertise    benefit    assembly    replication    reliability    dr    models    compartmentalization    smart    groups    societal    inertia    modularity    hosting    prof    add    synthetic    forms    cutting    construct    manipulated    navailles    origin    functions    environmental    protocell    microfluidics    rudimentary    activated    biology    date    harnessed    photo    literature    clean    sensing    precisely    structurally    types    powerful    edge    cells    performed    constitute    jean    ph    primitive    skills    extremely    protocells    few    leadership    materials    sensitivity    last    remote    interactions    tackle    exhibiting    alternative    christophe    progress    cnrs    guidance    attractive    inherent    protocellular    fine    manipulation    understand    silenced    baret    provides    unattainable    architectures    actuation    time   

Project "MicroLightProtoCell" data sheet

The following table provides information about the project.

Coordinator		 CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS 

Organization address
address: RUE MICHEL ANGE 3
city: PARIS
postcode: 75794
website: www.cnrs.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country France [FR]
 Total cost 173˙076 €
 EC max contribution 173˙076 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2020-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) coordinator 173˙076.00

Map

 Project objective

Protocells are synthetic models of cells exhibiting rudimentary life-like properties, such as compartmentalization, sensing or replication, and constitute as such primitive forms of cellularity that could help to understand the origin of life. The remarkable properties of these smart micromachines can also be harnessed to tackle key societal challenges, including environmental clean-up, energy production, or drug delivery. Advances in this field would greatly benefit from the precise activation of protocells in both space and time. However, fine control over protocellular functions has been minimal to date. Conventional types of actuation (e.g. T, pH) do not allow spatiotemporal guidance due to their inherent inertia or the need to add chemicals. Light provides an attractive alternative for the remote manipulation of protocells with an extremely high spatiotemporal resolution. However, there is no precedent of light-actuated protocells in the literature. The aim of this proposal is precisely to design and construct a new class of photo-responsive protocells capable of being manipulated, activated or silenced quickly and locally in response to light. The bottom-up protocell assembly will be performed by microfluidics, whose powerful abilities in terms of modularity, reliability or sensitivity will be exploited to produce structurally well-defined architectures, and study interactions between protocells in a way unattainable with traditional methods. The expertise and skills of the applicant in the field of protocell design and light-responsive materials will be applied to the multidisciplinary and cutting-edge fields of microfluidics and synthetic biology in which the hosting groups at CNRS (under the leadership of Prof. Jean-Christophe Baret and Dr. Laurence Navailles) have made significant progress in the last few years.

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The information about "MICROLIGHTPROTOCELL" are provided by the European Opendata Portal: CORDIS opendata.

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