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Pre-natal exposure to urban AIR pollution and pre- and post-Natal Brain development

Total Cost €


EC-Contrib. €






 AIR-NB project word cloud

Explore the words cloud of the AIR-NB project. It provides you a very rough idea of what is the project "AIR-NB" about.

hazard    forming    interventions    samplers    impulse    least    pollution    regional    dose    pollutants    independently    mediated    nanoparticles    mediation    detecting    measuring    establishing    citizens    myelination    paternal    post    sensors    gestation    particulate    replication    genuinely    external    structure    foetal    neonates    personal    permanent    cognitive    injury    impairs    inhaled    prenatal    dysfunction    contrasting    school    context    structures    windows    900    brain    health    neo    motor    cohort    effect    airborne    pregnant    stress    period    levels    women    age    anatomical    appears    postnatal    pregnancy    time    placenta    stressors    function    profound    underlying    environmental    vulnerable    utero    postulate    create    data    vascular    urban    lack    mathematical    policy    translocation    causality    exposure    total    stages    air    imaging    connectivity    inadequate    natal    noise    mainly    placental    protect   

Project "AIR-NB" data sheet

The following table provides information about the project.


Organization address
address: C ROSSELLO 132 PLANTA 05
postcode: 8036

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 2˙499˙992 €
 EC max contribution 2˙499˙992 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-ADG
 Funding Scheme ERC-ADG
 Starting year 2018
 Duration (year-month-day) from 2018-09-01   to  2023-08-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

Air pollution is the main urban-related environmental hazard. It appears to affect brain development, although current evidence is inadequate given the lack of studies during the most vulnerable stages of brain development and the lack of brain anatomical structure and regional connectivity data underlying these effects. Of particular interest is the prenatal period, when brain structures are forming and growing, and when the effect of in utero exposure to environmental factors may cause permanent brain injury. I and others have conducted studies focused on effects during school age which could be less profound. I postulate that: pre-natal exposure to urban air pollution during pregnancy impairs foetal and postnatal brain development, mainly by affecting myelination; these effects are at least partially mediated by translocation of airborne particulate matter to the placenta and by placental dysfunction; and prenatal exposure to air pollution impairs post-natal brain development independently of urban context and post-natal exposure to air pollution. I aim to evaluate the effect of pre-natal exposure to urban air pollution on pre- and post-natal brain structure and function by following 900 pregnant women and their neonates with contrasting levels of pre-natal exposure to air pollutants by: i) establishing a new pregnancy cohort and evaluating brain imaging (pre-natal and neo-natal brain structure, connectivity and function), and post-natal motor and cognitive development; ii) measuring total personal exposure and inhaled dose of air pollutants during specific time-windows of gestation, noise, paternal stress and other stressors, using personal samplers and sensors; iii) detecting nanoparticles in placenta and its vascular function; iv) modelling mathematical causality and mediation, including a replication study in an external cohort. The expected results will create an impulse to implement policy interventions that genuinely protect the health of urban citizens.

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The information about "AIR-NB" are provided by the European Opendata Portal: CORDIS opendata.

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lastchecktime (2020-07-10 15:23:19) correctly updated