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MetaboliQs SIGNED

Leveraging room temperature diamond quantum dynamics to enable safe, first-of-its-kind, multimodal cardiac imaging

Total Cost €

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EC-Contrib. €

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Partnership

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MetaboliQs project word cloud

Explore the words cloud of the MetaboliQs project. It provides you a very rough idea of what is the project "MetaboliQs" about.

hyperpolarized excellence personalize difficult confidently therapeutics positron innovative therapy synthetic pet breakthrough appropriate quantum first metabolic diagnostics mri treatment diseases imaging nv people previously globally fabrication cvds grade diamonds tum tissue molecular brings outcomes die centers world companies unmet bruker eth resonance magnetic clinical tomography class nitrogen hyperpolarization polarization inventor death cardiovascular disease iaf multidisciplinary sensing circumstances newly realizing preclinical translate nvision fraunhofer unaddressed personalized expert leader market trials metaboliqs dynamics zurich chemical precision annually despite electron expertise medical unachievable quantification tools paramagnetic conduct accurately worldwide select institutes commercializing diamond vacancy diagnose emission patients cvd sensitive huji paving characterization care continental

Project "MetaboliQs" data sheet

The following table provides information about the project.

Coordinator	FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. Organization address address: HANSASTRASSE 27C city: MUNCHEN postcode: 80686 website: www.fraunhofer.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Germany [DE]
Total cost	6˙667˙801 €
EC max contribution	6˙667˙801 € (100%)
Programme	1. H2020-EU.1.2.3. (FET Flagships)
Code Call	H2020-FETFLAG-2018-03
Funding Scheme	RIA
Starting year	2018
Duration (year-month-day)	from 2018-10-01 to 2021-09-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. Organization address address: HANSASTRASSE 27C city: MUNCHEN postcode: 80686 website: www.fraunhofer.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (MUNCHEN)	coordinator	1˙500˙172.00
2	NVISION IMAGING TECHNOLOGIES GMBH NVISION IMAGING TECHNOLOGIES GMBH Organization address address: ALBERT-EINSTEIN-ALLEE city: ULM postcode: 89081 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (ULM)	participant	1˙430˙937.00
3	KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN Organization address address: ISMANINGER STRASSE 22 city: MUENCHEN postcode: 81675 website: http://www.med.tu.muenchen.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (MUENCHEN)	participant	1˙220˙401.00
4	ELEMENT SIX (UK) LIMITED ELEMENT SIX (UK) LIMITED Organization address address: GLOBAL INNOVATION CENTRE FERMI AVENUE city: HARWELL OXFORDSHIRE DIDCOT postcode: OX11 0QR website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (HARWELL OXFORDSHIRE DIDCOT)	participant	960˙290.00
5	EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH Organization address address: Raemistrasse 101 city: ZUERICH postcode: 8092 website: https://www.ethz.ch/de.html contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (ZUERICH)	participant	936˙812.00
6	THE HEBREW UNIVERSITY OF JERUSALEM THE HEBREW UNIVERSITY OF JERUSALEM Organization address address: EDMOND J SAFRA CAMPUS GIVAT RAM city: JERUSALEM postcode: 91904 website: www.huji.ac.il contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IL (JERUSALEM)	participant	390˙387.00
7	BRUKER BIOSPIN GMBH BRUKER BIOSPIN GMBH Organization address address: Am Silberstreifen city: RHEINSTETTEN postcode: 76287 website: www.bruker-biospin.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (RHEINSTETTEN)	participant	228˙800.00

Map

Project objective

Cardiovascular Diseases (CVDs) are the number 1 cause of death globally: more people die annually from CVDs than from any other cause. Despite emerging diagnostics tools and therapeutics, several areas of significant unmet need remain unaddressed among CVD patients. The ability to personalize cardiovascular medical care and improve outcomes, will require characterization of disease processes at a molecular level. The current state-of-the-art, e.g., Positron emission tomography (PET), does not provide detailed information about the chemical state of the tissue at a molecular level, therefore it remains difficult to accurately diagnose and confidently select appropriate therapy in many circumstances. The MetaboliQs project brings together two areas of European excellence - diamond-based quantum sensing and medical imaging. We will translate a newly developed hyperpolarization method for magnetic resonance imaging (MRI) based on the quantum dynamics of nitrogen-vacancy (NV) centers. This breakthrough quantum technology will enable previously unachievable, highly sensitive quantification of metabolic activity, paving the way for precision diagnostics and better personalized treatment of cardiovascular and other metabolic diseases. For realizing and eventually commercializing the technology, MetaboliQs brings together a world-class multidisciplinary consortium with end to end expertise - leading diamond quantum technology research institutes (Fraunhofer IAF - quantum-grade diamond growth and fabrication, HUJI - quantum sensing) and innovative companies (Element 6 - worldwide leader in synthetic diamonds, NVision - inventor of diamond-based polarization), as well as two expert users of hyperpolarized and cardiovascular MRI (TUM, ETH Zurich - first in continental Europe to conduct clinical trials of hyperpolarized MRI for cardiovascular disease) and the market leader in electron paramagnetic resonance and preclinical MRI (Bruker).

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