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CARE SIGNED

COMMON ACTION AGAINST HIV/TB/HCV ACROSS THE REGIONS OF EUROPE

Total Cost €

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EC-Contrib. €

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Partnership

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 CARE project word cloud

Explore the words cloud of the CARE project. It provides you a very rough idea of what is the project "CARE" about.

scientists    contracting    recommendations    pulmonary    susceptibility    networks    explore    regions    strategies    stakeholders    aids    events    russian    drugs    extrapulmonary    resistant    plans    correlations    permitting    genomic    expertise    expansion    daa    clinical    validate    tool    epidemiology    introduction    extensive    longer    researchoutputs    reactions    communication    intervention    realization    antiretroviral    hcv    first    treatment    phenotype    cohorts    subtopics    therapy    tb    training    care    line    highest    genotype    instis    representative    infrastructure    frame    mdr    cohort    derive    distinguished    russia    region    decision    hiv    coinfection    variants    longitudinal    recognised    created    prioritisation    drug    host    mechanisms    discover    genetic    serious    collections    soluble    subtypes    share    adverse    protocols    competence    containment    timeframe    influencing    data    fight    epidemics    relationship    brings    biomarkers    distribute    structured   

Project "CARE" data sheet

The following table provides information about the project.

Coordinator
EURESIST NETWORK GEIE 

Organization address
address: VIA GUIDO GUINIZELLI 98/100
city: ROMA RM
postcode: 152
website: www.euresist.org

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website https://www.careresearch.eu
 Total cost 3˙266˙842 €
 EC max contribution 2˙961˙912 € (91%)
 Programme 1. H2020-EU.3.1.1. (Understanding health, wellbeing and disease)
 Code Call H2020-SC1-2018-Single-Stage-RTD
 Funding Scheme RIA
 Starting year 2019
 Duration (year-month-day) from 2019-01-01   to  2020-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EURESIST NETWORK GEIE IT (ROMA RM) coordinator 378˙500.00
2    REGION HOVEDSTADEN DK (HILLEROD) participant 666˙875.00
3    UNIVERSITA DEGLI STUDI DI SIENA IT (SIENA) participant 402˙712.00
4    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 329˙950.00
5    IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE UK (LONDON) participant 298˙750.00
6    FORSCHUNGSZENTRUM BORSTEL DE (BORSTEL) participant 252˙500.00
7    EBERHARD KARLS UNIVERSITAET TUEBINGEN DE (TUEBINGEN) participant 156˙250.00
8    STATE INSTITUTION PUBLIC HEALTH CENTER OF THE MINISTRY OF HEALTH OF UKRAINE UA (KYIV) participant 130˙000.00
9    INFECTIOUS DISEASES, AIDS AND CLINICAL IMMUNOLOGY RESEARCH CENTER GE (TIBLISI) participant 128˙250.00
10    "INSTITUTIA MEDICO-SANITARA PUBLICA - INSTITUTUL DE FTIZIOPNEUMOLOGIE ""CHIRIL DRAGANIUC""" MD (CHISINAU) participant 128˙125.00
11    VIESOJI ISTAIGA VILNIAUS UNIVERSITETO LIGONINE SANTAROS KLINIKOS LT (VILNIUS) participant 90˙000.00
12    FEDERAL RESEARCH CENTRE FOR EPIDEMIOLOGY AND MICROBIOLOGY NAMED AFTERTHE HONORARY ACADEMICIAN N.F. GAMALEYA OF THE MINISTRY OF HEALTH RU (MOSCOW) participant 0.00

Map

 Project objective

CARE brings together distinguished scientists and highly representative networks in the European region, including Russia, in the fight against HIV/TB/HCV. CARE research objectives are based on already established European cohort networks with extensive and longitudinal data and/or sample collections. Together with new data and sample collections and cohorts created during the project, CARE will produce high-level researchoutputs during the two years of the project timeframe. The specific short term objectives are to: ● Discover and validate novel soluble biomarkers of MDR-TB treatment success and of pulmonary TB. ● Explore host genetic mechanisms of susceptibility to extrapulmonary TB. ● Analyse genotype to phenotype correlations in MDR-TB and develop a decision making support tool. ● Define epidemiology and pathways of drug-resistant HIV, including their relationship with HIV subtypes and TB coinfection to support an evidence-based introduction of INSTIs as part of first line antiretroviral therapy. ● Discover and validate host genomic variants influencing susceptibility to contracting AIDS and serious non-AIDS clinical events and adverse reactions to drugs. ● Derive best practice recommendations for DAA prioritisation strategies for HCV treatment. The longer-term objective of CARE is to implement a research infrastructure that allows the expansion of activities beyond the funding frame, permitting the partners to share technology, protocols, structured data collections and knowledge. Finally, CARE activities include realization of recommendations and intervention plans, communication to the stakeholders, dissemination and training activities in order to develop and distribute the highest expertise and competence throughout the European region for the containment of the epidemics.CARE is fully in line with the call topic and addresses all its subtopics. It involves a recognised Russian partner coordinating 5 top level institutions covering the regions of Russia.

 Publications

year authors and title journal last update
List of publications.
2020 K. B. Gromov, E. V. Kazennova, D. E. Kireev, A. V. Murzakova, A. E. Lopatukhin, M. R. Bobkova
Analysis of HIV-1 (Human immunodeficiency virus-1, Lentivirus, Orthoretrovirinae, Retroviridae) Nef protein polymorphism of variants circulating in the former USSR countries
published pages: 281-290, ISSN: 0507-4088, DOI: 10.36233/0507-4088-2019-64-6-281-290
Problems of Virology, Russian journal 64/6 2020-02-18
2020 V. Yu. Laga, A. V. Nemykin, E. N. Begma, A. M. Strakhova, N. A. Vasilyeva, E. N. Ozhmegova, A. A. Antonova, M. R. Bobkova
MOLECULAR GENETIC ANALYSIS OF HIV-1 VARIANTS CIRCULATING IN THE REPUBLIC OF CRIMEA
published pages: 91-97, ISSN: 2077-9828, DOI: 10.22328/2077-9828-2019-11-4-91-97
HIV Infection and Immunosuppressive Disorders 11/4 2020-02-13
2019 Dmitry Neshumaev, Aleksey Lebedev, Marina Malysheva, Anatoly Boyko, Sergey Skudarnov, Ekaterina Ozhmegova, Anastasia Antonova, Elena Kazennova, Marina Bobkova
Molecular Surveillance of HIV-1 Infection in Krasnoyarsk Region, Russia: Epidemiology, Phylodynamics and Phylogeography
published pages: 114-125, ISSN: 1570-162X, DOI: 10.2174/1570162x17666190618155816
Current HIV Research 17/2 2019-12-16
2019 Francesco Saladini, Alessia Giannini, Adele Boccuto, Filippo Dragoni, Alice Appendino, Edoardo Albanesi, Ilaria Vicenti, Maurizio Zazzi
Comparable in vitro activity of second-generation HIV-1 integrase strand transfer inhibitors (INSTIs) on HIV-1 clinical isolates with INSTI resistance mutations
published pages: , ISSN: 0066-4804, DOI: 10.1128/aac.01717-19
Antimicrobial Agents and Chemotherapy 2019-12-16
2019 Shambhu G. Aralaguppe, Anoop T. Ambikan, Manickam Ashokkumar, Milner M. Kumar, Luke Elizabeth Hanna, Wondwossen Amogne, Anders Sönnerborg, Ujjwal Neogi
MiDRMpol: A High-Throughput Multiplexed Amplicon Sequencing Workflow to Quantify HIV-1 Drug Resistance Mutations against Protease, Reverse Transcriptase, and Integrase Inhibitors
published pages: 806, ISSN: 1999-4915, DOI: 10.3390/v11090806
Viruses 11/9 2019-12-16

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