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STOICISM SIGNED

Stochastic Communication Inside Cortical Microcolumns

Total Cost €

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EC-Contrib. €

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Partnership

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 STOICISM project word cloud

Explore the words cloud of the STOICISM project. It provides you a very rough idea of what is the project "STOICISM" about.

invasive    understand    hyttinen    interdisciplinary    methodology    discovery    15    dynamics    200    neuroscience    academic    neuronal    move    million    silico    theories    center    propagation    failures    molecular       29    cortical    communication    society    stoicism    billion    scales    death    explained    produces    collaborate    newly    training    theory    variation    2mm    drug    detection    experiments    dollars    prof    neuron    potentially    quantify    disease    biomeditech    neurological    alzheimer    stochastic    model    supervised    researcher    microcolumn    strategies    light    action    astrocyte    65    historically    ageing    people    communications    perform    formed    plasticity    pathologies    appropriate    neurodegeneration    world    complete    microcolumns    computational    area    biophysics    rate    he    jari    scenario    longer    vitro    biological    caused    annum    experimentation    behaviours    renowned    neurology    inside    signal    synaptic    modelled    analyze   

Project "STOICISM" data sheet

The following table provides information about the project.

Coordinator
TAMPEREEN KORKEAKOULUSAATIO SR 

Organization address
address: KALEVANTIE 4
city: TAMPERE
postcode: 33100
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Finland [FI]
 Total cost 202˙680 €
 EC max contribution 202˙680 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2019
 Duration (year-month-day) from 2019-09-02   to  2021-09-01

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TAMPEREEN KORKEAKOULUSAATIO SR FI (TAMPERE) coordinator 202˙680.00

Map

 Project objective

Neurodegeneration, such as Alzheimer’s disease, currently affects 15 million people in the US with a death rate of 29.5% among 65 years old and produces a cost around 200 billion dollars per annum. These type of pathologies are caused by neuronal communication failures in multi-scales of the cortical microcolumns. Neuroscience has historically provided theories and experiments to explain the signal propagation and neurodegeneration inside cortical microcolumns, but these behaviours are far from being fully explained. The newly formed research area of molecular communications can bring light to this challenge by using information and communication theory in this scenario. A novel interdisciplinary methodology (multi-scale modelling neurological modelling information theory) can analyze and quantify the dynamics in the synaptic plasticity and provide further understanding about cortical microcolumns. With this approach, STOICISM project aims to i) model the multi-scale cortical microcolumn neurology; ii) model and quantify the neuronal communication; iii) investigate the long-term plasticity dynamics and control strategies. STOICISM will develop a complete in-silico model of the 2mm cortical microcolumn that will account for its multi-scale communication. The synaptic plasticity variation will be modelled as a stochastic model based on in-vitro experimentation of the neuron-astrocyte communication. This action requires the researcher to move to a world-center in computational biophysics, such as BioMediTech, where he can get appropriate training, perform biological experiments and collaborate with other top researchers while being supervised by the renowned leading academic Prof. Jari Hyttinen. STOICISM will change the way we understand the effects of neurodegeneration which will enable future non-invasive detection and drug discovery, potentially creating a longer-term impact on the ageing society.

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The information about "STOICISM" are provided by the European Opendata Portal: CORDIS opendata.

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