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STOICISM SIGNED

Stochastic Communication Inside Cortical Microcolumns

Total Cost €

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EC-Contrib. €

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Partnership

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 STOICISM project word cloud

Explore the words cloud of the STOICISM project. It provides you a very rough idea of what is the project "STOICISM" about.

annum    propagation    disease    experiments    neuronal    quantify    produces    neurodegeneration    15    failures    formed    synaptic    caused    signal    researcher       billion    200    computational    cortical    hyttinen    biological    rate    prof    people    communication    he    historically    strategies    drug    dynamics    communications    microcolumns    academic    alzheimer    dollars    explained    renowned    pathologies    discovery    potentially    area    plasticity    modelled    longer    newly    experimentation    65    theories    collaborate    ageing    world    molecular    society    death    jari    theory    stochastic    scales    neuron    model    training    behaviours    light    move    analyze    center    perform    supervised    2mm    microcolumn    interdisciplinary    million    appropriate    inside    29    scenario    biomeditech    vitro    methodology    variation    neuroscience    understand    action    neurology    neurological    biophysics    complete    invasive    detection    stoicism    astrocyte    silico   

Project "STOICISM" data sheet

The following table provides information about the project.

Coordinator
TAMPEREEN KORKEAKOULUSAATIO SR 

Organization address
address: KALEVANTIE 4
city: TAMPERE
postcode: 33100
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Finland [FI]
 Total cost 202˙680 €
 EC max contribution 202˙680 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2019
 Duration (year-month-day) from 2019-09-02   to  2021-09-01

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TAMPEREEN KORKEAKOULUSAATIO SR FI (TAMPERE) coordinator 202˙680.00

Map

 Project objective

Neurodegeneration, such as Alzheimer’s disease, currently affects 15 million people in the US with a death rate of 29.5% among 65 years old and produces a cost around 200 billion dollars per annum. These type of pathologies are caused by neuronal communication failures in multi-scales of the cortical microcolumns. Neuroscience has historically provided theories and experiments to explain the signal propagation and neurodegeneration inside cortical microcolumns, but these behaviours are far from being fully explained. The newly formed research area of molecular communications can bring light to this challenge by using information and communication theory in this scenario. A novel interdisciplinary methodology (multi-scale modelling neurological modelling information theory) can analyze and quantify the dynamics in the synaptic plasticity and provide further understanding about cortical microcolumns. With this approach, STOICISM project aims to i) model the multi-scale cortical microcolumn neurology; ii) model and quantify the neuronal communication; iii) investigate the long-term plasticity dynamics and control strategies. STOICISM will develop a complete in-silico model of the 2mm cortical microcolumn that will account for its multi-scale communication. The synaptic plasticity variation will be modelled as a stochastic model based on in-vitro experimentation of the neuron-astrocyte communication. This action requires the researcher to move to a world-center in computational biophysics, such as BioMediTech, where he can get appropriate training, perform biological experiments and collaborate with other top researchers while being supervised by the renowned leading academic Prof. Jari Hyttinen. STOICISM will change the way we understand the effects of neurodegeneration which will enable future non-invasive detection and drug discovery, potentially creating a longer-term impact on the ageing society.

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The information about "STOICISM" are provided by the European Opendata Portal: CORDIS opendata.

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