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STOICISM SIGNED

Stochastic Communication Inside Cortical Microcolumns

Total Cost €

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EC-Contrib. €

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Partnership

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 STOICISM project word cloud

Explore the words cloud of the STOICISM project. It provides you a very rough idea of what is the project "STOICISM" about.

he    area    action    neurological       behaviours    communication    potentially    experimentation    center    perform    million    dynamics    caused    jari    neuronal    signal    training    methodology    2mm    longer    hyttinen    discovery    biomeditech    scales    people    world    researcher    produces    neurology    analyze    academic    neuron    communications    invasive    theory    explained    disease    ageing    move    model    renowned    dollars    neurodegeneration    alzheimer    rate    modelled    65    complete    microcolumns    inside    scenario    cortical    stoicism    synaptic    annum    supervised    formed    appropriate    variation    prof    failures    historically    light    stochastic    15    interdisciplinary    propagation    death    pathologies    theories    200    quantify    drug    astrocyte    silico    billion    biophysics    plasticity    experiments    microcolumn    understand    vitro    collaborate    strategies    detection    biological    newly    society    29    neuroscience    molecular    computational   

Project "STOICISM" data sheet

The following table provides information about the project.

Coordinator
TAMPEREEN KORKEAKOULUSAATIO SR 

Organization address
address: KALEVANTIE 4
city: TAMPERE
postcode: 33100
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Finland [FI]
 Total cost 202˙680 €
 EC max contribution 202˙680 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2019
 Duration (year-month-day) from 2019-09-02   to  2021-09-01

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TAMPEREEN KORKEAKOULUSAATIO SR FI (TAMPERE) coordinator 202˙680.00

Map

 Project objective

Neurodegeneration, such as Alzheimer’s disease, currently affects 15 million people in the US with a death rate of 29.5% among 65 years old and produces a cost around 200 billion dollars per annum. These type of pathologies are caused by neuronal communication failures in multi-scales of the cortical microcolumns. Neuroscience has historically provided theories and experiments to explain the signal propagation and neurodegeneration inside cortical microcolumns, but these behaviours are far from being fully explained. The newly formed research area of molecular communications can bring light to this challenge by using information and communication theory in this scenario. A novel interdisciplinary methodology (multi-scale modelling neurological modelling information theory) can analyze and quantify the dynamics in the synaptic plasticity and provide further understanding about cortical microcolumns. With this approach, STOICISM project aims to i) model the multi-scale cortical microcolumn neurology; ii) model and quantify the neuronal communication; iii) investigate the long-term plasticity dynamics and control strategies. STOICISM will develop a complete in-silico model of the 2mm cortical microcolumn that will account for its multi-scale communication. The synaptic plasticity variation will be modelled as a stochastic model based on in-vitro experimentation of the neuron-astrocyte communication. This action requires the researcher to move to a world-center in computational biophysics, such as BioMediTech, where he can get appropriate training, perform biological experiments and collaborate with other top researchers while being supervised by the renowned leading academic Prof. Jari Hyttinen. STOICISM will change the way we understand the effects of neurodegeneration which will enable future non-invasive detection and drug discovery, potentially creating a longer-term impact on the ageing society.

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The information about "STOICISM" are provided by the European Opendata Portal: CORDIS opendata.

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