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ConscBreathDynamics SIGNED

Breathing dynamics in health and disease: how consciousness shape respiratory patterns

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 ConscBreathDynamics project word cloud

Explore the words cloud of the ConscBreathDynamics project. It provides you a very rough idea of what is the project "ConscBreathDynamics" about.

dynamics    model    clinical    hour    sectional    record    neural    functional    unresponsive    tools    perhaps    healthy    basic    utilizing    continues    occurring    regulation    trigger    imaging    vision    elucidate    influence    fold    differentiating    unconsciously    electrophysiology    first    recording    computational    shape    relationship    rare    magnetic    significance    diagnostic    paradigm    minimally    individuals    physiological    function    respiratory    potentially    underlying    simplicity    interplay    cross    vegetative    consciousness    uws    last    olfaction    interaction    intend    mechanisms    tool    recovery    consciously    breathing    mcs    combination    intricate    designed    conscious    multimodal    mainly    indicate    patients    electroencephalogram    vital    vigilance    fmri    awareness    24    tracking    neuroimaging    classifier    deceptive    questions    resonance    automated    plan    detect    opportunity    human    syndrome    mechanism    doc    disorders    longitudinal    neuroscience    fundamental    audition    respiration    despite    eeg    wakefulness    vs    employing    prognostic   

Project "ConscBreathDynamics" data sheet

The following table provides information about the project.

Coordinator
INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE 

Organization address
address: BOULEVARD DE L'HOPITAL 47
city: PARIS
postcode: 75013
website: http://icm-institute.org/

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 196˙707 €
 EC max contribution 196˙707 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-03-01   to  2022-02-28

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE FR (PARIS) coordinator 196˙707.00

Map

 Project objective

Breathing is perhaps the most vital physiological function, and it is occurring mainly unconsciously. Yet, despite the deceptive simplicity of breathing, it is an intricate behaviour influence by conscious top-down control and vigilance state. How consciousness shape breathing? What are the neural mechanisms underlying conscious control of breathing? Can breathing dynamics indicate on conscious awareness? We aim to address these questions by employing basic and clinical neuroscience approaches in combination with electrophysiology, neuroimaging and advanced computational tools. Disorders of consciousness (DOC) including vegetative state (VS)/unresponsive wakefulness syndrome (UWS) and minimally conscious state (MCS) offer a unique model to investigate the relationship between consciousness and breathing, by providing a rare opportunity for cross-sectional and longitudinal tracking of breathing dynamics during recovery of consciousness. In the proposed research, we first aim to characterize the interaction between breathing and consciousness state. To do this we will record continues respiration during 24-hour from healthy individuals and DOC patients. Next, we intend to elucidate the neural mechanism underlying conscious regulation of breathing, by recording electroencephalogram (EEG) and functional resonance magnetic imaging (fMRI) activity during a multimodal (olfaction, audition and vision) paradigm designed to consciously and unconsciously trigger respiratory change. Last, we plan to investigate whether breathing dynamics can be used as a diagnostic and potentially prognostic tool to detect awareness in DOC patients, by developing an automated respiratory-based classifier differentiating between UWS and MCS patients. The significance of this study is two-fold; addressing fundamental questions in breathing regulation, and utilizing the interplay between basic physiological function and consciousness to better human condition.

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The information about "CONSCBREATHDYNAMICS" are provided by the European Opendata Portal: CORDIS opendata.

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